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About Sickkids
About SickKids

Todd Mainprize, MD

Research Institute
Principal Investigator
The Arthur and Sonia Labatt Brain Tumour Research Centre

Other Positions

Sunnybrook Hospital
Department of Neurosurgery

Phone: 416-480-4739
Email: todd.mainprize@sunnybrook.ca

Brief Biography

Dr. Todd Mainprize is a neurosurgeon who trained at the University of Toronto and who currently works at Sunnybrook Health Sciences Centre. He works with traumatic spinal injuries and degenerative spinal problems.

Research Interests

Mainprize has two main areas of research interest. He is collaborating with scientists at Sunnybrook Health Sciences Centre to investigate the utility of MR-guided focused ultrasound in the treatment of primary and metastatic brain tumours. This novel modality can be used to safely and reversibly disrupt the blood-brain barrier allowing for better delivery of chemotherapeutic agents to the tumour. Additionally, at higher energies, focused ultrasound can target and destroy the tumour cells with millimetre accuracy and may be a radiation-free alternative to radiosurgery.  

Secondly, Mainprize is investigating the various pathway dysregulations in meningiomas with the hope of developing more effective treatments for recurrent and higher grade tumours.


A list of Dr. Mainprize's publications can be found on PubMed