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CALIPER Project

Welcome to CALIPER, a nation-wide, multi-centre study spanning children's hospitals across Canada.

The CALIPER (Canadian Laboratory Initiative on Paediatric Reference Intervals) Project is a multi-centre, nation-wide initiative aimed at developing a comprehensive database of healthy reference values (reference intervals) for blood tests in children. The CALIPER Project is designed to fill the gaps that currently exist in paediatric reference intervals. 

To date, CALIPER has recruited over 9,000 healthy children from birth to 18 years of age that have donated a small sample of blood, which is used to develop gender- and age-specific reference intervals for multiple blood tests. CALIPER has already developed reference intervals for over 100 blood tests,  which can be used to improve diagnosis in many areas, including cardiology, nephrology, critical care and oncology. 

CALIPER will continue to work towards developing reference values for additional tests, and has made all data collected publicly available through an online database for doctors to use in their practice. The CALIPER reference intervals are being adapted by hospital laboratories across Canada and globally and helping to improve diagnosis and monitoring of children with medical concerns.