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About Sickkids
About SickKids

Nicole Law

Research Institute
Doctoral student
Neurosciences & Mental Health

Phone: 416.813.7654 ext. 301741
Email: nicole.law@sickkids.ca

Brief Biography

Nicole is a Doctoral student in the Program in Neuroscience and Mental Health at The Hospital for Sick Children (SickKids). She is currently completing her PhD dissertation in the Department of Psychology (Clinical Extension Program) and in the Collaborative Program in Neuroscience (CPIN) at the University of Toronto. Her general research interests involve investigating brain-behaviour relations: specifically, elucidating the neural mechanisms underlying cognitive processes (e.g. executive function, working memory) in the healthy and injured developing brain. Nicole uses diffusion tensor imaging (DTI) to map white matter connections and examine white matter microstructure in the developing brain. Her Doctoral research involves investigating associations between brain structure and function in children with brain tumors, a population commonly treated with surgery and cranial radiation and often presents with neurotoxicity and cognitive morbidity following treatment. Further, she uses DTI to examine the relations between regional white matter microstructure and connectivity and neuropsychological outcome in the healthy and radiated brain. She is also interested in investigating clinical and neuroanatomical predictors of Cerebellar Mutism Syndrome, a post-surgical complication that occurs in up to 25% of children treated for brain tumors arising in the posterior fossa.

Nicole collaborates with several other laboratories at SickKids. She provides neuropsychological research assessment for several ongoing pediatric epilepsy studies; one using DTI for the assessment of white matter injury in children with non-lesional intractable focal epilepsy, and another examining quantitative neuroimaging markers of executive dysfunction in children with frontal lobe epilepsy. She has also collaborated on a study investigating cerebellar parcellations (e.g. volumetrics) and working memory and attentional functioning in spina bifida myelomeningocele. Nicole is affiliated with the Pediatric Oncology Group of Ontario (POGO) and was a research fellow within the POGO Research Unit (PRU) from 2010-2013. Nicole’s work is funded by the PRU, Genome Canada, Canadian Cancer Society, and C17 Children’s Cancer and Blood Disorders Research Grant.