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About Sickkids
About SickKids

June 24, 2009

SickKids part of $6.4 million research grant

SickKids researcher, Dr. Philip Sherman, is part of a major $6.4 million grant from Ontario Research Fund announced June 23 by the Ministry of Research and Innovation.

Sherman, SickKids Senior Scientist, Cell Biology, at the Research Institute and Staff Gastroenterologist, is part of a collaborative project that aims to treat debilitating diseases such as inflammatory bowel disease (IBD) by developing new biological materials that can repair and regenerate damaged tissues. Sherman is also a Professor of Paediatrics, Microbiology and Dentistry at the University of Toronto, a Canada Research Chair in Gastrointestinal Disease and a Scientific Director with the Institute of Nutrition, Metabolism and Diabetes at CIHR.

The project, led by Dr. Michael Sefton of the University of Toronto, Institute of Biomaterials and Biomedical Engineering, is titled Therapeutic biomaterials for regenerative medicine. The total SickKids’ budget for this project is $2.9 million.

The research, a partnership with Toronto-based company Rimon Therapeutics Ltd., is based on using “therapeutic polymers” called Theramers™ which have biological activity and can be used to repair and regenerate diseased tissues without the use of cells, drugs or soluble factors. Such materials, regulated as devices, have potentially a shorter time to market than devices with cells or drugs.

The grant is part of the provincial government’s investment of $42 million to support the work of 15 Toronto-based research projects and more than 100 researchers. It is part of the government’s $94 million province-wide investment to support 31 world-class research projects and more than 300 researchers in seven communities across Ontario.

The research grant from Ontario Research Fund also supports SickKids’ researchers working with the Ontario Pre-Clinical Imaging Consortium project led by Sunnybrook Health Sciences Centre. The collaborators for this project are Dr. Mark Henkelman, Director, Mouse Imaging Centre, and Senior Scientist, Physiology & Experimental Medicine with the Toronto Centre for Phenogenomics (TCP), and also Professor, Medical Biophysics and Medical Imaging at University of Toronto; and Dr. John Sled, Scientist, Physiology & Experimental Medicine at the Research Institute, and Assistant Professor, Medical Biophysics at the University of Toronto. The total SickKids’ budget for this project is $1.5 million.