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About Sickkids
About SickKids

Shaf Keshavjee, MD, MSc, FRCSC, FACS

The Hospital for Sick Children
Head, Lung Transplant Program
Transplant Centre

University of Toronto
Toronto Lung Transplant Program

Other Positions

Toronto General Research Institute
Division of Experimental Therapeutics
Senior Scientist, Director, Latner Thoracic Research Laboratories

Phone: 416-340-4010
Fax: 416-340-4556
Email: shaf.keshavjee@uhn.on.ca

Brief Biography

Shaf Keshavjee is the Surgeon-in-Chief at University Health Network. He is the Director of the Toronto Lung Transplant Program - a University program spanning UHN and the Hospital for Sick Children. He is a Professor in the Division of Thoracic Surgery at the University of Toronto. He is also Head of the Joint Division of Thoracic Surgery of UHN and St Joseph’s Hospital, McMaster University.

Dr Keshavjee completed his medical training at the University of Toronto in 1985. He subsequently trained in General Surgery, Cardiac Surgery and Thoracic Surgery at the University of Toronto followed by fellowship training at Harvard University and the University of London for airway surgery and heart-lung transplantation respectively. He joined the faculty at the University of Toronto in 1994.

Dr Keshavjee’s clinical practice in Thoracic Surgery is based at TGH, he also leads a team of researchers in a well-established CIHR funded research program and is widely published in the field. His specific research interest is in lung injury related to transplantation. His current work involves the study of molecular diagnostics and gene therapeutic strategies to engineer better organs for lung transplantation.

Research Interests

Lung injury related to lung transplantation, molecular diagnostics for transplantation, Gene Therapy in Lung Transplantation


  • Anraku M, Cameron MJ, Waddell TK, Liu M, Arenovich T, Sato M, Cypel M, Pierre AF, de Perrot M, Kelvin DJ, Keshavjee S. Impact of human donor lung gene expression profiles on survival after Lung Transplantation: A Case-Control Study. Am J Transplant 2008, 8: 2140-8.
  • Sato M, Keshavjee S. Bronchiolitis obliterans syndrome: alloimmune-dependent and independent injury with aberrant tissue remodeling. Semin Thorac Cardiovasc Surg 2008, 20: 173-182.
  • Cypel M, Yeung JC, Hirayama S, Rubacha M, Fischer S, Anraku M, Sato M, Harwood S, Pierre A, Waddell TK, de Perrot M, Liu N, Keshavjee S. Technique for prolonged normothermic ex vivo lung perfusion. J Heart Lung Transplant. 2008, 27:1319-25.
  • Christie J, Keshavjee S, Orens J, Arcasoy S, De Perrot M, Barr M, Van Raemdonock D; ISHLT Working Group on PGD. Potential refinements of the International Society for Heart and Lung Transplantation primary graft dysfunction grading system. J Heart Lung Transplant. 2008, 27:138.
  • Boasquevisque CH, Yildirim E, Waddell TK, Keshavjee S. Surgical techniques: lung transplant and lung volume reduction. Proc Am Thora Soc. 2009, 6: 66-78.
  • Ng YL, Paul N, Patsios D, Walsham A, Chung TB, Keshavjee S, Weisbrod G. Imaging of lung transplantation: review. AJR Am J Roentgenol. 2009, 192: S1-13.