About Sickkids
About SickKids

Christopher Caldarone, MD, FRCSC

The Hospital for Sick Children
Surgeon-in-Chief
Department of Surgery

Staff Cardiovascular Surgeon
Cardiovascular Surgery

Chief
Perioperative Services

Research Institute
Senior Associate Scientist
Physiology & Experimental Medicine

University of Toronto
Professor, Department of Surgery
Chair, Division of Cardiac Surgery


Phone: 416-813-7794
Fax: 416-813-7369
e-mail: christopher.caldarone@sickkids.ca
Alternate Contact: Clinic contact
Alternate Phone: 416-813-6420
Alternate Fax: 416-813-7984

Research Interests

Pulmonary Vein Stenosis

Pulmonary Vein Stenosis is a major unsolved problem in congenital heart disease. When limited to the junction of the pulmonary veins in the left atrium, surgical therapy is often successful. Unfortunately, pulmonary vein vasculopathy often extends upstream into the lung parenchyma with a very high mortality rate. We are examining pelagic mechanisms of upstream pulmonary vein stenosis using cell-based, mouse and porcine models.

Cardiovascular Data Management Centre

The Cardiovascular Data Management Centre (CVDMC) collects clinical data from patients with cardiovascular disease across the entire University of Toronto. The data is aggregated in a linkage-rich environment which fosters quality improvement initiatives and clinical research.

Achievements

  • 2016 – Robert B. Salter Chair of Surgical Research
  • 2015 – Surgeon-in-Chief, Department of Surgery
  • 2013 – Associate Editor, Journal of Thoracic and Cardiovascular Surgery
  • 2009 – Chair, Division of Cardiac Surgery, University of Toronto
  • 2007 – Editorial Board, Journal of Thoracic and Cardiovascular Surgery

Publications

Recent Publications (2011 - present)

Rahkonen O, Chaturvedi RR, Benson L, Honjo O, Caldarone CA, Lee KJ. Pulmonary artery stenosis in hybrid single-ventricle palliation: High incidence of left pulmonary artery intervention. J Thorac Cardiovasc Surg. 2014 Dec 3. pii: S0022-5223. Coauthor or Collaborator.

Zhu J, Ide H, Fu YY, Teichert AM, Kato H, Weisel RD, Maynes JT, Coles JG, Caldarone CA. Losartan ameliorates “upstream” pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis. J Thorac Cardiovasc Surg. 2014 Dec 1;148(6):2550-7. Senior Responsible Author.

Kotani Y, Chetan D, Saedi A, Zhu J, Grosse-Wortmann L, Coles JG, Caldarone CA, Van Arsdell GS, Honjo O. Persistent fenestration may be a marker for physiologic intolerance after Fontan completion. J Thorac Cardiovasc Surg. 2014 Dec 1;148(6):2532-8. Coauthor or Collaborator.

Poynter JA, Bondarenko I, Austin EH, DeCampli WM, Jacobs JP, Ziemer G, Kirshbom PM, Tchervenkov CI, Karamlou T, Blackstone EH, Walters HL 3rd, Gaynor JW, Mery CM, Pearl JM, Brothers JA, Caldarone CA, Williams WG, Jacobs ML, Mavroudis C, Congenital Heart Surgeons’ Society AAOCA Working Group. Repair of anomalous aortic origin of a coronary artery in 113 patients: a Congenital Heart Surgeons’ Society report. World J Pediatr Congenit Heart Surg. 2014 Oct 1;5(4):507-14. Coauthor or Collaborator.

Kotani Y, Anggriawan S, Chetan D, Zhao L, Liyanage N, Saedi A, Mertens LL, Caldarone CA, Van Arsdell GS, Honjo O. Fate of the hypoplastic proximal aortic arch in infants undergoing repair for coarctation of the aorta through a left thoracotomy. Ann Thorac Surg. 2014 Oct 1;98(4):1386-93. Coauthor or Collaborator.

Caldarone LA, Caldarone CA, Vricella LA. Retroesophageal total anomalous pulmonary venous connection in a neonate. J Thorac Cardiovasc Surg. 2014 Aug 1;148(2):e143-5. Principal Author.

