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Adeli Lab

Refereed articles

Full Articles 2017

Zhang J, Zamani M, Thiele C, Taher J, Amir Alipour M, Yao Z, Adeli K. AUP1 (Ancient Ubiquitous Protein 1) Is a key determinant of hepatic very-low-density lipoprotein assembly and secretion. arterioscler Thromb Vasc Biol. 2017Apr;37(4):633-642.

Cagman Z, Bingol Ozakpinar O, Cirakli Z, Gedikbasi A, Ay P, Colantonio D, Uras AR, Adeli K, Uras F. Reference intervals for growth arrest-specific 6 protein in adults. Scand J Clin Lab Invest. 2017 Apr;77(2):109-114.

Taher J, Farr S, Adeli K. Central nervous system regulation of hepatic lipid and lipoprotein metabolism. Curr Opin Lipidol. 2017 Feb;28(1):32-38.

Full Articles 2016

Tate JR, Koerbin G, Adeli K. Opinion Paper: Deriving harmonised reference intervals - Global Activities. EJIFCC. 2016 Feb 9;27(1):48-65.

Anderson LN, Maguire JL, Lebovic G, Hanley AJ, Hamilton J, Adeli K, McCrindle BW, Borkhoff CM, Parkin PC, Birken CS. Duration of fasting, serum lipids, and metabolic profile in early childhood. J Pediatr. 2016 Oct 11.

Raizman JE, Shea J, Daly CH, Karbasy K, Ariadne P, Chen Y, Henderson T, Redmond S, Silverman S, Moore AM, Adeli K. Clinical impact of improved point-of-care glucose monitoring in neonatal intensive care using Nova StatStrip: evidence for improved accuracy, better sensitivity, and reduced test utilization. Clin Biochem. 2016 Aug 1;49(12):879-84.

Loverdos I, Swan MC, Shekherdimian S, Al-Rasheed AA, Schneider R, Fish JS, Ngan BY, Adeli K, Lowe ME, Singh VP, Sevilla WM, Langer JC, Gonska T. A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition.J Pediatr Surg Case Rep. 2015 May;3(5):223-226.

Kelishadi R, Marateb HR, Mansourian M, Ardalan G, Heshmat R, Adeli K. Pediatric-specific reference intervals in a nationally representative sample of Iranian children and adolescents: the CASPIAN-III study. World J Pediatr. 2016 Aug 1;12(3):335-42.

Bashiri A, Nesan D, Tavallaee G, Sue-Chue-Lam I, Chien K, Maguire GF, Naples M, Zhang J, Magomedova L, Adeli K, Cummins CL, Ng DS. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Biochim Biophys Acta. 2016 Apr 14:S1388-1981(16)30099.

Karbasy K, Lin DC, Stoianov A, Chan MK, Bevilacqua V, Chen Y, Adeli K. Pediatric reference value distributions and covariate-stratified reference intervals for 29 endocrine and special chemistry biomarkers on the Beckman Coulter immunoassay systems: a CALIPER study of healthy community children. Clin Chem Lab Med. 2016 Apr 1;54(4):643-57. 

Zamani M, Taher J, Adeli K. Complex role of autophagy in regulation of hepatic lipid and lipoprotein metabolism. J Biomed Res. 2016 Mar 3;30.

Farr S, Taher J, Adeli K. Central nervous system regulation of intestinal lipid and lipoprotein metabolism. Curr Opin Lipidol. 2016 Feb 1;27(1):1-7. 

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L. Full list of authors Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016 Jan 1;12(1):1-222.

Ali SA, Al-Jazrawe M, Ma H, Whetstone H, Poon R, Farr S, Naples M, Adeli K, Alman BA. Regulation of cholesterol homeostasis by hedgehog signaling in osteoarthritic cartilage. Arthritis Rheumatol. 2016 Jan 1;68(1):127-37.

Higgins V, Chan MK, Nieuwesteeg M, Hoffman BR, Bromberg IL, Gornall D, Randell E, Adeli K. Transference of CALIPER pediatric reference intervals to biochemical assays on the Roche cobas 6000 and the Roche Modular P. Clin Biochem. 2016 Jan 1;49(1-2):139-49.

