Brief Biography

Dr. deVeber is Director of the Children's Stroke Program and a paediatric neurologist in the Division of Neurology at the Hospital for Sick Children, Toronto, Canada. She is Professor of Paediatrics at the University of Toronto and Senior Scientist, Child Health Evaluative Sciences Program in the Research Institute, Hospital for Sick Children.  Her research focuses on stroke in newborns and children, defining the frequency, causes, treatments and outcomes of paediatric stroke.  She initiated and directs several large multi-centre collaborative studies including the Canadian Paediatric Ischemic Stroke Registry and International Paediatric Stroke Study (IPSS), a large international study of childhood stroke with over 2,500 enrolled children at over 35 enrolling centres spanning 18 countries in Asia, Europe, North and South America.  The central organization and database reside at the Hospital for Sick Children.  In 2009, National Institutes of Health (NIH) funded Dr. deVeber as dual principal investigator with H. Fullerton in the USA to study childhood infection and stroke within the IPSS in a seven year study.

Clinical Care Activities 

Children with stroke.

Areas of Specialty 

Paediatric Stroke

Academic Background

Research:
Hamilton Civic Hospitals Research Center and McMaster University, Hamilton, 1995-07-01 - 1998-07-01

Clinical: Pediatric Neurorehabilitation
Spaulding Rehabilitation Hospital, Electromyography, Mass. General Hospital, 1990-07-01 - 1991-07-01

Research Interests

The Children’s Stroke Project and Canadian Paediatric Ischemic Stroke Registry:

The Children’s Stroke Project, a number of inter-related studies of childhood stroke caused by blood clots. The Canadian Paediatric Ischemic Stroke Registry has studied stroke in more than 800 infants and children at the 16 children’s hospitals in Canada. At least 3.2 per 100,000 children per year suffer stroke in Canada. Our studies in HSC children are defining important causes for stroke including chicken pox and anticardiolipin antibodies, a clotting problem. We are also studying treatments and outcomes. The HSC Stroke Outcome Study has found disability in over 40%, recurrent events in 20% and seizures and headaches in another 25%. Finally we are developing multinational studies of treatments for childhood stroke with collaborators in the UK and USA.

Research Activities

Safety and feasibility of low molecular weight heparin in neonates; a population based cohort study of incidence, health care utilization and health outcomes in children with stroke.

Further Research Activities 

International clinical trials in childhood stroke.

Achievements

July 2001 - July 2006 "Stroke Investigator Award" Research Scholar
July 1998 - July 2001 "Stroke Investigator Award": Phase II, Junior Faculty
July 1995 - 1998 Heart and Stroke Foundation of Ontario "Stroke Investigator Award" - Research Fellow

Publications

Golomb M, MacGregor D, Domi T, Armstrong D, McCrindle B, Mayank S, and deVeber G. Presumed pre-or perinatal arterial ischemic stroke: risk factors and outcomes. Annals of Neurology 2001; 50(2):163 - 168

deVeber G, Andrew M, Adams C et al for The Canadian Pediatric Ischemic Stroke Study Group. Cerebral sinovenous thrombosis in childhood. NEJM 2001: Aug 9; 345:417-423

Askalan R, Laughlin S, Mayank S, Chan A, MacGregor D, Curtis R, Meaney B, deVeber G. Chicken pox and stroke in childhood: A study of frequency and causation. Stroke 2001; 32:1257-1262

Lanthier S, Lortie A, Michaud J, Laxer R, Jay V, deVeber G. Isolated angiitis of the CNS in children. Neurology 2001; 56:837-842

deVeber G, MacGregor D, Curtis R and Mayank S. Neurological outcome in survivors of childhood arterial ischemic stroke and sinovenous thrombosis. J Child Neurol 2000;15:316-324

Lanthier S, Carmant L, David M, Larbrisseau A, de Veber G. Stroke in children: the coexistence of multiple risk factors predicts poor outcome. Neurology 2000; 54(2):371-8