McCrindle BW, Clarizia NA, Khaikin S, Holtby HM, Manlhiot C, Schwartz SM, Caldarone CA, Coles JG, Van Arsdell GS, Scherer SW, Redington AN. Remote ischemic preconditioning in children undergoing cardiac surgery with cardiopulmonary bypass: a single-center double-blinded randomized trial. J Am Heart Assoc. 2014 Jul 28;3(4):pii: e000964. Coauthor or Collaborator.

Kato H, Fu YY, Zhu J, Wang L, Aafaqi S, Rahkonen O, Slorach C, Traister A, Leung CH, Chiasson D, Mertens L, Benson L, Weisel RD, Hinz B, Maynes JT, Coles JG, Caldarone CA. Pulmonary vein stenosis and the pathophysiology of “upstream” pulmonary veins. J Thorac Cardiovasc Surg. 2014 Jul 1;148(1):245-53. Senior Responsible Author.

Wald RM, Altaha MA, Alvarez N, Caldarone CA, Cavallé-Garrido T, Dallaire F, Drolet C, Grewal J, Hancock Friesen CL, Human DG, Hickey E, Kayedpour C, Khairy P, Kovacs AH, Lebovic G, McCrindle BW, Nadeem SN, Patton DJ, Redington AN, Silversides CK, Tham EB, Therrien J, Warren AE, Wintersperger BJ, Vonder Muhll IF, Farkouh ME. Rationale and Design of the Canadian Outcomes Registry Late After Tetralogy of Fallot Repair: The CORRELATE Study. Can J Cardiol. 2014 Jun 24. Coauthor or Collaborator.

Nathan M, Sleeper LA, Ohye RG, Frommelt PC, Caldarone CA, Tweddell JS, Lu M, Pearson GD, Gaynor JW, Pizarro C, Williams IA, Colan SD, Dunbar-Masterson C, Gruber PJ, Hill K, Hirsch-Romano J, Jacobs JP, Kaltman JR, Kumar SR, Morales D, Bradley SM, Kanter K, Newburger JW, Pediatric Heart Network Investigators. Technical performance score is associated with outcomes after the Norwood procedure. J Thorac Cardiovasc Surg. 2014 Jun 19. Coauthor or Collaborator.

Sarrazy V, Koehler A, Chow ML, Zimina E, Li CX, Kato H, Caldarone CA, Hinz B. Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction. Cardiovasc Res. 2014 Jun 1;102(3):407-17. Coauthor or Collaborator.

Vanderlaan RD, Caldarone CA, Backx PH. Heart failure in congenital heart disease: the role of genes and hemodynamics. Pflugers Arch. 2014 Jun 1;466(6):1025-35. Co-Principal Author.

Zhu J, Kotani Y, Chetan D, Zhao L, Coles JG, Caldarone CA, Van Arsdell GS, Honjo O. Is restrictive atrial septal defect a risk in partial anomalous pulmonary venous drainage repair? Ann Thorac Surg. 2014 May 1;97(5):1664-70. Epub 2014 Mar 20. Coauthor or Collaborator.

Jacobs JP, Pasquali SK, Austin E, Gaynor JW, Backer C, Hirsch-Romano JC, Williams WG, Caldarone CA, McCrindle BW, Graham KE, Dokholyan RS, Shook GJ, Poteat J, Baxi MV, Karamlou T, Blackstone EH, Mavroudis C, Mayer JE Jr, Jonas RA, Jacobs ML. Linking the congenital heart surgery databases of the Society of Thoracic Surgeons and the Congenital Heart Surgeons’ Society: part 1--rationale and methodology. World J Pediatr Congenit Heart Surg. 2014 Apr 1;5(2):256-71. Coauthor or Collaborator.

Jacobs JP, Pasquali SK, Austin E, Gaynor JW, Backer C, Hirsch-Romano JC, Williams WG, Caldarone CA, McCrindle BW, Graham KE, Dokholyan RS, Shook GJ, Poteat J, Baxi MV, Karamlou T, Blackstone EH, Mavroudis C, Mayer JE Jr, Jonas RA, Jacobs ML. Linking the congenital heart surgery databases of the Society of Thoracic Surgeons and the Congenital Heart Surgeons’ Society: part 2--lessons learned and implications. World J Pediatr Congenit Heart Surg. 2014 Apr 1;5(2):272-82. Coauthor or Collaborator.

