Academic Background

Degrees, Diplomas, and Certification

1983-1985 University of Guelph, Guelph Ontario, Canada

1985-1989 Royal College of Surgeons Dublin, Ireland

1989-1991 Albany Medical College MD Albany, New York, USA

1997-1999 University of Michigan MS Ann Arbor, MI, USA Clinical Research Design and Biostatistics

Certification

1991    National Board Medical Examination

1995    American Board of Internal Medicine

1995    American Board of Pediatrics

1999    American Board of Pediatrics, Subspecialty Pediatric Nephrology;  Recertified 2006.

1999    American Board of Internal Medicine, Subspecialty Nephrology

CLINICAL TRAINING:

1991-1995 University of Michigan Combined Internal Medicine and Ann Arbor, MI, USA Pediatric Internship and Residency

1995-1999 University of Michigan Combined Medicine and Pediatric Ann Arbor, MI, USA Nephrology Fellowships

RESEARCH TRAINING:

1997-1999 University of Michigan Post Doctoral Research Fellow in Ann Arbor, MI, USA Nephrology

1999 Johns Hopkins University Post Doctoral Research Fellow in Baltimore, MD, USA Pediatric Nephrology

External Funding

Last 5 Years

2000-2005 NIH-NIDDK Diabetic and Nondiabetic Nephropathy Susceptibility Genes 1UO1-DK-57304-01 (Klag) Co-investigator Clinical Quality Control Sub-Committee

2001-2005 NIH-NIDDK Mentored Patient-Oriented Research Career Development Award ‘A prospective study of young adults with ESRD’ Principal Investigator 1K23DK02872-01A1 Project Period: 09/30/2001 - 08/31/2005 Total Direct Costs: $494,678

2004-2010 Merck Oxford Trials Group, Oxford, United Kingdom Study of Heart and Renal Protection (SHARP) Johns Hopkins University Local Lead Investigator Annual Direct Costs:  $25,920

2005-2008  Astra- Zeneca Adherence in Children with Hypertension Co-investigator Total Direct Costs: 100,000

2005-2009 NIH-NIDDK Identification of Genes for ESRD in African-Americans 1 R01 DK070657-01 (Kao) Co-investigator Annual Direct Costs: $374,669

2005-2010 Renal Disease Epidemiology Training Program 1 T32 DK07732 (Klag) Co-investigator/Associate Director Annual Direct Costs: $287,119

2005-2010 Program to Train Predoctoral Students in Clinical Research 1 T32 HD052253-01 (Powe) Co-investigator

2007-2008 NIH/NCRR Institute for Clinical and Translational Research UL1 RR025005 (Ford) Mentor Annual Direct Costs: $10,707,230

2005-2007 NIH/NIDDK Diabetic and Nondiabetic Nephropathy Susceptibility Genes 1UO1-DK-57304-01 continuation Principal Investigator Annual Direct Costs: $200,000

2007-2011 NIH/NIDDK Predictors and Consequences of Chronic Kidney Disease 1R01 DK076770-01 (Astor) Co-investigator Annual Direct Costs: $519,186   

2007-2012 NIH/NIDDK Environmental Exposure to Metal Mixtures and Kidney Disease R03 ES016433 (Fox) Collaborator Annual Direct Costs:  $49,000

2007-2012 NIH/NIDDK Longitudinal Study of Dialysis R01 DK72367-01A2 Principal Investigator Annual Direct Costs: $452,033

2007-2008 National Kidney Foundation of Maryland Mineralization and Cardiovascular Disease Risk in an Incident Dialysis Cohort Principal Investigator Total Direct Costs: $10,000  

2007-2009 National Kidney Foundation of Maryland Mini-Grant Vascular Calcification and  Calcification Risk Factors in an Incident Dialysis Cohort Total Direct Costs: $7826.87 (Sozio) Mentor

2009-2010 Abbott Mineralization Factors and Atherosclerotic Risks in Dialysis Johns Hopkins University Principal Investigator Total Direct Costs:  $222,381

2009-2010 Johns Hopkins Global Health Incidence And Determinants Of Post Myocardial Infarction Sudden Cardiac Death In South Indians Annual Direct Cost: $50,000.

Achievements

Selected

1987 Evatt Memorial Prize in Anatomy

1993 Bronze Beeper Award for recognition of medical student teaching

1994 Bronze Beeper Award for recognition of medical student teaching

1994 Bruce A Jones Award for Outstanding House Staff Spirit

1995 Second Place in Fellow Case Presentation at 6th NAPRTCS Workshop

1996 Blue Ribbon Abstract at American Society of Nephrology

1997-1999 American Kidney Fund Clinical Scientist in Nephrology Award

1999-2000 Renal Disease Epidemiology Training Grant Recipient

2000 American Society of Nephrology-Carl W. Gottschalk Research Scholar Grant

2003 Listed in “Guide to America’s Top Physicians”

2005-2008 Associate Director of the Renal Disease Epidemiology Training Grant

2007 The Advising, Teaching and Mentoring Award (AMTRA), Bloomberg School of Public Health.

Publications

Selected

Bash LD, Coresh J, Köttgen A, Parekh R, Fulop T, Wang Y, Astor BC.  Defining Chronic Kidney Disease in the Research Setting: The Atherosclerosis Risk in Communities (ARIC) Study.  American Journal of Epidemiology, Am J Epidemiol. 2009 Jun 17. [Epub ahead of print]. C  PMID: 19535543

Invited Commentary:  Stephen J. Tonna,  Defining Incident Chronic Kidney Disease in Epidemiologic Study Settings. Am. J. Epidemiol. 2009 170: 425-427.