Full Articles 2015

Abou El Hassan M, Stoianov A, Araújo PA, Sadeghieh T, Chan MK, Chen Y, Randell E, Nieuwesteeg M, Adeli K. CLSI-based transference of CALIPER pediatric reference intervals to Beckman Coulter AU biochemical assays. Clin Biochem. 2015 Nov 1;48(16-17):1151-9.

Kelly J, Raizman JE, Bevilacqua V, Chan MK, Chen Y, Quinn F, Shodin B, Armbruster D, Adeli K. Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents. Clin Chim Acta. 2015 Oct 23;450:196-202.

Hsieh J, Trajcevski KE, Farr SL, Baker CL, Lake EJ, Taher J, Iqbal J, Hussain MM, Adeli K. Glucagon-Like peptide 2 (GLP-2) stimulates postprandial chylomicron production and postabsorptive release of intestinal triglyceride storage pools via induction of nitric oxide signaling in male hamsters and mice. Endocrinology. 2015 Oct 1;156(10):3538-47.

Gorgani-Firuzjaee S, Khatami S, Adeli K, Meshkani R. SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells. Biochem Biophys Res Commun. 2015 Sep 4;464(4):1028-33.

Lino M, Farr S, Baker C, Fuller M, Trigatti B, Adeli K. Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 1;309(5):G350-9.

Raizman JE, Quinn F, Armbruster DA, Adeli K. Pediatric reference intervals for calculated free testosterone, bioavailable testosterone and free androgen index in the CALIPER cohort. Clin Chem Lab Med. 2015 Sep 1;53(10):e239-43.

Teodoro-Morrison T, Kyriakopoulou L, Chen YK, Raizman JE, Bevilacqua V, Chan MK, Wan B, Yazdanpanah M, Schulze A, Adeli K. Dynamic biological changes in metabolic disease biomarkers in childhood and adolescence: A CALIPER study of healthy community children. Clin Biochem. 2015 Sep 1;48(13-14):828-36.

Gorgani-Firuzjaee S, Adeli K, Meshkani R. Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells. Biochem Biophys Res Commun. 2015 Aug 21;464(2):441-6.

Higgins V, Chan MK, Nieuwesteeg M, Hoffman BR, Bromberg IL, Gornall D, Randell E, Adeli K. Transference of CALIPER pediatric reference intervals to biochemical assays on the Roche cobas 6000 and the Roche Modular P. Clin Biochem. 2015 Aug 19.

Adeli K, Raizman JE, Chen Y, Higgins V, Nieuwesteeg M, Abdelhaleem M, Wong SL, Blais D. Complex biological profile of hematologic markers across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clin Chem. 2015 Aug 1;61(8):1075-86.

Adeli K, Higgins V, Nieuwesteeg M, Raizman JE, Chen Y, Wong SL, Blais D. Complex reference values for endocrine and special chemistry biomarkers across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clin Chem. 2015 Aug 1;61(8):1063-74.

Adeli K, Higgins V, Nieuwesteeg M, Raizman JE, Chen Y, Wong SL, Blais D. Biochemical marker reference values across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clin Chem. 2015 Aug 1;61(8):1049-62.

Xiao C, Dash S, Morgantini C, Adeli K, Lewis GF. Gut peptides are novel regulators of intestinal lipoprotein secretion: experimental and pharmacological manipulation of lipoprotein metabolism. Diabetes. 2015 Jul 1;64(7):2310-8.

Farr S, Baker C, Naples M, Taher J, Iqbal J, Hussain M, Adeli K. Central nervous system regulation of intestinal lipoprotein metabolism by glucagon-like peptide-1 via a brain-gut axis. Arterioscler Thromb Vasc Biol. 2015 May 1;35(5):1092-100.

Loverdos I, Swan MC, Shekherdimian S, Al-Rasheed AA, Schneider R, Fish JS, Ngan BY, Adeli K, Lowe ME, Singh VP, Sevilla WM, Langer JC, Gonska T. A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition. J Pediatr Surg Case Rep. 2015 May 1;3(5):223-226.

