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About Sickkids
About SickKids

Gino R. Somers, MBBS, PhD, FRCPA

The Hospital for Sick Children
Division Head
Pathology

Staff Pathologist
Pathology

University of Toronto
Associate Professor
Department of Laboratory Medicine & Pathology


Phone: 416-813-5430
Fax: 416-813-5479
Email: gino.somers@sickkids.ca

Brief Biography

Dr. Gino Somers obtained his medical degree from Monash University (Melbourne, Australia) in 1991 and received his PhD from the University of Melbourne in 1999. He finished his anatomical pathology training with the Royal College of Pathologists of Australia in 2002. He then went on to complete an 18 month paediatric pathology fellowship at The Hospital for Sick Children (SickKids) in 2004 and became a staff pathologist in 2005. Dr. Somers is an associate professor in the Department of Laboratory Medicine and Pathology at the University of Toronto and a Project Investigator with the Research Institute at the Hospital for Sick Children.

Clinical Activities 

Dr. Somers’ clinical care activities are performed in the Department of Paediatric Laboratory Medicine where he is involved in the diagnostic pathology service. Dr. Somers’ areas of interest include paediatric tumours, gastrointestinal pathology and diagnostic molecular pathology.

Research Interests

Dr. Somers’ research is focused primarily on paediatric sarcomas, and his laboratory has identified several genes and gene pathways involved in the critical early steps of sarcomagenesis. More recently, his work has focused on bringing in new diagnostic modalities to molecular pathology, specifically for aiding in the diagnosis of sarcomas.

Dr. Somers is also involved in several collaborative projects, including biomarkers in paediatric rhabdomyosarcoma and, improving laboratory efficiency through Lean management principles.

External Funding

  • Canadian Institutes of Health Research
  • Brain Tumour Assistance and Information Network
  • University of Toronto Dean's Fund and McLaughlin Centre
  • Garron Family Cancer Centre

Achievements

  • Harry Neustein Award, Society for Pediatric Pathology
  • Gordon Vawter Award, Society for Pediatric Pathology
  • John Brenan Prize, Australian Society of Dermatopathology
  • Young Achiever Award, Royal College of Pathologists of Australasia

Publications

Hettmer S, Archer NM, Somers GR, Novokmet A, Wagers AJ, Diller L, Rodriguez-Galindo L, Teot L, Malkin D. Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers. Cancer 2014;120(7):1068-75.

Rabah-Hammad RM, Somers GR, Comstock JM, Buchino JJ, Timmons CF. Fellowship training in pediatric pathology: A guide for program directors. Pediatric and Developmental Pathology 2013:16:102-123.

Graham C, Chilton-MacNeill S, Zielenska M, Somers GR. The CIC-DUX4 fusion transcript is present in a subset of pediatric primitive round cell sarcomas. Human Pathology 2012;43(2):180-189.

Sadikovic B, Graham C, Ho M, Zielenska M, Somers GR. Immunohistochemical expression and cluster analysis of mesenchymal and neural stem cell-associated proteins in pediatric sarcomas. Pediatric and Developmental Pathology 2011;14:259-272.

Durbin A, Somers GR, Forrester M, Hannigan, G, Malkin D. Integrin-linked kinase has both oncogenic and tumor-suppressive activity in rhabdomyosarcoma subtypes with critical dependency on JNK-c-Jun signalling for its tumor suppressor activity. Journal of Clinical Investigation 2009;119 (6): 1558-70


A detailed list of Dr. Somers' publications is available on Pub Med.