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Paediatric Laboratory Medicine

Broad Spectrum Drug Screen

Background

Screen and confirmation for a wide variety of individual drugs by LC-MS/MS (Liquid chromatography - Mass spectrometry/ Mass spectrometry). Currently there are over 1400 drugs in the Broad Spectrum Drug Library (Parent & Metabolites)

Includes many of the drug classes normally done by immunoassay: Amphetamine/Methamphetamine, Cocaine metabolite, Ecstasy, Methadone/Methadone metabolite, Opiates, Oxycodone, PCP, Trcyclics.

Reported as "Not Detected" or "Positive" based on a minimum concentration of drug being present in the urine to allow for proper identification of the drug by matching the MS (Mass spectrometry) spectra of the unknown compound to the Mass Spectrometry Spectra in the library. Phone the Toxicology Laboratory at 416-813-5906, to check on the availability of any specific drug if not listed here.

Test Name

Broad Spectrum Drug Screen

Alternate Name/ Synonym

Wide Range of Drug Classes

Test Code

TX1U, TX1B, TX1O

Division

Toxicology

Method

LC-MS/MS

External Proficiency Testing

QMPLS, CAP

Turn Around Time

Daily, Stat

Specimen Type

Urine, Blood (Serum or plasma), Miscellaneous Fluid(s)*

Minimum Specimen Requirements

2.0 mL

Storage/Transportation

4°C (transport with a cool pack if possible)

Approval is not required

CPT Codes

80100

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

Therapeutic Range

Not Detected

Critical Values

Drug Dependent