Facebook Pixel Code
About Sickkids
About SickKids

Benjamin T. Dunkley, Ph.D.

The Hospital for Sick Children
MEG Clinical Associate
Diagnostic Imaging

Research Institute
Associate Scientist
Neurosciences & Mental Health

University of Toronto
Assistant Professor
Dept. of Medical Imaging


Phone: 416-813-7654 ext. 328817
Email: ben.dunkley@sickkids.ca
Alternate Contact: Seetha Sriharan
Alternate Phone: 416-813-5175
Alternate Email: seetha.sriharan@sickkids.ca

Brief Biography

Dr. Benjamin Dunkley studied at Cardiff University, UK, where he completed his PhD thesis on the role of cortical oscillations in oculomotor control and vision motion perception using MEG. He then completed a postdoc at York University, Toronto, where he studied transaccadic integration and spatiotopic representation in the dorsal visual stream. This was followed by a postdoc at The Hospital for Sick Children (SickKids) with Drs. Margot Taylor and Elizabeth Pang, studying functional connectivity in clinical populations, including PTSD and concussion, during cognition and task-free resting-state. He now works at SickKids as a Clinical Associate, using MEG to study changes in brain connectivity related to a variety of neurological and psychiatric conditions.
 

Research Interests

  • MEG brain imaging: cortical oscillations, neural synchronisation, functional connectivity, computational and systems neuroscience
  • Clinical neurophysiology: Post-traumatic stress disorder (PTSD), Mild Traumatic brain injury (mTBI; concussion)
  • Cognition, perception and action: Attention, cognitive control, vision, eye movements, sensory-motor integration

Broadly speaking, Dunkley's current research involves studying the role of brain oscillations and functional connectivity underlying cognition and perception in clinical populations. He is particularly interested in how psychiatric and neurological conditions impact communication in the brain mediated by neural oscillations. These phenomena are studied using magnetoencephalography, or MEG, which allows the measurement of minute electrical currents generated in the brain during the act of performing a cognitive task.

Publications

Preprints                      

Dunkley, BT, Urban, K, Da Costa, L, Bethune, A, Pang, EW & Taylor, MJ. Oscillatory default mode network coupling is associated with concussion symptom severity, bioRxiv

Safar, K, Sato, J, Ruocco, AC, Korenblum, MS, O'Halpin, H, & Dunkley, BT. Disrupted socio-emotional neural circuitry in adolescents with borderline personality traits, psyArXiv

2018

Da Costa, L, Shah-Basak, PP, Dunkley, BT, Robertson, A, & Pang, EW. Memory encoding and retrieval deficits in good outcome aneurysmal subarachnoid patients, Frontiers in Human Neuroscience

Dunkley, BT, Wong, S, Jetly, J, & Taylor, MJ. Post-traumatic stress disorder and chronic hyperconnectivity in emotional processing, NeuroImage: Clinical

Bardouille, T, Power, L, LaLancette, M, Bishop, R, Beyea, S, Taylor, MJ & Dunkley, BT. Variability and bias between magnetoencephalography systems in non-invasive localization of the primary somatosensory cortex, Clinical Neurology and Neurosurgery, 171:63-69

Dunkley, BT, Urban, K, Da Costa, L, Bethune, A, Pang, EW & Taylor, MJ. Oscillatory default mode network coupling is increased following concussion, Frontiers in Neurology, 9

Shah-Basak, P, Urbain, C, Wong, S, da Costa, L, Pang, EW, Dunkley, BT & Taylor, MJ. Concussion alters the functional brain processes of visual attention and working memory, Journal of Neurotrauma, 35(2):267-277

2017                                

Sussman, D., Da Costa, L., Robertson, A., Chakravarty, M., Taylor, M.J. & Dunkley, B.T. Concussion induces focal and widespread neuromorphological changes, Neuroscience Letters, 650, 52-59, doi: 10.1016/j.neulet.2017.04.026

Mennella, R., Leung, R.C., Taylor, M.J. & Dunkley, B.T. Disconnection from others in autism is more than just a feeling: Whole-brain neural synchrony in adults during implicit processing of emotional faces, Molecular Autism, 18(7), doi: 10.1186/s13229-017-0123-2

2016 

Da Costa, L., Dunkley, B.T., Bethune, A., Robertson, A., MacDonald, M., Taylor, M.J. & Pang, E.W. Feasibility of magnetoencephalography after endovascular treatment of ruptured intracranial aneurysms, Frontiers in Neurology, doi: dx.doi.org/10.3389/fneur.2016.00163
                                                                                 
Da Costa, L, Dunkley, B.T., Bethune, A., Robertson, A., MacDonald, M. & Pang, E.W. Increased frontal lobe activation following aneurysmal subarachnoid hemorrhage, Stroke, 47(9). doi: 0.1161/STROKEAHA.116.013786