Leung CH, Wang L, Nielsen JM, Tropak MB, FU YY, Kato H, Callahan J, Regington AN, Caldarone CA. Remote Cardioprotection by Transfer of Coronary Effluent from Ischemic Preconditioned Rabbit Heart Preserves Mitochondrial Integrity and Function via Adenosine Receptor Activation. Cardiovascular Drugs Therapy. 2014 Feb;28(1):7-17. Co-Principal Author.

Babu B, Caldarone CA. Management of tetralogy of fallot with unilateral absence of pulmonary artery: an overview. World Journal Pediatric Congenital Heart Surgery. 2014 Jan 1;5(1):70-9. Coauthor or Collaborator.

Honjo O, Kotani Y, Bharucha T, Mertens L, Caldarone CA, Redington AN, Van Arsdell G. Anatomical factors determining surgical decision-making in patients with transposition of the great arteries with left ventrical outflow tract obstruction. European Journal Cardiothoracic Surgery. 2013 Dec;44(6):1085-94. discussion 1094. Coauthor or Collaborator.

Poynter JA, Eghtesady P, McCrindle BW, Walters HL 3rd, Krishorn PM, Blackstone EH, Husain SA, Overman DM, Austin EH, Karamlou T, Lodge AJ, St Louis JD, Gruber PJ, Ziemer G, Davies RR, Jacobs JP, Brown JW, Williams WG, Tchervenkov CI, Jacobs ML, Caldarone CA; Congenital Heart Surgeons Society. Association of pulmonary conduit type and size wit durability in infants and young children. Annals Thoracic Surgery. 2013 Nov;96(5):1695-701. discussion 1701-2. Senior Responsible Author.

Kotani Y, Chetan D, Zhu J, Anand V, Calderon CA, Van Arsdell GS, Coles JG, Honjo O. The natural and surgically modified history of anomalous pulmonary veins from the left lung. Annals Thoracic Surgery. 2013 Nov;96(5):1711-8. discussion 1718-20. Coauthor or Collaborator.

Kato H, Fu YY, Zhu J, Wang L, Aafaqi S, Rahkonen O, Slorach C, Traister A, Leung CH, Chiasson D, Mertens L, Benson L, Weisel RD, Hinz B, Maynes JT, Coles GG, Caldarone CA. Pulmonary vein stenosis and the pathophysiology of “upstream” pulminary veins. J Thorac Cardiovasc Surg. 2013 Sep 28. pii: S0022-5223(13)00966-5. [Epub ahead of print]. In Press. Senior Responsible Author.

Chetan D, Kotani Y, Jacques F, Poynter JA, Benson LN, Lee KJ, Chaturvedi RR, Friedberg MK, Van Arsdell GS, Caldarone CA, Honjo O. Surgical palliation strategy does not afect interstage venticular dysfunction or atrioventricular valve regurgitation in children with hypoplastic left heart syndrom and variants. Circulation. 2013 Sep 10;128(11 Suppl 1):S205-12. Coauthor or Collaborator.

Kotani Y, Tweddell J, Gruber P, Pizzaro C, Austin EH 3rd, Woods RK, Gruenwald C, Caldarone CA. Current cardioplegia practice in pediatric surgery: a North American multiinstitutional survey. Annals Thoracic Surgery. 2013 Sep;96(3):923-9. Senior Responsible Author.

Baba K, Honjo O, Chaturvedi RR, Lee KJ, Van Arsdell G, Caldarone CA, Benson LN. “Reverse Blalock-Taussig shunt”: Application in single ventricle hybrid palliation. J Thorac Cardiovasc Surg. 2013 Aug;146(2):352-7. Epub 2012 Dec 8. Coauthor or Collaborator.

Kotani Y, Chetan K, Ono N, Mertens LL, Caldarone CA, Van Arsdell GS, Honjo O. Late functional outcomes after repair of tetralogy of Fallot with atrioventricular septal defect: A double case-match control study. J Thorac Cardiovasc Surg. 2013 Jun;145(6):1477-84, 1484.e1-4. Epub 2013 Feb 16. Coauthor or Collaborator.

