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Paediatric Laboratory Medicine

FISH - Whole Chromosome Paints - Peripheral Blood

Clinical Significance

Used to help characterize chromosome rearrangements

Test Name

FISH - Whole Chromosome Paints - Peripheral Blood

Gene Name

  • All chromosomes

Division

Cytogenetics

Method

3 day PHA-stimulated thymidine-synchronized culture; FISH (Fluorescence in situ hybridization)

External Proficiency Testing

CAP
QMPLS

Turn Around Time

4 weeks for routine
5-9 working days for expedite

Disease/Condition

Chromosome rearrangements

Specimen Type

Peripheral Blood

Minimum Specimen Requirements

Blood at room temperature in sodium heparin
Volume: 0-3 months  1-3 mL
                3 months-12 years: 3-6 mL
                12 years - adult: 6 mL

Storage/Transportation

Maintain at room temperature. Do not refrigerate or freeze.

Special Requirements

Collect in sodium heparin tube

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

Interpretation

Provided