About Sickkids
About SickKids

Gregory H. Borschel, MD, FACS, FAAP

The Hospital for Sick Children
Surgeon
Plastic and Reconstructive Surgery

Research Institute
Associate Scientist
Neurosciences & Mental Health

University of Toronto
Assistant Professor
Departments of Surgery and Biomaterials, and Biomedical Engineering


Phone: 416-813-7654 Ext. 228197
Fax: 416-813-6637
e-mail: gregory.borschel@sickkids.ca

For more information, visit:

Borschel Lab »»

Brief Biography

“I am privileged to work with a fabulous group of individuals at SickKids dedicated to helping kids with complex problems.”

Dr. Greg Borschel has been a full-time staff surgeon at SickKids since 2009. His practice focuses on the care of children with nerve injuries, as well as hand surgery and microsurgery. Borschel is a co-director of the Facial Palsy Clinic with Dr. Ronald Zuker. He is also a co-director of the Nerve Injury Clinic in the Division of Plastic and Reconstructive Surgery.

Borschel completed medical school at The Johns Hopkins University before training in plastic and reconstructive surgery at the University of Michigan, graduating in 2005. During his residency in Ann Arbor he completed a research fellowship in neuromuscular tissue engineering. Following residency he completed a fellowship in paediatric plastic and reconstructive surgery at SickKids. He then accepted a position in the Division of Plastic and Reconstructive Surgery at Washington University in St. Louis and was recruited back to SickKids in 2009.

Borschel is an assistant professor in the Division of Plastic and Reconstructive Surgery in the Department of Surgery at the University of Toronto and an associate member of the Institute of Medical Science, University of Toronto. He is an associate scientist in the SickKids Research Institute with an appointment in the Physiology & Experimental Medicine Program. Borschel is also an assistant professor in the Institute of Biomaterials and Biomedical Engineering at the University of Toronto.

Borschel’s laboratory is focused on nerve regeneration and ways to improve functional outcomes following peripheral nerve injury. The group has strong collaborations in the Institute of Biomaterials and Biomedical Engineering at University of Toronto, as well as abroad. The group is using growth factors, stem cells, advanced biomaterials and novel surgical paradigms to improve nerve regeneration. The group is currently supported by federal and provincial funding mechanisms, as well as external foundations, grants and gifts. If interested in donating to Borschel's research efforts please visit http://www.sickkidsfoundation.com/donate/.

Borschel has authored or coauthored 35 peer-reviewed publications, two textbooks and over 200 presentations at scientific meetings. He was the recipient of the 2007 American Association of Plastic Surgeons Academic Scholar Award and the 2009 American College of Surgeons Fellowship for the Study of Trauma and Critical Care for his work in growth factor mediated peripheral nerve regeneration.

Borschel is an international authority on nerve injury and regeneration and has participated in educational meetings and scientific symposia around the world.

Academic Background

Degrees
B.Sc.: Chemistry and Biology, Emory University, Atlanta, USA, 1993
MD: Johns Hopkins University School of Medicine, 1997

Residency
Plastic and Reconstructive Surgery, University of Michigan, 1997-2005

Fellowships
Neuromuscular Tissue Engineering Research, University of Michigan, 2001-3
Paediatric Plastic and Reconstructive Surgery, The Hospital for Sick Children, 2005-6

Certifications
Diplomate of the American Board of Plastic Surgery, 2007
Fellow of the American College of Surgeons, 2009
Fellow of the American Association of Pediatrics, 2008

MEMBERSHIPS AND ASSOCIATIONS
American Society for Peripheral Nerve
American College of Surgeons
Plastic Surgery Research Council
Tissue Engineering and Regenerative Medicine Society International
American Society of Plastic Surgery
Canadian Medical Protective Association
College of Physicians and Surgeons of Ontario

Learning Intersts

CLINICAL AREA OF INTEREST

  • Nerve injury and regeneration
  • Microsurgery
  • Hand surgery

RESEARCH ACTIVITIES

  • Nerve injury and regeneration

External Funding

  • Plastic Surgery Educational Foundation Pilot Research Grant: A transgenic rat expressing GFP in peripheral nerves
  • Plastic Surgery Educational Foundation Pilot Research Grant Award Number 137077: Decellularized nerve allografts and motor nerve regeneration
  • BJHF/ICTS Clinical and Translational Research Funding Program planning grant: Radiologic predictors of functional outcome in newborn brachial plexus injury
  • American College of Surgeons C. James Carrico Faculty of Research Fellowship for the Study of Trauma and Critical Care: Controlled growth factor delivery for motor nerve injury
  • American Society for Surgery of the Hand: GDNF: The influence on motor nerve regeneration in a rat femoral nerve model
  • American Society for the Peripheral Nerve:  A novel transgenic rat expressing green fluorescent protein (GFP) in peripheral nerve

Achievements

2008 
Specialty Fellow, American Academy of Pediatrics

2009 
American Society for Peripheral Nerve Research Award. January 11, 2009, Maui, Hawaii.

American College of Surgeons C. James Carrico Faculty Research Fellowship for the Study of Trauma and Critical Care. 
July 1, 2009.

