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About Sickkids
About SickKids

Elizabeth Harvey, MD, FRCP(C)

The Hospital for Sick Children
Staff Physician
Nephrology

University of Toronto
Associate Professor
Faculty of Medicine, Department of Paediatrics


Phone: 416-813-5082
Fax: 416-813-6271
Email: elizabeth.harvey@sickkids.ca

Brief Biography

Dr. Elizabeth Harvey received her medical degree from Memorial University of Newfoundland in 1982. She completed her Pediatric training at Memorial University and Dalhousie University, followed by a
Pediatric Nephrology Fellowship at the Hospital for Sick Children, University of Toronto (1986-88).  She
joined the Division of Nephrology at The Hospital for Sick Children in 1988.  

Academic Background

Degrees, Diplomas and Certifications

1987 FRCPC, Fellow Royal College of Physicians and Surgeons of Canada, Pediatrics

1982 M.D., Memorial University of Newfoundland, Newfoundland, Canada

1980 Bachelor Med Science, Memorial University of Newfoundland, Newfoundland, Canada

Research Interests

Clinical Interests

  • Staff physician in the Division of Nephrology (The Hospital for Sick Children)
  • Chronic kidney disease (CKD)
  • Acute and chronic renal replacement therapy (hemodialysis, peritoneal dialysis, CRRT)
  • Pediatric Kidney Stones
  • Systemic Lupus Erythematosis (Clinician in the joint nephrology/rheumatology SLE clinic)
  • Sleep disorders in dialysis and chronic kidney disease

Research Interests

Chronic Kidney Disease (CKD) is a life-long condition.  Currently there are only treatments - conservative management with medications, followed by dialysis and transplantation - but there is no cure.  Chronic Kidney disease care, and in particular dialysis,  represents a substantial burden of care for patients and families, and CKD impacts on longevity, with known premature death from cardiovascular disease.  My clinical research focus seeks to treat remediable factors that may help to alter longevity (eg omega 3 fatty acids for hypertriglyceridemia), to improve the tolerance and efficacy of dialysis therapy (eg: reducing hypotension during dialysis, finding strategies to improve dialytic solute removal such as phosphate) and to identify and if possible remediate factors which impact the quality of life of patients on dialysis (eg: identifying sleep disorders).

Rare inherited causes of kidney stones in children create significant morbidity for the patient (pain, loss of time from school, need to take medications) and may cause irreversible kidney damage.  I am collaborating with Canadian colleagues to look for claudin mutations in patients with hypercalciuria, and with the Rare Kidney Stone Consortium to facilitate diagnosis and management of rare inherited kidney stone disorders, and to contribute to knowledge of the natural history of these diseases.

External Funding

May 2012 - May 2013        

Co-Investigator.
Pediatric Sleep Disorders in Children Receiving Dialysis. Pediatric Consultants Grant, SickKids.
Principal Investigator: Reshma Amin; Co-Investigator(s): Elizabeth Harvey, Indra Narang and Khamisa Al-Mokali
$ 9,520 CAD

May 2008 – Jan 2012       

Principal Investigator (Jun 2011 - 2012)
Co-Investigator (May 2008-2010)
Omega 3 Fatty Acid Supplementation to Treat Hypertriglyceridemia in Children with Chronic Kidney Disease. Hospital for Sick Children, Complementary & Alternative Health Care & Paediatrics Research Grants Competition
Principal Investigator(s): Elizabeth Harvey, Donna Secker. Co-Investigator(s): Elizabeth Harvey, Annette Vigneux, Rulan S Parekh.
$ 48,993 CAD  Active enrollment of patients

Achievements

Selected

2013 POWER Teaching Award (Academic Year 2012-2013). Post Graduate Medical Education (PGME), Department of Paediatrics, University of Toronto.

2011 The British Methodist Episcopal Church and Toronto Police Service Community Award.

Publications

Publications (Selected)

Journal Articles
1. Hugle B, Silverman ED, Tyrrell PN, Harvey EA, Hebert D, Benseler SM.  Presentation and Outcome of Paediatric Membranous Non-Proliferative Lupus Nephritis. Pediatric Nephrology, 2015: Jan; 30(1): 113-21.

2. Vali R, Ranson M, Harvey EA, Shammas A. False-positive in 111-DTPA Octreotide Scintigraphy in Bilateral Tibial Insufficiency Fracture.  Paediatric Radiology, 2014: Jun.  DOI 10.1007/s00247-014-3029-6 .  [Epub ahead of print].

3. Moalem S, Brouillard P, Kuypers D, Legius E, Harvey E, Taylor G, Francois M, Vikkula M, Chitayat D. Hypotrichosis-Lymphedema-Telangiectasia-Renal defect Associated with a Truncating Mutation in the SOX18 Gene. Clinical Genetics, 2014: Apr. DOI: 10.1111/cge.12388 [Epub ahead of print].

4. Rudzinski JK, Weber B, Wildgoose P, Lorenzo A, Bagli D, Farhat W, Harvey EA, Salle JL. Does routine ultrasound change management in the follow-up of patients with vesicoureteral reflux? Canadian Urological Association Journal, 2013 Jul-Aug;7(7-8): E467-9. DOI: 10.5489/cuaj.202. Erratum in: Canadian Urological Association Journal, 2013 Jul;7(7):223.

5. Hothi DK, Stronach L, Harvey EA. Home haemodialysis. Pediatric Nephrology 2013: May; 28(5):721-30.

6. Noone D, Al-Matrafi J, Tinckam K, Zipfel PF, Herzenberg AM, Thorner PS, Kahr WHA, Filler G, Hebert D, Harvey EA, Licht C.  Antibody Mediated Rejection Associated with Complement Factor H Related Protein 3/1 Deficiency Successfully Treated with Eculizumab.  Am. J. Transplant., 2012: Sep; 12(9): 2546-2553.

7. Lim SHL, Benseler S, Tyrrell P, Harvey EA, Herbert D, Charron M, Silverman E.  Predicting longitudinal trajectory of bone mineral density in paediatric systemic lupus erythematosus patients.  Annals of the Rheumatic Diseases, 2012: Mar; 71(10): 1686-1691.

8. Lim SHL, Benseler S, Tyrrell P, Charron M, Harvey EA, Hebert D, Silverman E.  Low Bone Mineral Density is Present in Newly Diagnosed Pediatric Systemic Lupus Erythematosus (pSLE) Patients. Annals of the Rheumatic Diseases, 2011: 70(11): pp 1991-4.

9. Al Kalbani N, Frieling M, Teh JC, Harvey EA, Geary D. Idiopathic hypercalcemia in infants with renal dysplasia. Clinical Nephrology, 2011: May; 75(5): 466-71.

10. Koltin D, Rachmiel M, Wong BY, Cole DE, Harvey EA, Sochette E. Mild Infantile Hypercalcemia – Diagnostic Tests and Outcomes. The Journal of Paediatrics, 2011: August; 159(2): 215-221.e1.Epub 2011 Mar 1