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About Sickkids
About SickKids

Julian Raiman

The Hospital for Sick Children
Staff Physician
Clinical and Metabolic Genetics

Research Institute
Project Investigator
Research Institute

University of Toronto
Assistant Professor
Pediatrics


Phone: 416 813-7654 Ext 201480
Fax: 416 813-5345
Email: julian.raiman@sickkids.ca

Brief Biography

Dr Raiman received his paediatric training through posts in a variety of London teaching and other hospitals within the UK South Thames region as well as a one yearneonatal fellowship in Sydney, Australia. His metabolic training was completed at The Hospital for Sick Children, Toronto as Departmental Fellow between 2002-2004; before being appointed as Consultant in Paediatric Metabolic Medicine at the Evelina Children’s Hospital, Guy’s and St Thomas’ Hospital, London,  UK in July 2004. He rejoined the Division of Clinical and Metabolic Genetics as an Academic Clinician in February 2007.
He is currently the lead clinician for the Lysosomal Storage Disease patients within the hospital, is a Project Investigator in the Research Institute collaborating on a variety of ongoing trials including being a site investigator for the NIH Lysosomal Diseases Network and a Phase 3 extension trial for ERT in MPSIVA. He sits on the Medical Advisory Boards of the Canadian Chapter of the National Niemann Pick Disease Foundation, The Canadian Society for MPS and Allied Diseases, The Isaac Foundation as well as the North American Board for the Hunter Outcome Survey.

Research Interests

  • Treatment of Lysosomal Storage Diseases

Selected Publications

COLL.  De Ru MH, Teunissen QG, van der Lee JH, Beck M, Bodamer OA, Clarke LA, Hollak CE, Lin SP, Munoz Rojas MV, Pastores GM, Raiman J, Scarpa M, Treacy EP, Tylki-Szymanska A, Wraith E, Zeman J, Wijburg FA:  Capturing phenotypic heterogeneity in MPS I – results of an international consensus procedure.  Orphanet Journal of Rare Diseases 2012:  23;7(1):22.

CoPA.  Gassas A, Raiman J, White L, Schechter T, Clarke J, Doyle J:  Long-term adaptive functioning
outcomes of children with inherited metabolic and genetic disease treated with hematopoietic stem cell
transplantation in a single large pediatric center: parents’ perspective.  Journal of Pediatric
Hematology/Oncology 2011:  33(3): pp 216-20.

COLL.  Clarke JT, Mahuran DJ, Sathe S, Kolodny EH, Rigat BA, Raiman J, Tropak MB:  An open-label
Phase1/11clinical trial of pyrimethamine for the treatment of patients affected with chronic GM2 gangliosidosis
(Tay-Sachs or Sandhoff variants). Molecular Genetics and Metabolism 2011: 102(1): pp 6-12.

COLL.  Cameron JM, Levandovskiy V, Mackay N, Ackerley C, Chitayat D, Raiman J, Halliday WH, Schulze A,
Robsinson BH: Complex V TMEM70 deficiency results in mitochondrial nucleoid disorganization.  
Mitochondrion 2011: 11(1):  pp191-9.

COLL.  McClelland V, Cullup T, Bodi I, Ruddy D, Buj-Bello A, Biancalana V, Boehm J, Bitoun M, Miller O, Jan
W, Menson E, Amaya L, Trounce J, Laporte J, Mohammed S, Sewry C, Raiman J, Jungbluth H:  Vici
syndrome associated with sensorineural hearing loss and evidence of neuromuscular involvement on muscle
biopsy.  American Journal of Medical Genetics 2010:  152A(3):741-7.

COLL.  Cameron JM, Maj M, Levandovskiy V, Barnett CP, Blaser S, MacKay N, Raiman J, Feigenbaum A,
Schulze A, Robinson BH:  Pyruvate dehydrogenase phosphatase 1 (PDP1) null mutation produces a lethal
infantile phenotype.  Human Genetics (Berlin) 2009:  125(3):  319-26.

COLL.  Cameron JM, Levandovskiy V, MacKay N, Utgikar R, Ackerley C, Chiasson D, Halliday W, Raiman J, Robinson BH: Identification of a novel mutation in GYS1(muscle-specific glycogen synthase) resulting in sudden cardiac death, that is diagnosable from skin fibroblasts.  Molecular Genetics and Metabolism 2009:  98(4):  378-82.

PA.  Raiman J, Clarke JTR:  Existing diagnostic dilemmas in Anderson-Fabry disease and advances toward
their solution. Current Medical Literature – Lysosomal Storage Diseases 2008:  8(2):  pp 41-46.

COLL.  Footitt EJ, Sinha MD, Raiman J, Dhawan A, Moganasundram S, Champion MP: Mitochondrial
disorders and general anesthesia:  A case series and review.  British Journal of Anesthesia 2008: 100(4): pp
436-41.

COLL.  Beauchamp NJ, Dalton A, Ramaswami U, Niinikoski H, Mention K, Kenny P, Kolho KL, Raiman J,
Walter J, Treacy E,Tanner S, Sharrard M: Glycogen storage disease type IX:  High variability in clinical
phenotype.  Molecular Genetics and Metabolism 2007: 92(1-2): pp 88-99.

Achievements

2012 Robert Salter, Humanitarian Award, SickKids Foundation, Toronto, Ontario, Canada.

2011 Planters Tapestry Award for Cultural Competence,  The New Immigrant Support Network, The Hospital for Sick Children, Toronto, Ontario, Canada.

2010 Toronto EMS Citizenship Awards, Emergency Medical Services, Toronto, Ontario, Canada.

2008 The 2008 Interprofessional Practice Award in Paediatric Hospice Palliative Care, The Hospital for Sick Children, Toronto, Ontario, Canada.