Brief Biography

Dr. Daune MacGregor is a Paediatric Neurologist at The Hospital for Sick Children, Toronto, Canada. She completed her medical training at the University of Saskatchewan graduating cum laude in 1971. She then trained in Paediatrics and Neurology in Toronto at the Hospital for Sick Children and did postgraduate studies in Developmental Neurology at The Hospital for Sick Children Great Ormond Street, London, England and the Children’s Hospital Medical Center at Harvard University in Boston, Massachusetts. She is currently a staff neurologist and Associate Chair, Clinical Services, and Associate Paediatrician-in-Chief in the Department of Paediatrics at The Hospital for Sick Children. She was appointed a Full Professor of Paediatrics and Neurology at the University of Toronto in 1995.

Her current research interests are in the study of cerebral vascular disorders including stroke and headache, neurodevelopmental disorders including spina bifida and acquired brain injury in children. Dr. MacGregor is the current President of the Canadian Association of Child Neurologists.

Areas of Specialty:

Cerebrovascular disorders, headache, head\ache, developmental disabilities.

Academic Background

MD
University of Saskatchewan

Clinical Fellowship, Developmental Paediatrics and Mental Retardation
Children’s Hospital Medical Center, Harvard Medical School and Great Ormand Stre

Research Interests

• Childhood stroke, cerebrovascular disorders, recovery following head injury.

Research Activities

• stroke prevention in sickle cell anemia
• Canadian Paediatric Ischemic Stroke Registry
• hydrocephalus: MRI morphometric & cognitive correlations.
• pharmacological treatment of migraine
• neurobehavioural outcome of head injury in children
• acute disseminated encephalomyelitis
• predictors of neurodevelopmental outcome after neonatal cardiopulmonary bypass

Achievements

1992 - Teacher of the Year Award - Division of Neurology, Hospital for Sick Children, University of Toronto

1998 - Fellow of the American Academy of Neurology

1998 - Teacher of the Year Award - Division of Neurology - Hospital for Sick Children, University of Toronto

1999 - Nominee - PAIRO Resident Advocate Award

2000 - Nominee - PAIRO Resident Advocate Award

Publications

deVeber GA, MacGregor D, Curtis R, Mayank S: Neurological outcome of survivors of childhood arterial ischemic stroke and sinovenous thrombosis. Journal of Child Neurology 2001: 15: pp 316-324.

Golomb M, MacGregor D, Domi T, Armstrong D, McCrindle B, Mayank S, deVeber G: Presumed pre-or perinatal arterial ischemic stroke: Risk factors and outcome. Annals of Neurology 2001: 50: pp 163-168.

deVeber G, MacGregor D, Curtis R, Mayank S: Neurological outcome in survivors of childhood arterial ischemic stroke and sinovenous thrombosis. Journal of Child Neurology 2001: 15: pp 316-324.

Friefeld Sharon, MacGregor Daune, Chuang Sylvester, Saint-Cyr, Jean: A Comparative study of inter-and intrahemispheric somatosensory functions in children with partial and complete agenesis of the corpus callosum. Developmental Medicine and Child Neurology 2001: 42: pp 831-838.

DeVeber G, Andrew M and Canadian Paediatric Ischemic Stroke Group (MacGregor DL): Cerebral sinovenous thrombosis in children. New England Journal of Medicine 2001: 345(6):417-23.

Shinar Y, Ben-Zeev B, Brand N, Lahat H, Gross-Zur V, MacGregor D, Bahan T, Kastner DL, Pras E: A common ancestral haplotype in carrier chromosomes from different ethnic backgrounds in vacuoliting megalencephalic leukoencephalopathy with subcortical cysts. Journal of Medical Genetics; 2002:39(1):54-57.