The Division of Infectious Diseases was established on May 1, 1979, under the leadership of Dr. Ronald Gold. The division is one of the oldest and largest in North America. We provide a consultation service to all divisions and departments in the hospital by providing evaluation and management advice on infections, infectious diseases, and infection prevention and control. A major area of involvement is the immunocompromised host, particularly those with malignancies, transplants and HIV. Outpatient care is mainly focused on tuberculosis, HIV, congenital infections, and follow-up of osteomyelitis.
The division is fully accredited by the Royal College of Physicians and Surgeons of Canada as a training program in Paediatric Infectious Diseases. The members of the division are actively involved in teaching at undergraduate, graduate and post-graduate levels at The University of Toronto. Our research initiatives are structured around themes that include host susceptibility and related factors and innovative antimicrobial and associated therapies. Specific research initiatives include multicentered paediatric HIV studies related to maternal-to-child transmission and studies on new antiretrovirals, vaccine studies and research into the mechanisms of host susceptibility to viral infections. These infections include viral myocarditis, HIV and EBV-related post-transplant lymphoproliferative disease (PTLD) and encephalitis. Multicentered trials related to the diagnosis and prevention of infections in transplant patients are ongoing, as well as participation in national surveillance studies through the Immunization Programme Active (IMPACT) and national collaborative Paediatric studies through the Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC). Our research in Infection Control includes the clinical and molecular epidemiology of paediatric nosocomial infections.