Jacques F, Anand V, Hickey EJ, Kotani Y, Yadava M, Alghamdi A, Caldarone CA, Redington AN, Schwartz S, Van Arsdell GS. Medical errors: The performance gap in hypoplastic left heart syndrome and physiologic equivalents? J Thorac Cardiovasc Surg. 2013 Jun;145(6):1465-73. discussion 1473-5. Epub 2013 Feb 20. Coauthor or Collaborator.

Cohen MS, Jegatheeswaran A, Baffa JM, Gremmels DB, Overman DM, Caldarone CA, McCrindle BW, Mertens L. Echocardiographic features defining right dominant unbalanced atrioventricular septal defect: A multi-institutional study of the Congenital Heart Surgeon’s Soceity. Circulation: Cardiovascular Imaging. 2013 Jun;6(4):508-13. In: Pediatric Cardiac Surgery (Mavroudis, C., Backer, C. eds). Coauthor or Collaborator.

Koziol J, Gertler R, Manlhiot C, McCrindle B, Holtby H, Caldarone CA, Taylor K. The effect of intraoperative hypotension on the outcomes of initial hybrid palliation for single ventricle congenital heart disease: a historical cohort study. Can J Anaesth. 2013 May;60(5):465-70. Epub 2013 Feb 26. Coauthor or Collaborator.

Baba K, Chaturvedi R, Lee KJ, Caldarone CA, Benson LN. Fate of the ductal stent after hybrid palliation for hypoplastic left heart syndrome. The Annals of Thoracic Surgery. 2013 May;95(5):1660-4. Coauthor or Collaborator.

Algarni KD, Weisel RD, Caldarone CA, Maganti M, Tsang K, Yau TM. Microplegia during coronary artery bypass grafting was associated with less low cardiac output syndrome: a propensity-matched comparison. The Annals of Thoracic Surgery. 2013 May;95(5):1532-8. Coauthor or Collaborator.

Karamlou T, Poynter JA, Walters HL 3rd., Rhodes J, Bondarenko I, Pasquail SK, Fuller SM, Lambert LM, Blackstone EH, Jacobs ML, Duncan L, Caldarone CA, Williams WG, McCrindle BW. Long-term functional health status and excercise test variables for patients with pulmonary artesia with intact ventricular septum: a Congenital Heart Surgeons Society study. J Thorac Cardiovasc Surg. 2013 Apr;145(4):1018-25. discussion 1025-7. Coauthor or Collaborator.

Bharucha T, Honjo O, Atlin C, Redington A, Caldarone CA, Van Arsdell GS, Mertens L. Mechanisms of Tricuspid Valve Regurgitation in Hypoplastic Left Heart Syndrome: A Case-Matched Echocardiographic-Surgical Comparison Study. Eur Heart J Cardiovasc Imaging. 2013 Feb;14(2):135-41. Epub 2012 Jun 20. Coauthor or Collaborator.

Kotani Y, Chetan D, Atlin CR, Mertens LL, Jegatheeswaran A, Caldarone CA, Van Arsdell GS, Honjo O. Longevity and durability of atrioventricular valve repair in single ventricle patients. The Annals of Thoracic Surgery. 2012 Dec;94(6):2061-9. Coauthor or Collaborator.

Ceballos A, Argueta-Morales IR, Divo E, Osorio R, Caldarone CA, Kassab AJ, Decampli WM. Computational analysis of hybrid Norwood circulation with distal aortic arch obstruction and reverse Blalock-Taussig shunt. Ann Thorac Surg. 2012 Nov;94(5):1540-50. Coauthor or Collaborator.

Kotani Y, Honjo O, Shani K, Merklinger SL, Caldarone C, Van Arsdell G. Is Indexed Preoperative Superior Vena Cava Blood Flow a Risk Factor in Patients Undergoing Bidirectional Cavopulmonary Shunt. The Annals of Thoracic Surgery. 2012 Nov;94(5):1578-83. Epub 2012 Jul 12. Coauthor or Collaborator.

Tobler D, Crean Am, Redington AN, Van Arsdell GS, Caldarone CA, Nanthakumar K, Stambach D, Dos L, Wintersperger BJ, Oechslin EN, Silversides CK, Wald RM. The left heart after pulmonary valve replacement in adults late after tetralogy of Fallot repair. Int J Cardiol. 2012 Oct 18;160(3):165-70. Epub 2011 May 12. Coauthor or Collaborator.

