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Bagli Lab
Bagli Lab

Publications

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Aitken KJ, Tolg C, Panchal T, Leslie B, Yu J, Elkelini M, Sabha N, Tse DJ, Lorenzo AJ, Hassouna M, Bägli DJ. Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle. Am J Pathol. 2010 Jan;176(1):304-19. Epub 2009 Dec 17.

Aitken KJ, Bägli DJ. The bladder extracellular matrix. Part I: architecture, development and disease. Nature Reviews Urology, 2009. 6: 596-611.

Aitken KJ, Bägli DJ. The bladder extracellular matrix. Part II: regenerative applications. Nature Reviews Urology, 2009. 6: 612-621.

Estrada CR, Adam RM, Eaton SH, Bägli DJ, Freeman MR. Inhibition of EGFR signaling abrogates smooth muscle proliferation resulting from sustained distension of the urinary bladder. Lab Invest. 2006 Oct 16 [Epub ahead of print].

Aitken KJ, Block G, Lorenzo A, Herz D, Sabha N, Dessouki O, Fung F, Szybowska M, Craig L, Bägli DJ. Mechanotransduction of extracellular signal-regulated kinases 1 and 2 mitogen-activated protein kinase activity in smooth muscle is dependent on the extracellular matrix and regulated by matrix metalloproteinases. Am J Pathol, 2006. 169(2): p. 459-70.

Sabha N, Aitken K, Lorenzo AJ, Szybowska M, Jairath A, Bägli DJ. Matrix metalloproteinase-7 and epidermal growth factor receptor mediate hypoxia-induced extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase activation and subsequent proliferation in bladder smooth muscle cells. In Vitro Cell Dev Biol Anim, 2006. 42(5): p. 124-33.

Halachmi S, Aitken KJ, Szybowska M, Sabha N, Dessouki S, Lorenzo A, Tse D, Bägli DJ. Role of signal transducer and activator of transcription 3 (STAT3) in stretch injury to bladder smooth muscle cells. Cell Tissue Res, 2006. 326(1): p. 149-58.

Brown AL, Ringuette MJ, Prestwich GD, Bägli DJ, Woodhouse KA. Effects of hyaluronan and SPARC on fibroproliferative events assessed in an in vitro bladder acellular matrix model. Biomaterials. 2006 Jul;27(20):3825-35.

Adam RM, Eaton SH, Estrada C, Nimgaonkar A, Shih S-C, Smith Lois EH, Kohane IS, Bägli D, Freeman MR. Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. Physiol Genomics. 2004 Dec 15;20(1):36-44.

Brown AL, Brook-Allred TT, Waddell JE, White J, Werkmeister JA, Ramshaw JA, Bägli DJ, Woodhouse KA. Bladder acellular matrix as a substrate for studying in vitro bladder smooth muscle-urothelial cell interactions. Biomaterials. 2004 Feb;26(5):529-43.

Herz DB, Aitken K, Bägli DJ. Collagen directly stimulates bladder smooth muscle cell growth in vitro: regulation by extracellular regulated mitogen activated protein kinase. J Urol. 2003 Nov;170(5):2072-6

Hafez AT, Bägli DJ, Bahoric A, Aitken K, Smith CR, Herz D, Khoury AE. Aerosol transfer of bladder urothelial and smooth muscle cells onto demucosalized colonic segments: a pilot study. J Urol. 2003 Jun;169(6):2316-9

Upadhyay J, Aitken KJ, Damdar C, Bolduc S, Bägli DJ. Integrins expressed with bladder extracellular matrix after stretch injury in vivo mediate bladder smooth muscle cell growth in vitro. J Urol. 2003 Feb;169(2):750-5.

A detailed list of Dr. Bägli's publications is available on Pub Med. »»