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Outcomes Research: Spine

OTHER AREAS:   HIP  |  MUSCULOSKELETAL TUMOURS  |  TRAUMA


Long-term Follow-up of Unit Rod Instrumentation in Spina Bifida Scoliosis

SickKids Principal Investigator: Dr. James G. Wright

A prospective comparative study to evaluate the long term outcomes and sequelae of instrumentation in patients with scoliosis and Spina Bifida Cystica, assess the complications associated with instrumentation, curve progression following instrumentation and  the quality of life of teenagers/young adults who underwent instrumentation for scoliosis as children.

Publications:
Khoshbin A, Vivas L, Law PW, Stephens D, Davis AM, Howard A, Jarvis JG, Wright JG. The long-term outcome of patients treated operatively and non-operatively for
scoliosis deformity secondary to spina bifida. Bone Joint J. 2014 Sep;96-B(9):1244-51. doi: 10.1302/0301-620X.96B9.33857. PubMed PMID: 25183598. See publication.

Patient-related Outcomes of Non-operative Management of High-grade Spondylolisthesis

SickKids Principal Investigator: Dr. Andrew Howard

The optimal management of high-grade spondylolisthesis in the growing child is controversial. Surgical intervention results in a >10% risk of complications with increased risk of neurological injury associated with slip reduction maneuvers. This study examines outcome measures in pediatric patients with high-grade spondylolisthesis managed either operatively or non-operatively.

Publications:
Lundine KM, Lewis SJ, Al-Aubaidi Z, Alman B, Howard AW. Patient outcomes in the operative and nonoperative management of high-grade spondylolisthesis inchildren. J Pediatr Orthop. 2014 Jul-Aug;34(5):483-9. doi:10.1097/BPO.0000000000000133. PubMed PMID: 24590330. See publications.

Validation of the Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD) Questionnaire in Children with Myelomeningocele and Duchennes Muscular Dystrophy

SickKids Principal Investigator: Dr. Unni Narayanan

The Caregiver Priorities & Child Health Index of Life with Disabilities (CPCHILD©) Questionnaire is a validated measure of health-related quality of life for children with severe disabilities. Using this tool which has been adopted worldwide, with multiple translated versions, investigators assess whether treatment makes a difference in the quality of life for these patients.

Publications:
See CPCHILD Questionnaire

Biomechanical Determinants of Surgical Outcomes in Adolescents with a Paediatric Spinal Deformity

SickKids Principal Investigator: Dr. Reinhard Zeller
Funding: CIHR

Generating new observations about the structure and function of the spine in adolescents diagnosed with idiopathic scoliosis before and after spinal instrumentation surgery is of great importance. This study measures the three-dimensional deformity and mobility of the spine utilising advanced imaging, opto-electronic and ambulatory monitoring technology.

Improving Education and Coping of Scoliosis Patients Undergoing Surgery and Their Families using E-health

SickKids Principal Investigator: Dr. James G. Wright
Funding: CIHR

Adolescent idiopathic scoliosis is a curvature of the spine sometimes resulting in back pain, respiratory problems and body image issues.  Surgery intervention if desired, involves placing rods, straightening, and fusing the spine sometimes associated with complications.  Using a website, we evaluate the influence streamlined scoliosis information has on patient and family decision making, social support and coping strategies.

Website: http://www.aboutkidshealth.ca/en/resourcecentres/scoliosis-teens/pages/default.aspx

Effectiveness of Direct Vertebral Derotation on Postoperative Apical Vertebral rotation in Adolescent Idiopathic Scoliosis

SickKids Principal Investigator: Dr. Reinhard Zeller

Postoperative vertebral rotation is known to be associated with suboptimal outcomes in scoliosis surgery. We use direct vertebral derotation technique in posterior spinal fusion for optimal rotational correction. This study explores its clinical importance by measuring postoperative improvement of apical vertebral rotation by 3D reconstruction using the novel low-dose imaging system, EOS.

Outcomes of Spinal Deformity Management in Cerebral Palsy (HARMS Study Foundation)

SickKids Principal Investigator: Dr. Unni Narayanan

International multi-centre study of the impact of spinal deformity in cerebral palsy on health-related quality of life and outcomes of management of spinal deformity in Cerebral Palsy.