Tabbutt S, Ghanayem N, Ravishankar C, Sleeper LA, Cooper DS, Frank DU, Lu M, Pizarro C, Frommelt P, Goldberg CS, Graham EM, Krawczeski CD, Lai WW, Lewis A, Kirsh JA, Mahony L, Ohye RG, Simsic J, Lodge AJ, Spurrier E, Stylianou M, Laussen P; Pediatric Heart Network Investigators. Risk factors for hospital morbidity and mortality after the Norwood procedure: A report from the Pediatric Heart Network Single Ventricle Reconstruction trial. Journal of Thoracic and Cardiovascular Surgery. 2012 Oct;144(4):882-95. Coauthor or Collaborator.

Ghanayem NS, Allen KR, Tabbutt S, Atz AM, Clabby ML, Cooper DS, Eghtesady P, Frommelt PC, Gruber PJ, Hill KD, Kaltman JR, Laussen PC, Lewis AB, Lurito KJ, Minich LL, Ohye RG, Schonbeck JV, Schwartz SM, Singh RK, Goldberg CS; Pediatric Heart Network Investigators. Interstage mortality after the Norwood procedure: Results of the multicenter Single Ventricle Reconstruction trial. The Journal of Thoracic and Cardiovascular Surgery. 2012 Oct;144(4):896-906. Coauthor or Collaborator.

Ohye RG, Schonbeck JV, Eghtesady P, Laussen PC, Pizarro C, Shrader P, Frank DU, Graham EM, Hill KD, Jacobs JP, Kanter KR, Kirsh JA, Lambert LM, Lewis AB, Ravishankar C, Tweddell JS, Williams IA, Pearson GD; Pediatric Heart Network Investigators. Cause, timing, and location of death in the Single Ventricle Reconstruction trial. Journal of Thoracic and Cardiovascular Surgery. 2012 Oct;144(4):907-14. Coauthor or Collaborator.

Baba K, Kotani Y, Chetan D, Chaturvedi RR, Lee KJ, Benson LN, Grosse-Wortmann L, Van Arsdell GS, Caldarone CA, Honjo O. Hybrid versus Norwood strategies for single-ventricle palliation. Circulation. 2012 Sep 11;126(11 Suppl 1):S123-31. Coauthor or Collaborator.

Manlhiot C, Brandao LR, Kwok J, Kegel S, Menjak IB, Carew CL, Chan AK, Schwartz SM, Sivarajan VB, Caldarone CA, Van Arsdell GS, McCrindle BW. Thrombotic Complications and Thromboprophylaxis Across All Three Stages of Single Ventricle Heart Palliation. J Pediatr. 2012 Sep;161(3):513-519.e3. Epub 2012 Apr 17. Coauthor or Collaborator.

Hickey EJ, Caldarone CA, Blackstone EH, Williams WG, Yeh T Jr, Pizarro C, Lofland G, Tchervenkow CI, Pigula F, McCrindle BW. Biventricular strategies for neonatal critical aortic stenosis: High mortality associated with early reintervention. J Thorac Cardiovasc Surg. 2012 Aug;144(2):409-17, 417.e1. Epub 2012 Feb 11. Coauthor or Collaborator.

Jacques F, Kotani Y, Deva DP, Moller T, Oechslin E, Horlick E, Osten M, Crean A, Benson LN, Wintersperger BJ, Caldarone CA. Left Main Coronary Artery Compression Long Term After Repair of Conotruncal Lesions: The Bow String Conduit. The Annals of Thoracic Surgery. 2012 Jul. 2012 Jul;94(1):283-5. Senior Responsible Author.

Tweddell JS, Sleeper LA, Ohye RG, Williams IA, Mahony L, Pizarro C, Pemberton VL, Frommelt PC, Bradley SM, Cnota JF, Hirsch J, Kirshbom PM, Li JS, Pike N, Puchalski M, Ravishankar C, Jacobs JP, Laussen PC, McCrindle BW; Pediatric Heart Network Investigators. Intermediate-term mortality and cardiac transplantation in infants with single-ventricle lesions: risk factors and their interaction with shunt type. Journal of Thoracic and Cardiovascular Surgery. 2012 Jul;144(1):152-9. Coauthor or Collaborator.

