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Paediatric Laboratory Medicine

Detection of IL3-IgH; t(5;14) (q31;q32)

Clinical Significance

IL3-IgH fusion gene is detected in B lineage acute lymphoblastic leukemia with t(5;14) (q31;q32) which is seen in a rare subset of acute lymphocytic leukemia with associated with eosiniophilia.

Test Name

Detection of IL3-IgH; t(5;14) (q31;q32)

Gene Name

IL3-IgH fusion gene

Division

Haematopathology- Molecular Haematology

Method

RT PCR (Real-time polymerase chain reaction) (end point)

Turn Around Time

2-3 working days

Disease/Condition

ALL (Acute lymphocytic leukemia)

Specimen Type

Peripheral Blood, Bone Marrow Aspirate

Minimum Specimen Requirements

2 mL

Storage/Transportation

Room Temperature (on ice if shipping takes more than 48 hrs).

Special Requirements

Sample to be collected in EDTA or Sodium citrate(preservative). Please call Laboratory prior to shipping your samples.

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212