Dunkley, B.T., Baltaretu, B. & Crawford, J.D. Trans-saccadic Interactions in human parietal and occipital cortex during the retention and comparison of object orientation, Cortex,82:263-76. doi: 10.1016/j.cortex.2016.06.012

Dunkley, B.T., Doesburg, S.M., Sedge, P.A., Jetly, R., Shek, P.N., Pang, E.W.& Taylor, M.J. Alpha hyperconnectivity and atypical memory processing in soldiers with PTSD, Journal of Neuroimaging in Psychiatry and Neurology, 1(2):54-63

Sussman, D., Pang, E.W., Jetly, R., Dunkley, B.T.* & Taylor, M.J. Neuroanatomical features in soldiers with Post-Traumatic Stress Disorder, BMC Neuroscience,17(13):1-11, doi: 10.1186/s12868-016-0247-x

Dunkley, B.T, Pang, E.W., Sedge, P. A., Jetly, R., Doesburg, S. M., & Taylor, M. J. Threatening faces induce fear circuitry hypersynchrony in soldiers with post-traumatic stress disorder, Heliyon,2(1). doi: 10.1016/j.heliyon.2015.e00063

Misic, B., Dunkley, B.T., Sedge, P.A., Da Costa, L., Fatima, Z., Berman, M.G., Doesburg, S.M., McIntosh, A.R., Grodecki, R.J., Jetly, R., Pang, E.W. & Taylor, M.J. Posttraumatic stress constrains the dynamic repertoire of neural activity, Journal of Neuroscience, 36(2), 419-431. doi: 10.1523/JNEUROSCI.1506-15.2016

2015 

Pang, E.W., Dunkley, B.T., Doesburg, S.M., Da Costa, L. & Taylor, M. J. Reduced brain connectivity and mental flexbility in mild traumatic brain injury, Annals of Clinical and Translational Neurology, doi: 10.1002/acn3.280

Dunkley, B.T., Freeman, T.C.A., Muthukumaraswamy, S.D. & Singh, K.D. Evidence that smooth pursuit velocity, not eye position, modulates alpha and beta oscillations in human middle temporal cortex, Human Brain Mapping, 36(12): 5220-5232. doi: 10.1002/hbm.23006

Dunkley, B.T. Differential intrinsic coupling modes in psychological and physical trauma, Frontiers in Psychiatry,6:140. doi: http://dx.doi.org/10.3389/fpsyt.2015.00140

Dunkley, B.T., Doesburg, S.M., Jetly, R., Sedge, P.A., Pang, E.W. & Taylor, M.J. Characterising intra- and inter-intrinsic network synchrony in combat-related post-traumatic stress disorder. Psychiatry Research: Neuroimaging, 234(2):72-81. doi: http://dx.doi.org/10.1016/j.pscychresns.2015.09.002

Dunkley, B.T., Sedge, P.A., Doesburg, S.M., Grodecki, R. J., Jetly, R., Shek, P.N., Taylor, M.J. & Pang, E.W. Theta, mental flexibility and PTSD: connecting in the parietal cortex, PLOS ONE, 10(4). doi: 10.1371/journal.pone.0123541

Dunkley, B.T., Da Costa, L., Bethune, A., Jetly, R., Pang, E.W., Taylor, M.J. & Doesburg, S.M. Low-frequency connectivity is associated with mild traumatic brain injury. NeuroImage: Clinical, 7, 611-621. doi: 10.1016/j.nicl.2015.02.020

2014 

Dunkley, B.T., Doesburg, S.M., Sedge, P.A., Grodecki, R.J., Shek, P.N., Pang, E.W. & Taylor, M.J.
Resting-state hippocampal connectivity correlates with symptom severity in post-traumatic stress disorder, NeuroImage: Clinical, 5, 377–384. doi: 10.1016/j.nicl.2014.07.017

Allen, C., Dunkley, B.T., Muthukumaraswamy, S.D., Edden, R., Evans, C. J., Sumner, P., Singh, K.D. & Chambers, C.D. Enhanced awareness followed reversible inhibition of human visual cortex: A combined TMS, MRS and MEG study, PLOS ONE, 9(6):1-20. doi: 10.1371/journal.pone.0100350

Dymond, D., Lawrence, N.S., Dunkley, B.T.,  Yuen, S.L., Hinton, E.C., Dixon, M.R., Cox, W.M., Hoon, A.E., Munnelly, A., Muthukumaraswamy, S.D. & Singh, K.D. Almost winning: Induced MEG theta power in insula and orbitofrontal cortex increases during gambling near-misses and is associated with BOLD signal and gambling severity, NeuroImage, 91(1):210-219. doi: 10.1016/j.neuroimage.2014.01.019

2013 

Dunkley, B.T., Freeman, T.C.A., Muthukumaraswamy, S.D. & Singh, K.D. Cortical oscillatory changes in human Middle Temporal Cortex underlying smooth pursuit eye movements, Human Brain Mapping, 34(4):837-851. doi: 10.1002/hbm.21478