Devgun MS, Chan MK, El-Nujumi AM, Abara R, Armbruster D, Adeli K. Clinical decision limits for interpretation of direct bilirubin - A CALIPER study of healthy multiethnic children and case report reviews. Clin Biochem. 2015 Jan 1;48(1-2):93-96.

Full Articles 2014

Taher J, Baker CL, Cuizon C, Masoudpour H, Zhang R, Farr S, Naples M, Bourdon C, Pausova Z, Adeli K. GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance. Mol Metab. 2014 Dec 1;3(9):823-33.

Bevilacqua V, Chan MK, Chen Y, Armbruster D, Schodin B, Adeli K. Pediatric population reference value distributions for cancer biomarkers and covariate-stratified reference intervals in the CALIPER cohort. Clin Chem. 2014 Dec 1;60(12):1532-42.

Kavsak PA, Rezanpour A, Chen Y, Adeli K. Assessment of the 99th or 97.5th percentile for cardiac troponin I in a healthy pediatric cohort. Clin Chem. 2014 Dec 1;60(12):1574-6.

Markle JG, Frank DN, Adeli K, von Bergen M, Danska JS. Microbiome manipulation modifies sex-specific risk for autoimmunity. Gut Microbes. 2014 Jul 1;5(4):485-93.

Neuman G, Nulman I, Adeli K, Koren G, Colantonio DA, Helldén A. Implications of serum creatinine measurements on GFR estimation and vancomycin dosing in children. J Clin Pharmacol. 2014 Jul 1;54(7):785-91.

McNamara PJ, Engelberts D, Finelli M, Adeli K, Kavanagh BP. Vasopressin improves survival compared with epinephrine in a neonatal piglet model of asphyxial cardiac arrest. Pediatr Res. 2014 Jun 1;75(6):738-48.

Erek-Toprak A, Bingol-Ozakpinar O, Karaca Z, Cikrikcioglu MA, Hursitoglu M, Uras AR, Adeli K, Uras F. Association of plasma growth arrest-specific protein 6 (Gas6) concentrations with albuminuria in patients with type 2 diabetes. Ren Fail. 2014 Jun 1;36(5):737-42.

Adeli K. Closing the gaps in pediatric reference intervals: an update on the CALIPER project. Clin Biochem. 2014 Jun 1;47(9):737-9. 

Su Q, Baker C, Christian P, Naples M, Tong X, Zhang K, Santha M, Adeli K. Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis. Am J Physiol Endocrinol Metab. 2014 Jun 1;306(11):E1264-73.

Raizman JE, Cohen AH, Teodoro-Morrison T, Wan B, Khun-Chen M, Wilkenson C, Bevilaqua V, Adeli K. Pediatric reference value distributions for vitamins A and E in the CALIPER cohort and establishment of age-stratified reference intervals. Clin Biochem. 2014 Jun 1;47(9):812-5.

Bailey D, Perumal N, Yazdanpanah M, Al Mahmud A, Baqui AH, Adeli K, Roth DE. Maternal-fetal-infant dynamics of the C3-epimer of 25-hydroxyvitamin D. Clin Biochem. 2014 Jun 1;47(9):816-22.

Bailey D, Bevilacqua V, Colantonio DA, Pasic MD, Perumal N, Chan MK, Adeli K. Pediatric within-day biological variation and quality specifications for 38 biochemical markers in the CALIPER cohort. Clin Chem. 2014 Mar 1;60(3):518-29.

Shaw JL, Cohen A, Konforte D, Binesh-Marvasti T, Colantonio DA, Adeli K. Validity of establishing pediatric reference intervals based on hospital patient data: A comparison of the modified Hoffmann approach to CALIPER reference intervals obtained in healthy children. Clin Biochem. 2014 Feb 1;47(3):166-72. 

Kyriakopoulou L, Yazdanpanah M, Colantonio D, Adeli K. In reply. Clin Chem. 2014 Feb 1;60(2):419-23.

Farr S, Taher J, Adeli K. Glucagon-like peptide-1 as a key regulator of lipid and lipoprotein metabolism in fasting and postprandial states. Cardiovasc Hematol Disord Drug Targets. 2014 Jan 1;14(2):126-36.