Pasquali SK, Ohye RG, Lu M, Kaltman J, Caldarone CA, Pizarro C, Dunbar-Masterson C, Gaynor JW, Jacobs JP, Kaza AK, Newburger J, Rhodes JF, Scheurer M, Silver E, Sleeper LA, Tabbutt S, Tweddell J, Uzark K, Wells W, Mahle WT, Pearson GD. Variation in Perioperative Care Across Centers for Infants Undergoing the Norwood Procedure. The Journal of Thoracic and Cardiovascular Surgery. 2012 Jun 12. 2012 Jun 12. Coauthor or Collaborator.

Newburger JW, sleeper LA, Bellinger DC, Goldberg CS, Tabbutt S, Lu M, Mussatto KA, Williams IA, Gustafson KE, Mital S, Pike N, Sood E, Mahle WT, Cooper DS, Dunbar-Masterson C, Krawczeski CD, Lewis A, Menon SC, Pemberton VL, Ravishankar C, Atz TW, Ohye RG, Gaynor JW; Pediatric Heart Network Investigators. Early developmental outcome in children with hypoplastic left heart syndrome and related anomalies: the single ventricle reconstruction trial. Circulation. 2012 May 1;125(17):2081-81. Epub 2012 Mar 28. Coauthor or Collaborator.

Manlhiot C, McCrindle BW, Menjak IB, Yoon H, Holtby HM, Brandao LR, Chan AK, Schwartz SM, Sivarajan VB, Crawford-Lean L, Foreman C, Caldarone CA, Van Arsdell GS. Longer Blood Storage is Associated With Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery. Ann Thorac Surg. 2012 May;93(5):1563-9. Epub 2011 Dec 2. Coauthor or Collaborator.

Gruenwald CE, Manlhiot C, Abadilla AA, Kwork J, Maxwell S, Holtby HM, Brandao LR, Chan AK, Crawford-Lean L, Foreman C, Caldarone CA, Van Arsdell GS, McCrindle BW. Heparin Brand Is Associated With Postsurgical Outcomes in Children Undergoing Cardiac Surgery. The Annals of Thoracic Surgery. 2012 Mar;93(3):878-82. Coauthor or Collaborator.

Hickey EJ, McCrindle BW, Larsen SH, Benson L, Manlhiot C, Caldarone CA, Van Arsdell GS, McGrindle BM, Williams WG. Hypertrophic Cardiomyopathy in Childhood: Disease Natural History, Impact of Obstruction, and Its Influence on Survival. The Annals of Thoracic Surgery. 2012 Mar;93(3):840-8. Coauthor or Collaborator.

Dragulescu A, Golding F, Van Arsdell G, Caldarone C, Mertens L, Al-Radi O, Lee KJ. The Impact of Additional Epicardial Imaging to Transesophageal Echocardiography on Intraoperative Detection of Residual Lesions in Congenital Heart Surgery. J Thorac Cardiovasc Surg. 2012 Feb;143(2):361-7. Epub 2011 Jul 12. Coauthor or Collaborator.

Feinstein JA, Benson DW, Dubin AM, Cohen MS, Maxey DM, Mahle WT, Pahl E, Villafane J, Bhatt AB, Peng LF, Johnson BA, Marsden AL, Daniels CJ, Rudd NA, Caldarone CA, Mussatto KA, Morales DL, Ivy DD, Gaynor JW, Tweddell JS, Deal BJ, Furck AK, Rosenthal GL, Ohye RG, Ghanayem NS, Cheatham JP, Tworetzky W, Martin GR. Hypoplastic left heart syndrome: current considerations and expectations. Journal of the American College of Cardiology. 2012 Jan 3;59(1 Suppl):S1-42. Review. Coauthor or Collaborator.

Hickey EJ, Caldarone CA, McCrindle BW. Left ventricular hypoplasia: a spectrum of disease involving the left ventricular outflow tract, aortic valve, and aorta. Journal of the American College of Cardiology. 2012 Jan 3;59(1 Suppl):S43-54. Review. Coauthor or Collaborator.

Hickey EJ, Nosikova Y, Zhang H, Caldarone CA, Benson L, Redington A, Van Arsdell GS. Very Low-Birth-Weight Infants with Congenital Cardiac Lesions: Is There Merit in Delaying Intervention to Permit Growth and Maturation? Journal of Thoracic and Cardiovascular Surgery. 2012 Jan;143(1):126-136.e1. Coauthor or Collaborator.

