Morphea (Localized Scleroderma)
The Morphea Clinic is part of the Dermatology Department at The Hospital for Sick Children in Toronto. The clinic focuses on controlling the signs and symptoms and slowing the spread of the disease in children and adolescents.
Definition:
Morphea or localized scleroderma refers to a group of skin conditions consisting of an excessive accumulation of collagen in the skin and subdermal tissues. Several classifications have been proposed for this condition. Although there is no uniformity of agreement about its classification, clinicians agree that most patients can be grouped into plaque morphea, linear morphea or generalized morphea.
Morphea is a rare condition with an estimated incidence of 2.7 cases per 100,000.
Plaque morphea is most common presentation, accounting for 56% of all cases. The etiology and pathogenesis of this condition are still unclear. It is known that morphea patients have abnormal collagen fibers that become thickened and hyalinized. It has been postulated that autoimmunity, environmental factors, infection and trauma may trigger cytokine production and release that, in turn, are responsible for increased fibroblast and collagen synthesis.
Location of Clinic:
Clinic 7, Main Floor, Elm Wing
Our Specialists:
Co-Directors:
R. Laxer (Rheumatology)
E. Pope (Dermatology)
Coordinator:
Michelle Lee, RN
Holly Convery, RN
Occupational Therapist Practioner:
Chris O'Brien
How to Contact Us:
Please follow the referral process to book an appointment for the Morphea Clinic. If you are a SickKids patient please contact
416-813-7384 to book an appointment.