Full Articles 2013

Sniderman AD, Qi Y, Ma CI, Wang RH, Naples M, Baker C, Zhang J, Adeli K, Kiss RS. Hepatic cholesterol homeostasis: is the low-density lipoprotein pathway a regulatory or a shunt pathway? Arterioscler Thromb Vasc Biol. 2013 Nov 1;33(11):2481-90.

Yazdanpanah M, Bailey D, Walsh W, Wan B, Adeli K. Analytical measurement of serum 25-OH-vitamin D₃, 25-OH-vitamin D₂ and their C3-epimers by LC-MS/MS in infant and pediatric specimens. Clin Biochem. 2013 Sep 1;46(13-14):1264-71. 2012 Dec 23. pii: S0009-9120(12)00703-5. doi: 10.1016/j.clinbiochem.2012.11.030.

Rutledge AC, Qiu W, Zhang R, Urade R, Adeli K. Role of cysteine-protease CGHC motifs of ER-60, a protein disulfide isomerase, in hepatic apolipoprotein B100 degradation. Arch Biochem Biophys. 2013 Sep 1;537(1):104-12.

Bailey D, Colantonio D, Kyriakopoulou L, Cohen AH, Chan MK, Armbruster D, Adeli K. Marked biological variance in endocrine and biochemical markers in childhood: establishment of pediatric reference intervals using healthy community children from the CALIPER cohort. Clin Chem. 2013 Sep 1;59(9):1393-405. 2013 May 1.

Estey MP, Cohen AH, Colantonio DA, Chan MK, Marvasti TB, Randell E, Delvin E, Cousineau J, Grey V, Greenway D, Meng QH, Jung B, Bhuiyan J, Seccombe D, Adeli K. CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman, Ortho, Roche and Siemens clinical chemistry assays: direct validation using reference samples from the CALIPER cohort. Clin Biochem. 2013 Sep 1;46(13-14):1197-219. 2013 Apr 8. pii: S0009-9120(13)00114-8. doi: 10.1016/j.clinbiochem.2013.04.001.

Mokhtari RB, Kumar S, Islam SS, Yazdanpanah M, Adeli K, Cutz E, Yeger H. Combination of carbonic anhydrase inhibitor, acetazolamide, and sulforaphane, reduces the viability and growth of bronchial carcinoid cell lines. BMC Cancer. 2013 Aug 8;13:378.

Konforte D, Shea JL, Kyriakopoulou L, Colantonio D, Cohen AH, Shaw J, Bailey D, Chan MK, Armbruster D, Adeli K. Complex biological pattern of fertility hormones in children and adolescents: a study of healthy children from the CALIPER cohort and establishment of pediatric reference intervals. Clin Chem. 2013 Aug 1;59(8):1215-27. 2013 May 1.

Dekker MJ, Baker C, Naples M, Samsoondar J, Zhang R, Qiu W, Sacco J, Adeli K. Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. Atherosclerosis. 2013 May 1;228(1):98-109. 2013 May;228(1):98-109. doi: 10.1016/j.atherosclerosis.2013.01.041. Epub 2013 Feb 10.

Kyriakopoulou L, Yazdanpanah M, Colantonio DA, Chan MK, Daly CH, Adeli K. A sensitive and rapid mass spectrometric method for the simultaneous measurement of eight steroid hormones and CALIPER pediatric reference intervals. Clin Biochem. 2013 May 1;46(7-8):642-51. 2013 May;46(7-8):642-51. doi: 10.1016/j.clinbiochem.2013.01.002. Epub 2013 Jan 18.

Lu J, Ji J, Meng H, Wang D, Jiang B, Liu L, Randell E, Adeli K, Meng QH. The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovasc Diabetol. 2013 Apr 5;12:58. 2013 Apr 5;12:58. doi: 10.1186/1475-2840-12-58.

Christian P, Sacco J, Adeli K. Autophagy: Emerging roles in lipid homeostasis and metabolic control. Biochim Biophys Acta. 2013 Apr 1;1831(4):819-24. Epub 2012 Dec 26.

Bailey D, Veljkovic K, Yazdanpanah M, Adeli K. Analytical measurement and clinical relevance of vitamin D(3) C3-epimer. Clin Biochem. 2013 Feb 1;46(3):190-6.

