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Farhat Lab
Farhat Lab

Abnormal urinary bladder

A variety of bladder diseases such as cancer or abnormal bladder development may affect the proper function of the urinary bladder and these, in turn, cause renal dysfunction, urinary incontinence and ultimately necessitate urinary bladder augmentation or replacement. Currently the gastrointestinal tract serves as a substitute tissue for the urinary bladder and is the standard biograft in the adult and paediatric population. On the other hand, the reported problems with incorporating bowel into the urinary tract, such as infection, stone formation, metabolic abnormalities secondary to absorption of urine, perforation and carcinogenesis have ignited interest in bladder tissue engineering for bladder regeneration.

Click to watch animation of an abnormal urinary bladder