Fellow, American College of Surgeons

Publications

Controlled delivery of glial cell line-derived neurotrophic factor enhances motor nerve regeneration.  Moore AM, Wood MD, Chenard K, Hunter DA, Mackinnon SE, Sakiyama-Elbert SE, Borschel GH.  J Hand Surg Am. 2010 Dec;35(12):2008-17.

Upper and lower extremity nerve injuries in pediatric missile wounds: a selective approach to management.
Stoebner AA, Sachanandani NS, Borschel GH.  Pediatr Surg Int. 2010 Sep 21.

A new model for facial nerve research: the novel transgenic Thy1-GFP rat.  Magill CK, Moore AM, Borschel GH, Mackinnon SE.  Arch Facial Plast Surg. 2010 Sep-Oct;12(5):315-20.

Fibrin matrices with affinity-based delivery systems and neurotrophic factors promote functional nerve regeneration.
Wood MD, MacEwan MR, French AR, Moore AM, Hunter DA, Mackinnon SE, Moran DW, Borschel GH, Sakiyama-Elbert SE.
Biotechnol Bioeng. 2010 Aug 15;106(6):970-9.

A selective approach to treatment of ulnar polydactyly: preventing painful neuroma and incomplete excision.
Mullick S, Borschel GH.  Pediatr Dermatol. 2010 Jan-Feb;27(1):39-42.


The 'Ten Test': application and limitations in assessing sensory function in the paediatric hand.

Sun HH, Oswald TM, Sachanandani NS, Borschel GH.  J Plast Reconstr Aesthet Surg. 2010 Nov;63(11):1849-52. Epub 2010 Jan 27.

Obstetrical brachial plexus palsy.  Borschel GH, Clarke HM.  Plast Reconstr Surg. 2009 Jul;124(1 Suppl):144e-155e. Review.

A Three-Subunit Latissimus Dorsi Muscle Free Flap for Single-Stage Coverage of the Hand and Three Adjacent Fingers.
Borschel GH.  Hand (N Y). 2009 Jun 30.  

Simplified Negative Pressure Wound Therapy in Pediatric Hand Wounds.  Kasukurthi R, Borschel GH.  Hand (N Y). 2009 Jun 27.  

The short- and long-term effects of Seprafilm on peripheral nerves: a histological and functional study.  Magill CK, Tuffaha SH, Yee A, Luciano JP, Hunter DA, Mackinnon SE, Borschel GH.  J Reconstr Microsurg. 2009 Jul;25(6):345-54.  

Processed allografts and type I collagen conduits for repair of peripheral nerve gaps.  Whitlock EL, Tuffaha SH, Luciano JP, Yan Y, Hunter DA, Magill CK, Moore AM, Tong AY, Mackinnon SE, Borschel GH.  Muscle Nerve. 2009 Jun;39(6):787-99.

Limitations of conduits in peripheral nerve repairs.  Moore AM, Kasukurthi R, Magill CK, Farhadi HF, Borschel GH, Mackinnon SE.  Hand (N Y). 2009 Jun;4(2):180-6.  

Affinity-based release of glial-derived neurotrophic factor from fibrin matrices enhances sciatic nerve regeneration.
Wood MD, Moore AM, Hunter DA, Tuffaha S, Borschel GH, Mackinnon SE, Sakiyama-Elbert SE.  Acta Biomater. 2009 May;5(4):959-68.  

The impact of motor and sensory nerve architecture on nerve regeneration.  Moradzadeh A, Borschel GH, Luciano JP, Whitlock EL, Hayashi A, Hunter DA, Mackinnon SE.  Exp Neurol. 2008 Aug;212(2):370-6.  

Controlled release of glial-derived neurotrophic factor from fibrin matrices containing an affinity-based delivery system.
Wood MD, Borschel GH, Sakiyama-Elbert SE.   Biomed Mater Res A. 2009 Jun 15;89(4):909-18.