Walsh MA, Merat M, La Rotta G, Joshi P, Joshi V, Tran T, Jarvis S, Caldarone CA, Van Arsdell GS, Redington AN, McCridle BW. Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Circulation. 2011 Dec;39(12):2599-604. Coauthor or Collaborator.

Elmi M, Hickey EJ, Williams WG, Van Arsdell G, Caldarone CA, McCrindle BW. Long-term tricuspid valve function after Norwood operation. J Thorac Cardiovasc Surg. 2011 Dec;142(6):1341-7.e4. Epub 2011 Jun 24. Coauthor or Collaborator.

Greenway SC, Yoo SJ, Baliulis G, Caldarone C, Coles J, Grosse-Wortmann L. Assessment of Pulmonary Veins After Atrio-Pericardial Anastomosis by Cardiovascular Magnetic Resonance. J Cardiovasc Magn Reson. 2011 Nov 21;13(1):72. Coauthor or Collaborator.

Manlhiot C, Menjak IB, Brandao LR, Gruenwald CE, Schwartz SM, Sivarajan VB, Yoon H, Maratta R, Carew CL, McMullen JA, Clarizia NA, Holtby HM, Williams S, Caldarone CA, Van Arsdell GS, Chan AK, McCrindle BW. Risk, Clinical Features, and Outcomes of Thrombosis Associated with Pediatric Cardiac Surgery. Circulation. 2011 Oct 4;124(14):1511-9. Coauthor or Collaborator.

Alghamdi AA, Yanagawa B, Singh SK, Horton A, Al-Radi OO, Caldarone CA. Balancing stenosis and regurgitation during mitral valve surgery in pediatric patients. Annals of Thoracic Surgery. 2011 Aug;92(2):680-4. Principal Author.

Honjo O, Atlin CR, Mertens L, Al-Radi OO, Redington AN, Caldarone CA, Van Arsdell GS. Atrioventricular valve repair in patients with functional single-ventricle physiology: Impact of ventricular and valve function and morphology on survival and reintervention. J Thorac Cardiovasc Surg. 2011 Aug;142(2):326-35. Coauthor or Collaborator.

Yanagawa B, Alghamdi AA, Dragulescu A, Viola N, Al-Radi OO, Mertens LL, Coles JG, Caldarone CA, Van Arsdell GS. Primary sutureless repair for “simple” total anomalous pulmonary venous connections: midterm results in a single institution. Journal of Thoracic and Cardiovascular Surgery. 2011 Jun;141(6):1346-54. Coauthor or Collaborator.

Atz AM, Hawkins JA, Lu M, Cohen MS, Colan SD, Jaggers J, Lacro RV, McCrindle BW, Margossian R, Mosca RS, Sleeper LA, Caldarone CA Minich LL, Pediatric Heart Network Investigators. Surgical management of complete atrioventricular septal defect: associations with surgical technique, age and trisomy 21. J Thorac Cardiovasc Surg. 2011 Jun;141(6):1371-9. Coauthor or Collaborator.

Clariza NA, Manlhiot C, Schwartz SM, Sivarajan VB, Maratta R, Holby HM, Gruenwald CE, Caldarone CA, Van Arsdell GS, McCrindle BW. Improved outcomes associated with intraoperative steroid use in high-risk pediatric cardiac surgery. Annals of Thoracic Surgery. 2011 Apr;91(4):1222-7. Coauthor or Collaborator.

Leung CH, Wang L, Fu YY, Yuen W, Caldarone CA. Transient mitochondrial permeability transition pore opening after neonatal cardioplegic arrest. J Thorac Cardiovasc Surg. 2011 Apr;141(4):975-82. Epub 2010 Sep 29. Senior Responsible Author.

Viola N, Alghamdi AA, Perrin DG, Wilson GJ, Coles JG, Caldarone CA. Primary pulmonary vein stenosis: The impact of sutureless repair on survival. J Thorac Cardiovasc Surg. 2011 Jan;142(2):344-50. Principal Author.

Hickey E, Caldarone CA. Surgical Management of Post-repair Pulmonary Vein Stenosis. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2011;14(1):101-8. Review. Senior Responsible Author.