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Publications

Reference Interval Publications

Karbasy K, Lin DC, Stoianov A, Chan MK, Bevilacqua V, Chen Y, Adeli K. Pediatric reference value distributions and covariate-stratified reference intervals for 29 endocrine and special chemistry biomarkers on the Beckman Coulter Immunoassay Systems: a CALIPER study of healthy community children. Clin Chem Lab Med. 2016 Apr 1;54(4):643-57.

Kelly J, Raizman JE, Bevilacqua V, Chan MK, Chen Y, Quinn F, Shodin B, Armbruster D, Adeli K. Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents. Clinica Chimica Acta. 2015 Aug 24;450:196-202.

Adeli K, Raizman JE, Chen Y, Higgins V, Nieuwesteeg M, Abdelhaleem M, Wong SL, Blais D. Complex biological profile of hematologic markers across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clinical Chemistry 2015 Aug;61(8):1075-86.

Adeli K, Higgins V, Nieuwesteeg M, Raizman JE, Chen Y, Wong SL, Blais D. Complex reference values for endocrine and special chemistry biomarkers across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clinical Chemistry 2015 Aug;61(8):1063-74.

Adeli K, Higgins V, Nieuwesteeg M, Raizman JE, Chen Y, Wong SL, Blais D. Biochemical marker reference values across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the gasis of the Canadian Health Measures Survey. Clinical Chemistry 2015 Aug;61(8):1049-62.

Teodoro-Morrison T, Kyriakopoulou L, Chen YK, Raizman JE, Bevilacqua V, Chan MK, Wan B, Yazdanpanah M, Schulze A, Adeli K. Dynamic biological changes in metabolic disease biomarkers in childhood and adolescence: A CALIPER study of healthy community children. Clinical Biochemistry 2015 Sep;48(13-14):828-36.

Raizman JE, Quinn F, Armbruster DA, Adeli K. Pediatric reference intervals for calculated free testosterone, bioavailable testosterone and free androgen index in the CALIPER cohort. Clinical Chemistry and Laboratory Medicine 2015 Sep 1;53(10):e239-43.

Devgun MS, Chan MK, El-Nujumi AM, Abara R, Armbruster D, Adeli K. Clinical decision limits for interpretation of direct bilirubin--a CALIPER study of healthy multiethnic children and case report reviews. Clinical Biochemistry 2015 Jan;48(1-2):93-6.

Bevilacqua V, Chan MK, Chen Y, Armbruster D, Schodin B, Adeli K. Pediatric population reference value distributions for cancer biomarkers and covariate- stratified reference intervals in the CALIPER cohort. Clinical Chemistry 2014 Dec;60(12):1532-42.

Adeli K. Closing the gaps in pediatric reference intervals: the CALIPER project - an update. Clinical Biochemistry 2014;epub ahead of print.

Raizman JE, Cohen AH, Teodoro-Morrison T, Wan B, Khun-Chen M, Wilkenson C, Bevilaqua V, Adeli K. Pediatric reference value distributions for vitamins A and E in the CALIPER cohort and establishment of age-stratified reference intervals. Clinical Biochemistry 2014; epub ahead of print.

Bailey D, Bevilacqua V, Colantonio DA, Pasic MD, Perumal N, Chan MK, Adeli K. Pediatric within-day biological variation and quality specifications for 38 biochemical markers in the CALIPER cohort. Clinical Chemistry. 2014 Mar;60(3):518-29.

Shaw JL, Cohen A, Konforte D, Binesh-Marvasti T, Colantonio DA, Adeli K. Validity of establishing pediatric reference intervals based on hospital patient data: a comparison of the modified Hoffmann approach to CALIPER reference intervals obtained in healthy children. Clinical Biochemistry 2014 Feb;47(3):166-72.

Konforte D, Shea JL, Kyriakopoulou L, Colantonio D, Cohen AH, Shaw J, Bailey D, Chan MK, Armbruster D, Adeli K. Complex biological pattern of fertility hormones in children and adolescents: a study of healthy children from the CALIPER cohort and establishment of pediatric reference intervals. Clinical Chemistry 2013;epub ahead of print.

Bailey D, Colantonio D, Kyriakopoulou L, Cohen AH, Chan MK, Armbruster D, Adeli K. Marked biological variance in endocrine and biochemical markers in childhood: establishment of pediatric reference intervals using healthy community children from the Canadian Laboratory Initiative for Pediatric Reference Intervals Cohort. Clinical Chemistry 2013;epub ahead of print.

Pasic MD, Colantonio DA, Chan MK, Venner AA, Brinc D, Adeli K. Influence of fasting and sample collection time on 38 biochemical markers in healthy children: a CALIPER substudy. Clinical Biochemistry 2012 Oct;45(15):1125-30.

