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Cardiac Transplant Program

Heart Centre Biobank

Brief Biography

Dr. Anne Dipchand began her medical career by receiving her MD from the University of Toronto in 1992. Interested in science from a young age, she chose cardiology as her subspecialty in her second year of residency, and decided that continuing to work and learn at SickKids as she had done for her internship was the best way to continue her education. She now gives back to both institutions that have brought her so far, as an Associate Professor with the University of Toronto, and as a Staff Cardiologist and head of the Heart Transplant program at SickKids.
Dr. Dipchand loves to spend time with her own children, three young girls, and travel when she is not busy with all of her responsibilities at The Hospital for Sick Children and the University.
Dr. Dipchand enjoys practicing at SickKids because the default is asking questions, and helping to move her field forward. With so much progress still to be made, the hospital is one place that always strives to move towards the best patient care and outcomes.

Clinical Care Activities 

• Transplant
• Heart failure
• Echocardiography and general cardiography

Research Interests

• Transplant: optimizing post-transplant outcomes; high risk transplants
• Heart failure: investigating outcomes of paediatric cardiomyopathies
• Echocardiography: non-invasive assessment for transplant and coronary artery disease (dobutamine stress echocardiography)

External Funding

Clinical and laboratory evaluation of acute rejection, myocyte growth, repair and oxidative stress following de novo cardiac transplant: a comparison between Tacrolimus- and Cyclosporine-based immunprophylactic regimens with mycophenolic acid therapeutic drug monitoring. Dipchand AI, Pollock BarZiv S, Allain-Rooney T, Kantor PF: Astellas Pharma Canada Inc. (2006-2008)

Cyclosporine C2 Monitoring in Pediatric Heart Transplant Recipients: A Pilot Study. Dipchand AI, Allain-Rooney, T: Novartis Pharmaceuticals Inc. (2006-2007)

Perioperative use of thymoglobulin in paediatric heart transplant recipients. Dipchand AI, Pollock-BarZiv SM, Allain-Rooney T, Kantor PF: Genzyme Canada (2006-2007)

HLA Sensitization: Prevalence and Impact of Alloantibodies in Pediatric Heart Transplant Recipients. Dipchand AI, Pollock-Barziv, S; McCrindle BM: Paediatric Consultants (2007-2008)

Outcome of Pediatric Patients with Cardiomyopathy: a multicentre review of pediatric patients listed for transplant in the Pediatric Heart Transplant Study Group. Dipchand AI, Hsu D, Naftel D: Children's Cardiomyopathy Foundation. (2007-2008)

Achievements

2006-James C. Fallis Teaching Award
Division of Paediatric Emergency Medicine, Hospital for Sick Children.

2003-Award for Clinical Excellence in Paediatric Medical Care
Department of Paediatrics, University of Toronto, Hospital for Sick Children.

1999-Mycophenolic acid levels in paediatric heart transplant recipients receiving mycophenolate mofetil American Society of Transplantation, Young Investigators Award
18th Annual Meeting, Scientifc Sessions Program.

1996-Ondaatje Teaching Award(Award for Teaching Excellence), Hospital for Sick Children.

1992-Cody Gold Medal, University of Toronto, Faculty of Medicine.

Publications

Pollock-BarZiv SM, McCrindle BW, West LJ, Dipchand AI: Waiting before birth: outcomes after fetal listing for heart transplantation. American Journal of Transplantation 2008: 8: pp 412-8.

Han RK, Gurofsky RC, Lee KJ, Dipchand AI, Williams WG, Smallhorn JF, McCrindle BW: Outcome and growth potential of left heart structures after neonatal intervention for aortic valve stenosis. Journal of the American College of Cardiology 2007: 50: pp 2406-14.

Pollock-BarZiv SM, McCrindle BW, West LJ, Manhliot C, Vanderliet M, Dipchand AI: Competing outcomes after neonatal and infant wait-listing for heart transplantation. Journal of Heart and Lung Transplantation 2007: 26: pp 980-5. SRI

Pollock-BarZiv SM, den Hollander N, Ngan B, Kantor P, McCrindle B, Dipchand AI: Pediatric Heart Transplantation in Human Leukocyte Antigen Sensitized Patients: Evolving Management and Assessment of Intermediate-Term Outcomes in a High-Risk Population. Circulation 2007: 116: pp I:172-178.

Pollock Bar-Ziv SM, McCrindle B, West LJ, Edgell D, Coles J, VanArsdell G, Bohn D, Peres R, Campbell A, Dipchand AI: Outcomes of pediatric patients waitlisted for heart transplantation from extracorporeal membrane oxygenation (ECMO) support. ASAIO Journal 2007: 53: pp 97-102.

Dipchand AI: Heart transplantation: literature review 2004-2005. Pediatric Transplantation 2006: 10(3): pp 277-287.

Dipchand AI, Cecere R, Delgado D, Dore A, Giannetti N, Haddad H, Howlett J, LeBlanc M, Leduc L, Marelli A, Perron J, Poirier N, Ross H: Canadian Consensus on cardiac transplantation in pediatric and adult congenital heart disease patients 2004: Executive Summary. Canadian Journal of Cardiology 2005: 21(13): pp 1145-1148.

Lobach NE, Pollock-BarZiv SM, West LJ, Dipchand AI: Sirolimus immunosuppression in pediatric heart transplant recipients: a single centre experience. Journal of Heart and Lung Transplantation 2005: 24(2): pp 184-189.

Rosenthal D, Chrisant MR, Edens E, Mahony L, Canter C, Colan S, Dubin A, Lamour J, Ross R, Shaddy R, Addonizio L, Beerman L, Berger S, Bernstein D, Blume E, Boucek M, Checchia P, Dipchand AI, Drummond-Webb J, Fricker J, Friedman R, Hallowell S, Jaquiss R, Mital S, Pahl E, Pearce B, Rhodes L, Rotondo K, Rusconi P, Scheel J, Pal Singh T, Towbin J: International society for heart and lung transplantation: practice guidelines for management of heart failure in children. Journal of Heart and Lung Transplantation 2004: 23(12): pp 1313-1333.

Dipchand AI, Pietra B, McCrindle BW, Rosebrook-Bicknell HL, Boucek MM: Mycophenolate acid levels in pediatric heart transplant recipients receiving mycophenolate mofetil. Journal of Heart and Lung Transplantation 2001: 20(10): pp 1035-1043.