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Paediatric Laboratory Medicine

Detection of RBM15-MKL1; t(1;22)(p13;q13)

Clinical Significance

RBM15-MKL1 fusion gene; t(1;22)(p13;q13) is found in infants with acute megakaryoblastic leukemia.

Test Name

Detection of RBM15-MKL1; t(1;22)(p13;q13)

Gene Name

  • RBM15 -MKL1 fusion gene


Haematopathology- Molecular Haematology


RT PCR (Real-time polymerase chain reaction) (end point)

Turn Around Time

2-3 working days


AMKL (Acute megakaryoblastic leukemia)

Specimen Type

Peripheral Blood, Bone Marrow Aspirate

Minimum Specimen Requirements

2 mL


Room Temperature (on ice if shipping takes more than 48 hrs).

Special Requirements

Sample to be collected in EDTA  or Sodium citrate(preservative) Please call Laboratory prior to shipping your samples

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Phone: 416-813-7200
Phone: 1-855-381-3212