Colantonio DA, Kyriakopoulou L, Chan MK, Daly CH, Brinc D, Venner AA, Pasic MD, Armbruster D, Adeli K. Closing the gaps in pediatric laboratory reference intervals: a CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children. Clinical Biochemistry 2012 May;58(5):854-68.

Henderson MP, Grey V. Establishing and evaluating pediatric thyroid reference intervals on the Roche Modular Analytics e 170 using computational statistics and data-mining techniques. Clinical Biochemistry 2011;44:767-70.

Huang Y, Eapen E, Steele S, Grey V. Establishment of reference intervals for bone markers in children and adolescents. Clinical Biochemistry 2011;44:771-8.

Blasutig IM, Jung B, Kulasingam V, Baradaran S, Chen Y, Chan MK, Colantonio D, Adeli K. Analytical evaluation of the Vitros 5600 integrated system in a pediatric setting and determination of pediatric reference intervals. Clinical Biochemistry 2010;43:1039-44.

Kulasingam V, Jung BP, Blasutig IM, Baradaran S, Chan MK, Aytekin M, Colantonio D, Adeli K. Pediatric reference intervals for 28 chemistries and immunoassays on the Roche Cobas 6000 analyzer--a caliper pilot study. Clinical Biochemistry 2010;43:1045-50.

Chan MK, Seiden-Long I, Aytekin M, Quinn F, Ravalico T, Ambruster D, Adeli K. Canadian laboratory initiative on pediatric reference interval database (CALIPER): Pediatric reference intervals for an integrated clinical chemistry and immunoassay analyzer, Abbott Architect ci8200. Clinical Biochemistry 2009;42:885-91.

Yip PM, Chan MK, Nelken J, Lepage N, Brotea G, Adeli K. Pediatric reference intervals for lipids and apolipoproteins on the Vitros 5,1 FS chemistry system. Clinical Biochemistry 2006;39:978-83.

Transference Studies and CALIPER Sub-Studies

Higgins V, Chan MK, Nieuwesteeg M, Hoffman BR, Bromberg IL, Gornall D, Randell E, Adeli K. Transference of CALIPER pediatric reference intervals to biochemical assays on the Roche cobas 6000 and the Roche Modular P. Clinical Biochemistry  2015 Aug 19 [Epub ahead of print].

Araújo PA, Thomas D, Sadeghieh T, Bevilacqua V, Chan MK, Chen Y, Randell E, Adeli K. CLSI-based transference of the CALIPER database of pediatric reference intervals to Beckman Coulter DxC biochemical assays. Clinical Biochemistry 2015 Sep;48(13-14):870-80.

Abou El Hassan M, Stoianov A, Araújo PA, Sadeghieh T, Chan MK, Chen Y, Randell E, Nieuwesteeg M, Adeli K. CLSI-based transference of CALIPER pediatric reference intervals to Beckman Coulter AU biochemical assays. Clinical Biochemistry 2015 May 13 [Epub ahead of print].

Estey MP, Cohen AH, Colantonio DA, Chan MK, Marvasti TB, Randell E, Delvin E, Cousineau J, Grey V, Greenway D, Meng QH, Jung B, Bhuiyan J, Seccombe D, Adeli K. CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman, Ortho, Roche and Siemens Clinical Chemistry Assays: direct validation using reference samples from the CALIPER cohort. Clinical Biochemistry 2013;epub ahead of print.

Kyriakopoulou L, Yazdanpanah M, Colantonio DA, Chan MK, Daly CH, Adeli K. A sensitive and rapid mass spectrometric method for the simultaneous measurement of eight steroid hormones and CALIPER pediatric reference intervals. Clinical Biochemistry 2013;46:642-51.

Brinc D, Chan MK, Venner AA, Pasic MD, Colantonio D, Kyriakopolou L, Adeli K. Long-term stability of biochemical markers in pediatric serum specimens stored at -80°C: a CALIPER substudy. Clinical Biochemistry 2012 Apr 5.

Review Articles and Gap Analyses

Jung B, Adeli K. Clinical laboratory reference intervals in pediatrics: the CALIPER initiative. Clinical Biochemistry 2009;42:1589-95.

Schnabl K, Chan MK, Gong Y, Adeli K. Closing the gaps in pediatric reference intervals: the CALIPER initiative. Clinical Biochemist Reviews 2008;29:89-96.

Delvin EE, Laxmi Grey V, Vergee Z. Gap analysis of pediatric reference intervals related to thyroid hormones and the growth hormone-insulin growth factor axis. Clinical Biochemistry 2006;39:588-94.

Lepage N, Li D, Kavsak PA, Bamforth F, Callahan J, Dooley K, Potter M. Incomplete pediatric reference intervals for the management of patients with inborn errors of metabolism. Clinical Biochemistry 2006;39:595-9.

Mansoub S, Chan MK, Adeli K. Gap analysis of pediatric reference intervals for risk biomarkers of cardiovascular disease and the metabolic syndrome. Clinical Biochemistry 2006;39:569-87.