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About Sickkids
About SickKids

November 27, 2006

SickKids receives over $11 million in CFI Funding

Researchers at The Hospital for Sick Children (SickKids) will receive over $11 million in funding for infrastructure through the Canada Foundation for Innovations’ (CFI) inaugural New Initiatives Fund (NIF) and Leading Edge Fund (LEF) programs, announced today. Funding for these projects is part of a major $422,343,180 investment by the CFI to support 86 projects at 35 institutions across the country.

The Centre for the Study of Complex Childhood Diseases (CSCCD), led by Dr. Martin Post, head and senior scientist, Physiology & Experimental Medicine, professor of Paediatrics at the University of Toronto, will develop and study models of disease pathophysiology. This centre—the first of its kind in Canada—will involve multidisciplinary collaborations to promote sharing of new technologies, fostering the discovery of new interventional techniques developed by both basic and clinical researchers.

Using more than $8 million in infrastructure funding from CFI, the CSCCD will establish an animal physiological unit, a paediatric physiological unit, an analytical research laboratory, a tissue repository and a state-of-the-art imaging research facility capable of physiological and an interventional MRI.

A lot is known at the molecular and cellular levels; this centre will bring discoveries back to larger models. The centre will focus on complex childhood diseases such as asthma, cystic fibrosis, brain injuries and metabolic diseases including obesity.

The Centre for Investigation of Neuroplasticity and Developmental Disorders (CINDD) led by Dr. Carter Snead, senior scientist, Neurosciences & Mental Health, division head, Neurology, professor of Paediatrics at the University of Toronto, aims to position Canada as a leader in understanding the neuroplasticity of brain function. The CINDD, which includes collaborators at the University of Waterloo, will initiate new translational discoveries for a spectrum of disorders including epilepsy, development delay, and chronic pain, and create major health benefits for children.

The centre’s infrastructure comprises almost $3 million in advanced neuroimaging systems, including multiphoton microscopes, adaptive optics imaging, MEG. The centre will also share in the use of the interventional MRI included in the Post award. The CFI funding for CINDD will also support neurobehavioural lab systems for multidisciplinary research from the neuronal to cognitive network levels.

Non-invasive imaging and instrumentation shared between the two centres will promote translational science—interactions between the research and clinical aspects of discovery. Both the CINDD and CSCCD will be unprecedented research centres that will attract experts, trainees and funding.

SickKids also received funding through collaborations with other institutions. Cindy Guidos, senior scientist, Developmental & Stem Cell Biology, was awarded funds through John Dick’s Cancer Stem Cells project led by UHN. Julie Forman Kay, senior scientist, Molecular Structure & Function, is a principal user on the NMR Spectrometer Enhancement award which is led by Lewis Kay at the University of Toronto.