About Sickkids
About SickKids
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Stanley Zlotkin , OC, MD, PhD, FRCP(C)

The Hospital for Sick Children
Chief
Centre for Global Child Health

Research Institute
Senior Scientist
Child Health Evaluative Sciences

University of Toronto
Professor
Nutritional Sciences & Paediatrics


Phone: 416-813-8056
Fax: 416-813-5393
e-mail: stanley.zlotkin@sickkids.ca
Alternate Contact: Robyn Nicholson
Alternate Phone: 416-813-8056
Alternate Fax: 416-813-5393
Alternate e-mail: robyn.nicholson@sickkids.ca

Brief Biography

Stanley Zlotkin received his medical training at McMaster University in Hamilton, Ontario, paediatric training at McGill University in Montreal, and he obtained a PhD in nutritional sciences at the University of Toronto. He has worked as a clinician-nutritionist and research scientist at The Hospital for Sick Children since 1980. He is Professor in the Department of Paediatrics, the Dalla Lana School of Public Health and the Department of Nutritional Sciences at the University of Toronto, and past Head of the Division of Gastroenterology, Hepatology & Nutrition and Medical Director of Nutrition Support for SickKids.

In his program, the Sprinkles Global Health Initiative, Dr. Zlotkin has focused on research and advocacy to control micronutrient malnutrition in children. It is estimated that as many as 750 million children in developing countries suffer from micronutrient malnutrition. Challenged by UNICEF to come up with a viable and reproducible solution to the problem of micronutrient malnutrition, Dr. Zlotkin and his research team developed the concept of micronutrient powders for “home-fortification” of complementary foods. With support from USAID, Canadian Institutes of Health Research (CIHR) and private foundations, he has completed multi-country research in to prove the benefits of home-fortification to control micronutrient deficiencies. His current research focuses on delivery science to enhance the implementation of public health programs and products.

Dr. Zlotkin is past Chair of the Canadian Paediatric Society Nutrition Committee and is a frequent consultant to governments and UN agencies on issues related to global child health nutrition. His advocacy work was recognized by CIHR in 2006 with award of the prestigious CIHR National Knowledge Translation Award for “outstanding contributions to the health of children worldwide.” He was awarded the HJ Heinz Humanitarian Award in 2001 for his international contribution to the health of children globally. In 2007, he was awarded the Order of Canada, the highest civilian honour in Canada, for his contributions to improving the lives of children globally. He is known internationally as a successful social entrepreneur for his work on home fortification and was awarded an International Ashoka Fellowship in 2007. Today, Dr. Zlotkin continues to head the Sprinkles Global Health Initiative at The Hospital for Sick Children and is an active researcher with well over 100 peer-reviewed publications. Dr. Zlotkin was appointed as Vice-President Medical and Academic Affairs at SickKids in 2010 and in September 2012 he was named as the inaugural Chief of the SickKids Centre for Global Child Health.  

Research Interests

His research interests involve:
(i) examining mineral requirements and metabolism in premature and full-term infants, especially iron,
(ii) clinical trials to treat and prevent iron and vitamin A deficiency, and
(iii) establishing evidence-based nutrition public policy.

He has active research in Canada (supported by Health Canada and the CDC), Ghana (supported by the CIHR), Mongolia (supported by World Vision and the HJ Heinz Foundation) and India (supported by the CIHR).

Research Activities 

Fortification of infant food with iron to prevent iron-deficiency anaemia. Iron-deficiency anaemia is the most prevalent nutrient deficiency in the world today, affecting as many as 1.5 billion people. Groups at risk include women of child-bearing age, pregnant women, and rapidly growing infants, children, and adolescents. Infants with iron-deficiency anaemia may have nonreversible developmental delay. Using a food-fortification approach, my colleagues and I have initiated international collaborations to examine:

  1. the effect of a double-fortified table salt (fortified with dextran-coated iodine and iron) and
  2. microencapsulated ferrous fumarate sprinkles for weaning foods to prevent iron-deficiency anaemia in infants and young children.

Other research activities include investigations of iron bioavailability using stable isotope technology.

Achievements

2014 -  recipient of The Mathile Institute Award for Career Achievement in Evidence Translation.

