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About Sickkids
About SickKids

Sylvain Baruchel, MD

The Hospital for Sick Children
Senior Medical Advisor, Innovative Therapeutic Trials

Research Institute
Senior Associate Scientist, Emeritus
Research Institute

University of Toronto
Professor, Emeritus

Phone: 416-813-7795
Fax: 416-813-5327
Email: sylvain.baruchel@sickkids.ca

Brief Biography

Dr Baruchel has been a leader in clinical trials in oncology at SickKids as the director of the clinical trial program for 20 years as the founder   the “New Agent and Innovative Therapy Program”   Dr. Baruchel is nationally and internationally recognized for his work in oncology  drug  development. He is  the founder and  former  chair  the  Canadian C17 developmental therapeutic network and current chair of the National Cancer Institute of Canada Paediatric Investigational New Drug committee.

He is current  a  senior medical advisor for innovative therapies and his current role is to advise the deparment of pediatric’s   chair and  chair of the research institute on Matters related to innovative therapeutics.  Dr Baruchel collaborates with Dr. Rulan Parekh, the Associate Chair of Clinical Research in leading and developing the infrastructure and processes needed to implement and  conduct SickKids sponsored  innovative therapeutic trials using  novel agents, or devices throughout SickKids.  He is  leading a working group within the Clinical Research Secretariat, an advisory group on clinical research, to develop a pipeline for clinical trials and acts as a resource for the hospital and research institute Principal Investigators looking at early phase trial development.

Dr Baruchel is also a pediatric expert consultant for Canadian Agency for Drugs and Technologies in Health (CADTH). CADTH  is an independent, not-for-profit organization responsible for providing health care decision-makers with objective evidence to help make informed decisions about the optimal use of health technologies.

Academic Background

Dr. Baruchel received his MD degree in 1977 from the Rene Descartes University in Paris and was recruited to the Haematology/Oncology Division at the Montreal Children's Hospital in Canada in 1988 where he was Director of the Sickle Cell/Thalassemia Comprehensive Care Programs and Medical Coordinator of the Hematology/Oncology Inpatient Unit.

Research Interests

  • Translational medicine
  • Clinical pharmacology
  • Experimental therapies in children, Preclinical Proof of principle and Early phase clinical trials
  • Surrogate markers.
  • Regulatory affairs


In 2010, Baruchel was awarded the Légion D'honneur (equivalent to the Order of Canada) from the French government for his work done in the last ten years in the field of rehabilitation and increasing self-esteem in childhood cancer and more importantly for philanthropic activity, fundraising, and developing the concept of Adventure Therapy.


A detailed list of Dr. Baruchel's publications is available on PubMed.