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About Sickkids
About SickKids

Lillian Sung, MD, PhD, FRCPC

The Hospital for Sick Children
Paediatric Oncologist
Haematology/Oncology

Research Institute
Senior Scientist
Child Health Evaluative Sciences

University of Toronto
Professor
Department of Paediatrics and Institute of Health Policy Management and Evaluation

Other Positions

Children's Oncology Group
Cancer Control and Supportive Care
Immediate Past Chair

Children's Oncology Group
Cancer Care Delivery Research
Chair

Canada (CYP-C) Management Committee
Cancer in Young People
Chair


Phone: 416-813-1500
Fax: 416-813-5327
Email: lillian.sung@sickkids.ca

Brief Biography

Dr. Sung joined the staff at The Hospital for Sick Children in September 2004 after completing fellowships in Haematology, Infectious Diseases and Clinical Investigation and receiving a PhD in Clinical Epidemiology from the University of Toronto.

She is a Paediatric Oncologist and Clinician Scientist with an independent research program focused on supportive care for children with cancer. Her overall goal is to optimize supportive care for children with cancer, with an aim to maximize quality of life, survival and cost-effectiveness. She is the Chair of Cancer Control and Supportive Care for the Children’s Oncology Group (COG). This group oversees all studies of supportive care including studies related to symptom management and patient-reported outcomes.

Her research program is currently focused on symptom screening and interventions to reduce fatigue in paediatric cancer patients. She holds a Canadian Cancer Society Research Institute Impact Grant and has previously received operating grants from the Canadian Institutes of Health Research and the National Institutes of Health (NIH, R21). She is the Co-Principal Investigator of the COG National Cancer Institute Community Oncology Research Program (UG1CA189955) and an NIH R25 in collaboration with the American Society of Hematology.

Her clinical focus is on the inpatient care of children and adolescents with leukemia and lymphoma. She also has a major focus on research education. She has taught graduate courses for the School of Graduate Studies, University of Toronto since her faculty appointment and she currently co-directs an advanced randomized trials course. In addition, she has contributed to the development of the Clinical Research Training Institute supported by the American Society of Hematology and developed a research training course in Latin America and Qatar.

Clinical Interests:

  • Inpatient care of children with leukemia and lymphoma.

Research Interests

  • Paediatric cancer supportive care
  • Measurement of symptoms – development of the Symptom Screening in Pediatrics Tool (SSPedi) and the Children’s International Mucositis Evaluation Scale (ChIMES)
  • Development of a website to promote symptom screening and access to clinical practice guidelines called Supportive care Prioritization: Assessment and Recommendations for Kids (SPARK)
  • Interventions to reduce symptoms including yoga to reduce fatigue
  • Optimizing management of fever and neutropenia
  • Clinical practice guideline development
  • Methodological foci: randomized trials, observational studies, meta-analysis, clinical practice guideline development, patient-reported outcomes, instrument development and instrument psychometric evaluation

External Funding

  • Canadian Institutes of Health Research
  • National Institutes of Health
  • Canadian Cancer Society Research Institute
  • Ontario Ministry of Research and Innovation
  • C17 Research Network
  • Pediatric Oncology Group of Ontario
  • Garron Family Comprehensive Cancer Centre
  • Rally Foundation

Achievements

  • 2016 - The Wendy Lack Memorial Scientific Achievement Award – The Israel Cancer Research Fund (ICRF)
  • 2015 and 2010 – POWER Teaching Award, Department of Paediatrics, The Hospital for Sick Children
  • 2014 – Canadian Cancer Society Research Institute Impact Grant “Development and validation of a pediatric cancer-specific symptom assessment screening tool”
  • 2011 - Frank Oski Lectureship - for outstanding clinical or laboratory investigator in paediatric hematology/oncology, American Society of Pediatric Hematology/Oncology
  • 2009-2014 - New Investigator Award, Canadian Institutes of Health Research
  • 2009 - Canadian Cancer Society Award for Excellence in Cancer Research – William E. Rawls Award in Cancer Control
  • 2008 – Junior Researcher Award – Research Institute, The Hospital for Sick Children
  • 2006 - Early Researcher Award – Ministry of Research and Innovation, Canada  
  • 2004 – Andrew Sass-Korsak Clinician Scientist Award – The Hospital for Sick Children

