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About Sickkids
About SickKids

December 22, 2014

In the Fold: New Drug Target Discovered

A team of researchers led by Dr. Julie Forman-Kay, Senior Scientist at SickKids, discovered a mechanism cells use to control a disordered protein involved in cancer and autism.

The study, published in the journal Nature, shows that a process called phosphorylation — adding phosphates to the protein— can fold the disordered protein to make it non-functional, in contrast to previous expectations.

Read the full story here http://medicine.utoronto.ca/news/fold-new-drug-target-discovered