Shaw JL, Binesh Marvasti T, Colantonio D, Adeli K. Pediatric reference intervals: challenges and recent initiatives. Crit Rev Clin Lab Sci. 2013 Feb 1;50(2):37-50. 2013 May 8.

Hein GJ, Baker C, Hsieh J, Farr S, Adeli K. GLP-1 and GLP-2 as yin and yang of intestinal lipoprotein production: evidence for predominance of GLP-2-stimulated postprandial lipemia in normal and insulin-resistant states. Diabetes. 2013 Feb 1;62(2):373-81. 2013 Feb;62(2):373-81. doi: 10.2337/db12-0202. Epub 2012 Oct 1.

Pinkosky SL, Filippov S, Srivastava RA, Hanselman JC, Bradshaw CD, Hurley TR, Cramer CT, Spahr MA, Brant AF, Houghton JL, Baker C, Naples M, Adeli K, Newton RS. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan 1;54(1):134-51.

Full Articles 2012

Hsieh J, Adeli K. Regulation of intestinal chylomicron production by glucagon-like peptides. Cardiovasc Hematol Disord Drug Targets. 2012 Dec 1;12(2):92-7. 2012 Dec;12(2):92-7.

Pasic MD, Colantonio DA, Chan MK, Venner AA, Brinc D, Adeli K. Influence of fasting and sample collection time on 38 biochemical markers in healthy children: a CALIPER substudy. Clin Biochem. 2012 Oct 1;45(15):1125-30. 2012 Oct;45(15):1125-30. doi: 10.1016/j.clinbiochem.2012.07.089. Epub 2012 Jul 20.

Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2012 Sep 1;32(9):2104-12. 2012 Sep;32(9):2104-12. doi: 10.1161/ATVBAHA.111.241463. Epub 2012 Jul 12.

Brinc D, Chan MK, Venner AA, Pasic MD, Colantonio D, Kyriakopolou L, Adeli K. Long-term stability of biochemical markers in pediatric serum specimens stored at -80 °C: a CALIPER Substudy. Clin Biochem. 2012 Jul 1;45(10-11):816-26. 2012 Jul;45(10-11):816-26. doi: 10.1016/j.clinbiochem.2012.03.029. Epub 2012 Apr 5.

Hager L, Li L, Pun H, Liu L, Hossain MA, Maguire GF, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins CL, Connelly PW and Ng DS. Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice. J Biol Chem. 2012 Jun 8. 2012 Jun 8;287(24):20755-68. doi: 10.1074/jbc.M112.340919. Epub 2012 Apr 12.

Sacco J, Adeli K. MicroRNAs: emerging roles in lipid and lipoprotein metabolism. Curr Opin Lipidol. 2012 Jun 1;23(3):220-5. 2012 Jun;23(3):220-5. doi: 10.1097/MOL.0b013e3283534c9f.

Yue JT, Mighiu PI, Naples M, Adeli K and Lam TK. Glycine normalizes hepatic triglyceride-rich VLDL secretion by triggering the CNS in high-fat fed rats. Circ Res. 2012 May 11. 2012 May 11;110(10):1345-54. doi: 10.1161/CIRCRESAHA.112.268276. Epub 2012 Apr 3.

Colantonio DA, Kyriakopoulou L, Chan MK, Daly CH, Brinc D, Venner AA, Pasic MD, Armbruster D, Adeli K. Closing the gaps in pediatric laboratory reference intervals: a CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children. Clin Chem. 2012 May 1;58(5):854-68. 2012 May;58(5):854-68. doi: 10.1373/clinchem.2011.177741. Epub 2012 Feb 27.

Naples M, Baker C, Lino M, Iqbal J, Hussain MM and Adeli K. Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance. Am J Physiol Gastrointest Liver Physiol. 2012 May 1. 2012 May 1;302(9):G1043-52. doi: 10.1152/ajpgi.00250.2011. Epub 2012 Feb 16.

Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC Jr, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F. Full list of authors. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr 1;8(4):445-544. 2012 Apr;8(4):445-544.

