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Drugs and Breastfeeding

Who We Are

Photo of Dr. Shinya Ito

Dr. Shinya Ito, MD, FRCPC
Division Head, Clinical Pharmacology & Toxicology, Department of Paediatrics
Senior Scientist, Translational Medicine, The Hospital for Sick Children

Dr. Shinya Ito is the Principal Investigator of the DLAC project. He is a clinician-scientist at SickKids and an attending physician in the paediatric drug consultation service, Motherisk clinic and the DART (Drug Allergy Reaction & Toxicology) clinic. Dr. Ito’s research is mainly focused on mechanisms of drug transport in breast milk and long-term side effects of drugs on children including how genes influence drug responses (pharmacogenomics). 


Photo of Dr David Colantonio

Dr. David Colantonio, PhD, DABCC, FCACB
Clinical Biochemist, Department of Paediatric Laboratory Medicine, The Hospital for Sick Children
Assistant Professor, Laboratory Medicine & Pathobiology, University of Toronto

Dr. David Colantonio is the co-investigator of the DLAC project. He is a clinical biochemist who oversees clinical diagnostic and toxicology testing at SickKids. Dr. Colantonio’s research interest focuses on pharmacokinetics and therapeutic drug monitoring/toxicology with application towards investigating the expression of drugs into breast milk and the risk these drugs may pose to the nursing infant.


Photo of Dr Andrea Edington

Dr. Andrea Edginton, PhD
Associate Professor, Programmatic Assesment Officer, University of Waterloo

Dr. Andrea Edginton’s research focuses on the development and application of physiologically-based pharmacokinetic (PBPK) models and simulation techniques in both the areas of pharmaceuticals and human health risk assessment. Her research examines how the physiology of sub-populations such as children and patients with disease (e.g. obesity, liver cirrhosis) affect the pharmacokinetics of drugs and how this information can be integrated into PBPK models for the optimization of drug therapy. Of special interest is the physiological scaling of evaluated PBPK models from adults to children as a means to predict drug pharmacokinetics and quantify appropriate dosing regimens for clinical trials in children. Evaluation techniques for large and small molecule PBPK models are also an area of research.


Picture of Sarah Delaney

Sarah Delaney, M.Sc.
PhD Candidate, Department of Pharmacology and Toxicology, University of Toronto
Division of Clinical Pharmacology & Toxicology, The Hospital for Sick Children

Sarah Delaney is involved in the method development and analysis of drugs in breast milk. Her research interests include: drug safety during breastfeeding and mechanisms of drug-nutrient interactions in the mammary gland.


Photo of Sholah Ghayoori

Sholeh Ghayoori, MD, CCRP
Clinical Research Project Coordinator, Division of Clinical Pharmacology & Toxicology, The Hospital for Sick Children

Sholeh Ghayoori coordinates the project operations and is responsible for study logistics, participant recruitment, bio-specimen transfer and handling, data management, and monitoring of day-to-day performance of research activities. The study participants will be in direct contact with the study coordinator.