About Sickkids
About SickKids

Brian McCrindle, MD, MPH, FRCP(C), FACC

The Hospital for Sick Children
Staff Cardiologist & Section Head of Epidemiology
Cardiology

Research Institute
Senior Scientist
Child Health Evaluative Sciences

University of Toronto
Professor
Paediatrics

Other Positions

CIBC World Markets Children’s Miracle Foundation
CIBC and Youth
Chair in Child Health Research


Phone: 416-813-7610
e-mail: brian.mccrindle@sickkids.ca

Brief Biography

Education

  • 1976-82 (Medicine)
    University of Alberta, Edmonton, AB, BMedSc, MD
  • 1983-90 (Pediatrics, Cardiology, Public Health)
    Johns Hopkins University, Baltimore, MD, FRCPC, MPH

Previous positions

  • 1990-1992
    Assistant Professor, Pediatrics & Community Health, University of Manitoba, Winnipeg, MB
    Staff Cardiologist, Variety Children's Heart Centre
  • 1992-1995
    Assistant Professor, Paediatrics, University of Toronto
    Staff Cardiologist, The Hospital for Sick Children
  • 1995-2002
    Associate Professor, Paediatrics, University of Toronto
    Staff Cardiologist, The Hospital for Sick Children
  • 2002-Present
    Professor, Paediatrics, University of Toronto
    Staff Cardiologist, The Hospital for Sick Children
  • 2003-present
    CIBC World Markets Children's Miracle Foundation
    Endowed Chair in Child Health Research

Current positions

  • Director - Cardiac Data Centre, Paediatric Lipid Disorders Clinic, Cardiovascular Clinical Research Unit - The Hospital for Sick Children
  • Core Faculty & Executive Committee Member - Clinical Epidemiology, Department of Health Policy, Management and Evaluation - University of Toronto
  • Co-director - Congenital Heart Surgeons Society Data Center
  • Chair - Committee on Atherosclerosis, Hypertension and Obesity in the Young, Council on Cardiovascular Disease in the Young - American Heart Association
  • Co-chair - Alliance for a Healthier Generation, Health Care Markets Pillar - American Heart Association and the Clinton Foundation

Research Interests

  1. Clinical aspects of lipid disorders and cardiovascular risk factors assessment and intervention, clinical trials.
  2. Cardiologic aspects of Kawasaki disease, particularly assessment and intervention for cardiovascular risk.
  3. An evidence-based approach to common paediatric cardiovascular disorders and complaints.
  4. Psychosocial, neurodevelopmental and quality of life aspects relevant to paediatric cardiology.
  5. Outcomes assessment of congenital heart disease and interventions, both in children and adults.

Research Activities

Member, Expert Panel
Pediatric Cardiovascular Risk Reduction Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, Science Committee and Lipid Subcommittee member, 2006 to present;

Theme Working Group Member
Canadian Heart Health Strategy-Action Plan, Federal Ministry of Health in conjunction with the Heart and Stroke Foundation of Canada and the Canadian Cardiovascular Society, 2007;

Member and presenter
Working Group on Future Research Directions in Childhood Obesity Prevention and Treatment, sponsored by the National Heart, Lung and Blood Institute, NIH, August 21-22, 2007; Co-Chair,

Organizer, Moderator and Speaker
Childhood Obesity Research Summit, American Heart Association Council on Cardiovascular Disease in the Young, Arlington, VA, December 6-8, 2007

Publications

Newburger JW, Sleeper LA, McCrindle BW, Minich LL, Gersony W, Vetter VL, Atz AM, Li JS, Takahashi M, Baker AL, Colan SD, Mitchell PD, Klein GL, Sundel RP for the Pediatric Heart Network Investigators: Randomized trial of pulse steroid therapy for primary treatment of Kawasaki disease. New Engl J Med 2007 February 15; 356(7):663-675

McCrindle BW, Li JS, Minich LL, Colan SD, Atz AM, Takahashi M, Vetter VL, Gersony WM, Mitchell PD, Newburger JW, for the Pediatric Heart Network Investigators: Coronary artery involvement in children with Kawasaki disease: risk factors from analysis of serial normalized measurements. Circulation 2007 July 10;116(2):174-179

McCrindle BW, Williams RV, Mitchell PD, Hsu DT, Paridon SM, Atz AM, Li JS, Newburger JW, for the Pediatric Heart Network Investigators: The relationship of patient and medical characteristics to health status in children and adolescents after the Fontan procedure. Circulation 2006 February; 28(113):1123-1129

Yetman AT, McCrindle BW, MacDonald C, Freedom RM, Gow RM: Myocardial bridging in children with hypertrophic cardiomyopathy-a risk factor for sudden death. New Engl J Med 1998; 339:1201-1209. (Co-principal author) R Comment in: NEJM 1999; 341(4):288-290

Schindler MB, Cox PN, Bohn D, McCrindle BW, Jarvis A, Barker G, Edmonds J: Factors influencing outcome from out-of-hospital paediatric cardiopulmonary arrest. New Engl J Med 1996; 335:1473-1479