A new study by Canadian researchers may pave the way for more effective treatment of an aggressive and deadly type of brain tumour, known as ETMR/ETANTR. The tumour, which is seen only in children under four, is almost always fatal, despite aggressive treatment. The study proposes a new model for how this brain tumour develops and suggests possible targets to investigate for novel therapies. These findings, recently published in Nature Genetics, also shed new light on the complex process of early brain development. The study was led by the Research Institute of the McGill University Health Centre (RI-MUHC), McGill University, and The Hospital for Sick Children (SickKids), and funded by the Cancer Research Society.
New research shows that preterm babies with slower brain development as they reach their due dates are more likely to have delayed cognitive, language and motor development at 18 months of age. The researchers also found that preterm babies with significant injury to the brain’s white matter were more likely to have slower motor development as toddlers. Brain injuries in preterm babies are most often linked to lack of brain blood flow or to inflammation.
For the past two years, warnings regarding the possible link between a commonly used anti-nausea and vomiting drug ondansetron and heart arrhythmias have been a source of uncertainty in emergency departments. New research from The Hospital for Sick Children (SickKids) and the University of Calgary’s Alberta Children’s Hospital Research Institute helps to clarify the actual risk of ondansetron administration and cardiac arrhythmias in both children and adults. The study is published in the December issue of Annals of Emergency Medicine.