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Paediatric Laboratory Medicine

S-100B Protein

Clinical Significance

S100 has been studied for use as a biochemical marker for central nervous system pathology. Numerous studies in the literature have suggested the clinical usefulness of measuring this protein in cerebrospinal fluid, and in recent years, serum S100B has been reported as a useful marker for early detection of metastases of melanoma and cerebral complications from head injury, cardiac surgery, and acute stroke.

Test Name

S-100B Protein

Alternate Name/ Synonym

Protein S-100B

Test Code



Biochemistry- Test Development Multiplex


Automated Immunoassay Analyzer

Turn Around Time

Batch testing (50 samples)


Brain injuries marker

Specimen Type


Minimum Specimen Requirements

500 uL


Send frozen

Special Requirements

* For research purposes only.

Approval is required

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Phone: 416-813-7200
Phone: 1-855-381-3212