Facebook Pixel Code
Section banner image
Paediatric Laboratory Medicine

Bloom Syndrome Testing

Clinical Significance

An increase in sister chromatid exchange frequency is observed in Bloom syndrome patients.

Test Name

Bloom Syndrome Testing

Alternate Name/ Synonym

Sister Chromatid Exchange (SCE) Analysis

Division

Cytogenetics

Method

3 day culture with addition of Bromodeoxyuridine; Specialized staining for SCE

External Proficiency Testing

Internal Proficiency Testing

Turn Around Time

4 Weeks

Disease/Condition

Bloom Syndrome

Specimen Type

Peripheral Blood

Minimum Specimen Requirements

3-6mL (3 mL minimum for neonates)

Storage/Transportation

Maintain at room temperature. Do not refrigerate or freeze.

Special Requirements

Collect in sodium heparin tube

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

Interpretation

Provided