2009 - recipient of the American Academy of Pediatrics (AAP) Samuel J. Fomon Nutrition Award.

2007 - awarded the Order of Canada.

2001 - recipient of the HJ Heinz Humanitarian Award. 

Publications

Dubyk MD, Card RT, Whiting SJ, Boyle CAJ, ZLOTKIN SH, Paterson PH.  Iron deficiency anemia prevalence at first stroke or transient ischemic attack. Can Journal of Neuro Sci. 39 (2): 189-95; 2012.

ZLOTKIN S.  Editorial More proof that home fortification is of value in children with iron deficiency anemia.  Arch Pediatr Adolesc Med, Vol. 266 (No.9), Sept. 2012.

Choudhury N, Aimone A, Hyder SMZ, ZLOTKIN, SH. Relative efficacy of micronutrient powders versis iron-folic acid tablets in controlling anemia in women in the second trimester of pregnancy. Food and Nutr Bull 33; 142-149, 2012.

Karakochuk C, van den Briel T, Stephens D, ZLOTKIN S.  Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with a corny-soya blend in children in southern Ethiopia:  an operations research trial.  Am J Clin Nutr 2012; 96:1-6.

Gavreau C, Unger W, Kohler J,  ZLOTKIN S. The Use of Cost-Effectiveness Analysis for Pediatric Immunization in Developing Countries. The Millbank Quarterly 2012; 90(4):762-90.

Zlotkin SH. Clinical Nutrition: The role of nutrition in the prevention of iron deficiency anemia in infants, children and adolescents. Can Med Assoc Journal 168:59-62, 2003.

Schauer C, Zlotkin SH. “Home-fortification” with Micronutrient Sprinkles – A New Approach for the Prevention and Treatment of Nutritional Anemias. Paediatrics and Child Health 8: 87-90, 2003.

Zlotkin SH, Kojo Yeboah Antwi, Claudia Schauer, George Yeung. Use of microencapsulated ferrous fumarate sprinkles to prevent recurrence of anemia in infants and young children at high risk. Bull World Health Organization 81:108-115, 2003.

Zlotkin S, Arthur P, Kojo Yeboah Antwi, Claudia Schauer, George Yeung Piekarz A. Randomized controlled trial of multi versus single-micronutrient supplementation for treatment of anemic infants. J Nutr 133:1075-1080; 2003

Liyanage C, Zlotkin SH. Bioavailability of iron from micro-encapsulated iron sprinkle supplement. Food and Nutrition Bulletin 23:2; p133-137, 2002.

Zlotkin SH, Arthur P, Antwi KY, Yeung G. Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as 'sprinkles' added to complementary (weaning) foods. Am J Clin Nutr 74: 791-795. 2001

Zlotkin SH, Arthur P, Antwi KY, Yeung G. Randomized controlled trial of single versus three-times daily ferrous sulfate drops for treatment of anemia. Pediatrics 108:613-616, 2001

Benoit D, Wang EEL, Zlotkin SH. Characteristics and outcomes of children with enterostomy feeding tubes: A study of 325 children. Paediatr Child Health 6:3, 132-137, 2001.

Weinstein M, Babyn P, Zlotkin SH. An Orange a Day Keeps the Doctor Away: Scurvy in the Year 2000. Pediatrics 108:3; 1-5, 2001.

Anderson GH, Zlotkin SH. Developing and Implementing Food-Based Dietary Guidance for Fat in the Diet of Children. Am J Clin Nutr 72(suppl):1404S-9S; 2000.

Yeung GS, Zlotkin SH. Efficacy of Meat and Iron-Fortified Commercial Cereal to Prevent Iron Depletion in Cow Milk-fed Infants Six to 12 Months of Age: A Randomized Controlled Trial. Can J Public Health 91:263-267; 2000.

Benoit D, Wang EL, Zlotkin SH. Discontinuation of Enterostomy Tube Feeding by Behavioral Treatment in Early Childhood: A Randomized Controlled Trial. J. Pediatr 137:498-503; 2000.

Zlotkin SH. Research Priorities in Complementary Feeding: Canadian Recommendations. Pediatrics 106:1272S-73S; 2000.