Shi SY, Martin RG, Duncan RE, Choi D, Lu SY, Schroer SA, Cai EP, Luk CT, Hopperton KE, Domenichiello AF, Tang C, Naples M, Dekker MJ, Giacca A, Adeli K, Wagner KU, Bazinet RP and Woo M. Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. J Biol Chem. 2012 Mar 23. 2012 Mar 23;287(13):10277-88. doi: 10.1074/jbc.M111.317453. Epub 2012 Jan 24.

Farr S, Adeli K. Incretin-based therapies for treatment of postprandial dyslipidemia in insulin-resistant states. Curr Opin Lipidol. 2012 Feb 1;23(1):56-61. 2012 Feb;23(1):56-61. doi: 10.1097/MOL.0b013e32834d68f0.

Kelishadi R, Poursafa P, de Ferranti SD, Schwandt P, Adeli K, Onat A, Gidding SS. Pediatric metabolic syndrome: from prevention to treatment. Cholesterol. 2012 Jan 1;2012:374168. 2012;2012:374168. doi: 10.1155/2012/374168. Epub 2012 Nov 11.

Full Articles 2011

Adeli K. Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules. Am J Physiol Endocrinol Metab. 2011 Dec;301(6):E1051-64.

Wengle JG, Hamilton JK, Manlhiot C, Bradley TJ, Katzman DK, Sananes R, Adeli K, Birken CS, Abadilla AA, McCrindle BW. The ‘Golden Keys’ to health - a healthy lifestyle intervention with randomized individual mentorship for overweight and obesity in adolescents. Paediatr Child Health. 2011 Oct;16(8):473-8.

Xiao C, Hsieh J, Adeli K, Lewis GF. Gut-liver interaction in triglyceride-rich lipoprotein metabolism. Am J Physiol Endocrinol Metab. 2011 Sep;301(3):E429-46.
Hayes JA, Forrest CR, Walsh W, Pétroz GC, Adeli K, Bissonnette B. Continuous bupivacaine infusion post-iliac crest bone graft harvesting in pediatric cleft surgery: role and comparison with ketorolac. Cleft Palate Craniofac J. 2011 Sep;48(5):532-7.

Karimian Pour N, Adeli K. Insulin silences apolipoprotein B mRNA translation by inducing intracellular traffic into cytoplasmic RNA granules. Biochemistry. 2011 Aug 16;50(32):6942-50.

Hayashi AA, Webb J, Choi J, Baker C, Lino M, Trigatti B, Trajcevski KE, Hawke TJ, Adeli K. Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G326-37.
Wang H, Zhang J, Qiu W, Han GS, Carman GM, Adeli K. Lipin-1γ isoform is a novel lipid droplet-associated protein highly expressed in the brain. FEBS Lett. 2011 Jun 23;585(12):1979-84.

Qiu W, Zhang J, Dekker MJ, Wang H, Huang J, Brumell JH, Adeli K. Hepatic autophagy mediates endoplasmic reticulum stress-induced degradation of misfolded apolipoprotein B. Hepatology. 2011 May;53(5):1515-25.

Boros CA, Bradley TJ, Cheung MM, Bargman JM, Russell JL, McCrindle BW, Adeli K, Hamilton J, Silverman ED. Early determinants of atherosclerosis in paediatric systemic lupus erythematosus. Clin Exp Rheumatol. 2011 May;29(3):575-81.

Adeli K. Closing the gaps in pediatric reference intervals: the CALIPER initiative. Clin Biochem. 2011 May;44(7):480-2.

Warnakula S, Hsieh J, Adeli K, Hussain MM, Tso P, Proctor SD. New insights into how the intestine can regulate lipid homeostasis and impact vascular disease: frontiers for new pharmaceutical therapies to lower cardiovascular disease risk. Can J Cardiol. 2011 Mar;27(2):183-91.

Lu J, Randell E, Han Y, Adeli K, Krahn J, Meng QH. Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy. Clin Biochem. 2011 Mar;44(4):307-11.