Publications

  1. Alexander S, Fisher BT, Gaur AH, Dvorak CC, Villaluna D, Dang H, Chen L, Green M, Nieder ML, Fisher B, Bailey LC, Wiernikowski, Sung L: Effect of levofloxacin prophylaxis on bacteremia in children with acute leukemia or undergoing hematopoietic stem cell transplantation: a randomized clinical trial. Journal of the American Medical Association in press. SRI
  2. Diorio C, Robinson PD, Ammann RA, Castagnola E, Erickson K, Esbenshade A, Fisher BT, Haeusler GM, Kuczynski S, Lehrnbecher T, Phillips R, Cabral S, Dupuis LL, Sung L: Guideline for the management of Clostridium difficile infection in children and adolescents with cancer and pediatric hematopoietic stem cell transplantation recipients. Journal of Clinical Oncology in press. SRI
  3. Alexander S, Pole JD, Gibson P, Lee M, Hesser T, Chi S, Dvorak CC, Fisher B, Hasle H, Kanerva J, Möricke A, Phillips B, Raetz E, Rodriguez-Galindo C, Samarasinghe S, Schmiegelow K, Tissing W, Lehrnbecher T, Sung L: Classification of treatment-related mortality in children with cancer: a systematic assessment. Lancet Oncology 2015:16(16):e604-10. SRI
  4. Robinson PD, Lehrnbecher T, Phillips B, Dupuis LL, Sung L: Strategies for empiric management of pediatric fever and neutropenia in cancer and hematopoietic stem cell transplantation recipients: a systematic review of randomized trials. Journal of Clinical Oncology 2016:34(17):2054-60. SRI
  5. Lehrnbecher T, Robinson P, Fisher B, Alexander Sarah. Ammann RA, Beauchemin, Carlesse F, Groll AH, Haeusler GM, Santolaya Maria, Steinbach William J, Castagnola E, Davis BL, Dupuis LL, Gaur AH, Tissing W, Zaoutis T, Philips R, Sung L: Guideline for the management of fever and neutropenia in children with cancer and hematopoietic stem cell transplantation recipients: 2017 update. Journal of Clinical Oncology 2017:20:35(18):2082-2094. SRI
  6. Freyer DR, Chen L, Krailo MD, Knight K, Villaluna D, Bliss B, Pollock BH, Ramdas J, Lange B, Van Hoff D, VanSoelen ML, Wiernikowski J, Neuwelt EA, Sung L: Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial. Lancet Oncology 2017:18(1):63-74. SRI
  7. Knight KR, Chen L, Freyer D, Aplenc R, Bancroft M, Bliss B, Dang H, Gillmeister B, Hendershot E, Kraemer DF, Lindenfeld L, Meza J, Neuwelt EA, Pollock BH, Sung L: Group-Wide, Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy (ACCL05C1): A Report From the Children's Oncology Group. Journal of Clinical Oncology 2017:35(4):440-445. SRI
  8. Kirch R, Reaman G, Feudtner C, Wiener L, Schwartz LA, Sung L, Wolfe J: Advancing a comprehensive cancer care agenda for children and their families: Institute of Medicine. CA: A Cancer Journal for Clinicians 2016:66(5):398-407. C
  9. Dupuis L, Johnston D, Baggott C, Hyslop S, Tomlinson D, Gibson P, Orsey A, Dix D, Price V, Vanan M, Portwine C, Kuczynski S, Spiegler B, Tomlinson G, Sung L: Validation of the Symptom Screening in Pediatrics Tool in children receiving cancer treatments. Journal of the National Cancer Institute 2018:110:661-68. SRI
  10. Treister N, Nieder M, Baggott C, Olson E, Chen L, Dang H, Krailo M, August A, Sung L: Caphosol for prevention of oral mucositis in pediatric myeloablative haematopoietic cell transplantation. British Journal of Cancer 2017:116(1):21-27. SRI
  11. King AA, Vesely SK, Elwood J, Basso J, Carson K, Sung L: The American Society of Hematology Clinical Research Training Institute is associated with high retention in academic hematology. Blood 2016:128(25):2881-2885. SRI

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