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About Sickkids
About SickKids

Edgar Jaeggi, MD, FRCPC

The Hospital for Sick Children
Staff Cardiologist
Cardiology

Head, Fetal Cardiac Program
Fetal Cardiac Program

Research Institute
Senior Associate Scientist
Translational Medicine

University of Toronto
Professor
Department of Paediatrics


Phone: 416-813-7466
Fax: 416-813-7547
Email: edgar.jaeggi@sickkids.ca
Alternate Contact: Gabriela Salle
Alternate Phone: 416-813-7654 x 203522
Alternate Email: gabriella.salle@sickkids.ca

Brief Biography

Dr. Edgar Jaeggi graduated from the Medical School at the University of Basel, Switzerland, in 1984. Following his paediatric residency in Switzerland, Jaeggi trained in paediatric cardiology at the University Children's Hospitals of Zurich and Geneva, Switzerland, the Westmead Hospital in Sydney, Australia, in fetal and interventional cardiology at the Sainte-Justine Hospital in Montreal and electrophysiology at The Hospital for Sick Children (SickKids) in Toronto.

In 1998, Jaeggi joined the clinical staff at the University Hospital of Geneva where he directed the Pediatric Electrophysiology Service. In September 2002, he returned to Toronto to join the Division of Cardiology and the Translational Medicine program at SickKids. In December 2003, Jaeggi became the head of the Fetal Cardiac Program, one of the largest and most successful fetal cardiac programs world-wide.

Clinical Care Activities

  • Fetal and paediatric echocardiography
  • In-patient/out-patient care

Research Interests

  • Rhythm and conduction anomalies with a special interest in congenital heart block
  • Prenatal programming of cardiovascular disease
  • Prenatal therapy and interventions
  • New imaging tools
  • Arrhythmia: special research interests are the diagnosis, management and outcome of fetal brady- and tachyarrhythmia. This work aims at tailoring a rationale treatment schedule for the fetus and mother
  • Intrauterine Growth Restriction:  Fetal growth restriction will occur in about 10 per cent of all pregnancies, and is a leading cause of mortality and disability. The aim of my research is to understand the prenatal hemodynamic mechanisms that lead to abnormal brain and vascular function and to use the information to develop new therapeutic strategies or to improve existing therapies.

Publications

Nii M, Hamilton RM, Fenwick L, Kingdom J, Roman KS, Jaeggi ET. Assessment of fetal atrioventricular time intervals by tissue Doppler and pulse Doppler echocardiography: Normal values and correlation with fetal electrocardiography. Heart 2006;92;1831-1837  

Roman KS, Fouron JC, Nii M, Smallhorn JF, Chaturvedi R, Jaeggi ET. Determinants of outcome of fetal pulmonary stenosis or atresia and intact ventricular septum. Am J Cardiol 2007;99:699-703   

Schmidt M, Jaeggi E, Ryan G, Hyldebrandt J, Lilly J, Benson L, Peirone A, Hjortdal V, Chaturvedi R. Stenting of the atrial septum in fetal lambs. Ultrasound Obstet Gynecol 2008;32:923-928   

Jaeggi ET, Laskin CA, Hamilton RM, Kingdom J, Silverman ED. The importance of maternal anti-Ro/SSA antibodies as prognostic markers of the development of cardiac neonatal lupus erythematosus: a prospective study of 186 antibody-exposed fetuses and infants. J Am Coll Cardiol 2010:55:2778-84  

Sarkola T, Redington A, Keeley F, Bradley T, Jaeggi E. Transcutaneous very high resolution to quantify arterial wall layers in muscular and elastic arteries: Validation of a novel imaging modality.  Atherosclerosis 2010;212:516-23  

Trucco SM, Jaeggi E, Cuneo B, Moon-Grady AJ, Silverman E, Silverman N, Hornberger LK. Use of intravenous gammaglobulin and corticosteroids in the treatment of maternal autoantibody mediated cardiomyopathy. J Am Coll Cardiol 2011;57:715-23  

Jaeggi E, Silverman ED, Laskin CA, Kingdom J, Golding F, Weber R. Prolongation of the atrio-ventricular conduction in fetuses exposed to maternal anti-Ro/SSA and anti-La/SSB antibodies does not predict progressive heart block. J Am Coll Cardiol: 2011:57:1487-92

Sarkola T, Redington A, Slorach C, Hui W, Bradley T, Jaeggi E. Assessment of vascular phenotype using a novel very-high-resolution ultrasound technique in adolescents after aortic coarctation repair and/or stent implantation: relationship to central haemodynamics and left ventricular mass. Heart 2011; in Press

Jaeggi E, Carvalho JS, De Groot E, Api O, Clur SA, Rammeloo L, McCrindle BW, Ryan G, Manlhiot C, Blom NA. Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide and sotalol: Results of a non-randomized multicenter study. Circulation 2011; in Press