Wong DT, George K, Wilson J, Manlhiot C, McCrindle BW, Adeli K, Kantor PF. Effectiveness of serial increases in amino-terminal pro-B-type natriuretic peptide levels to indicate the need for mechanical circulatory support in children with acute decompensated heart failure. Am J Cardiol. 2011 Feb 15;107(4):573-8.
MohammadTaghvaei N, Meshkani R, Taghikhani M, Larijani B, Adeli K. Palmitate enhances protein tyrosine phosphatase 1B (PTP1B) gene expression at transcriptional level in C2C12 skeletal muscle cells. Inflammation. 2011 Feb;34(1):43-8.

Lu J, Zello GA, Randell E, Adeli K, Krahn J, Meng QH. Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis. Clin Chim Acta. 2011 Jan 30;412(3-4):286-91.

Xi L, Xiao C, Bandsma RH, Naples M, Adeli K, Lewis GF. C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases. Hepatology. 2011 Jan;53(1):127-35.

Full Articles 2010

Kelishadi R, Hashemipour M, Adeli K, Tavakoli N, Movahedian-Attar A, Shapouri J, Poursafa P, Rouzbahani A. Effect of zinc supplementation on markers of insulin resistance, oxidative stress, and inflammation among prepubescent children with metabolic syndrome. Metab Syndr Relat Disord. 2010 Dec 1;8(6):505-10.

Levin A, DeSouza C, Zaarour C, Walsh W, Chan MK, Verjee Z, McIntyre S, Adeli K. Pediatric reference intervals for lymphocyte vitamin C (ascorbic acid). Clin Biochem. 2010 Dec 1;43(18):1411-4.

Blasutig IM, Jung B, Kulasingam V, Baradaran S, Chen Y, Chan MK, Colantonio D, Adeli K. Analytical evaluation of the VITROS 5600 Integrated System in a pediatric setting and determination of pediatric reference intervals. Clin Biochem. 2010 Sep 1;43(13-14):1039-44.

Kulasingam V, Jung BP, Blasutig IM, Baradaran S, Chan MK, Aytekin M, Colantonio DA, Adeli K. Pediatric reference intervals for 28 chemistries and immunoassays on the Roche cobas 6000 analyzer--a CALIPER pilot study. Clin Biochem. 2010 Sep 1;43(13-14):1045-50.

Dong B, Wu M, Li H, Kraemer FB, Adeli K, Seidah NG, Park SW, Liu J. Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. J Lipid Res. 2010 Jun 1;51(6):1486-95.

Wong DM, Webb JP, Malinowski PM, Xu E, Macri J, Adeli K. Proteomic profiling of intestinal prechylomicron transport vesicle (PCTV)-associated proteins in an animal model of insulin resistance (94 char). J Proteomics. 2010 May 7;73(7):1291-305. 2010; 73(7): 1291-305.

O’Gorman CS, Simoneau-Roy J, Pencharz P, MacFarlane J, MacLusky I, Narang I, Adeli K, Daneman D, Hamilton J. Sleep-disordered breathing is increased in obese adolescents with craniopharyngioma compared with obese controls. J Clin Endocrinol Metab. 2010 May 1;95(5):2211-8.

Meng QH, Adeli K, Zello GA, Porter WH, Krahn J. Elevated lactate in ethylene glycol poisoning: True or false? Clin Chim Acta. 2010 Apr 2;411(7-8):601-4.

Rutledge AC, Su Q, Adeli K. Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly. Biochem Cell Biol. 2010 Apr 1;88(2):251-67.

Rutledge AC, Su Q, Adeli K. Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly. Biochem Cell Biol. 2010 Apr 1;88(2):251-67.

Hsieh J, Longuet C, Baker CL, Qin B, Federico LM, Drucker DJ, Adeli K. The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice. Diabetologia. 2010 Mar 1;53(3):552-61.

Bakhtiyari S, Meshkani R, Taghikhani M, Larijani B, Adeli K. Protein tyrosine phosphatase-1B (PTP-1B) knockdown improves palmitate-induced insulin resistance in C2C12 skeletal muscle cells. Lipids. 2010 Mar 1;45(3):237-44.

Simoneau-Roy J, O’Gorman C, Pencharz P, Adeli K, Daneman D, Hamilton J. Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma. Clin Endocrinol (Oxf). 2010 Mar 1;72(3):364-70.