ES Kraus, RS Parekh, P Oberai, D Lepley, DL Segev,  S Bagnasco, V Collins, M Leffell, D Lucas, H Rabb, LC Racusen,  AL Singer, ZA Stewart, DS Warren, AA Zachary, M Haas, and RA Montgomery.  High incidence of subclinical cellular and antibody mediated rejection detected during surveillance biopsies in stable ABO incompatible and positive crossmatch kidney transplant patients.  American Journal of Transplantation, Am J Transplant. 2009 Jun 16. [Epub ahead of print]. CPA PMID: 19538492

Admixture mapping of 15, 280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X', Ching-Yu Cheng, W. H. Linda Kao, Nick Patterson, Arti Tandon, Christopher A.Haiman, Tamara B. Harris, Chao Xing, Esther M. John, Christine B. Ambrosone,Frederick L. Brancati1, Josef Coresh,  Michael F. Press, Rulan S. Parekh, Michael J.Klag, Lucy A. Meoni, Wen-Chi Hsueh, Laura Fejerman, Ludmila Pawlikowska, ,Matthew L. Freedman, Lina H. Jandorf, Elisa V. Bandera, Gregory L. Ciupak, Michael A. Nalls Ermeg L. Akylbekova, Eric S. Orwoll, Tennille S. Leak, Iva Miljkovic,Rongling Li, Giske Ursin, Leslie Bernstein, Kristin Ardlie Herman A. Taylor, Eric Boerwinckle, Joseph M. Zmuda, Brian E. Henderson, James G. Wilson, David Reich.  PLoS Genetics, PLoS Genet. 2009 May;5(5):e1000490. Epub 2009 May 22. C PMID: 19461885

Peripheral Vascular Disease-related Procedures in Dialysis Patients: Predictors and Prognosis Laura C. Plantinga, Nancy E. Fink, Josef Coresh, Stephen M. Sozio, Rulan S. Parekh, Michal L. Melamed, Neil R. Powe, and Bernard G. Jaar, Clin J Am Soc Nephrol. 2009 Oct;4(10):1637-45. Epub 2009 Aug 13. C

Chu AY, Parekh RS, Astor BC, Coresh J, Berthier-Schaad Y, Smith MW, Shuldiner AR, Kao WH. Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study. BMC Med Genet. 2009 Oct 23;10:108. C

Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group. Malhotra A, Igo RP Jr, Thameem F, Kao WH, Abboud HE, Adler SG, Arar NH, Bowden DW, Duggirala R, Freedman BI, Goddard KA, Ipp E, Iyengar SK, Kimmel PL, Knowler WC, Kohn O, Leehey D, Meoni LA, Nelson RG, Nicholas SB, Parekh RS, Rich SS, Chen YD, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Taylor KD, Thornley-Brown D, Zager PG, Horvath A, Hanson RL; Family Investigation of Nephropathy and Diabetes Research Group. Diabetes Metab Res Rev. 2009 Nov;25(8):740-7.PMID: 19795399 C

Predictors and Consequences of Higher Estimated Glomerular Filtration Rate at Dialysis Initiation in Children. Meredith A. Atkinson, Alicia M. Neu, Pooja Oberai, M.S., Barbara A. Fivush, and Rulan S. Parekh.  Pediatr Nephrol. 2010 Feb 27. [Epub ahead of print] PMID: 20191370 SRI

Prevalence of kidney disease in anemia differs by GFR-estimating method: The Third National Health and Nutrition Examination Survey (1988-1994). Michelle M. Estrella, Brad C. Astor, PhD, Anna Köttgen, Elizabeth Selvin, Josef Coresh and Rulan S. Parekh. Nephrol Dial Transplant. 2010 Feb 22. [Epub ahead of print] PMID: 20176612 SRI

Patient, Provider and Clinic Level Predictors of Unrecognized Elevated Blood Pressure in Children. Tammy M. Brady, Barry S. Solomon, Alicia M. Neu, George K. Siberry, Rulan S. Parekh, Pediatrics published online: doi: 10.1542/peds.2008-1536. SRI

Residual Urine Output Is Associated with Mortality, Quality of Life and Inflammation in Incident Dialysis Patients: The CHOICE Study. Tariq Shafi, Bernard G. Jaar, Laura C. Plantinga, Nancy E. Fink, John H. Sadler, Rulan S. Parekh, Neil R. Powe, Joseph, Coresh.  American Journal of Kidney Disease, in press. C

Michelle M. Estrella, Rulan S. Parekh, Alison Abraham, Brad C.  Astor, Lynda A. Szczech, Kathryn Anastos, Jack A. Dehovitz, Daniel J. Merenstein, C. Leigh Pearce, Phyllis C. Tien,  Mardge H. Cohen, and Stephen J. Gange. The impact of kidney function at HAART initiation on mortality in HIV-infected women. JAIDS, in press. SRI