Treatment of Bone Marrow Failure and Myelodysplasia (Pre-leukemia) Syndromes
Children and adults with bone marrow failure and MDS have low blood counts and are at high risk of developing leukemia. The various disorders are individually rare, however when combined together they constitute an important portion of the pediatric hematology/oncology practice.
In the Marrow Failure and Myelodysplasia Program patients receive treatment based on either cutting-edge standard-of-care guidelines or research protocols.
The standard of care or research protocols include therapies such as:
- platelet and blood transfusion
- growth factors, for example, G-CSF
- corticosteroids such as prednisone
- androgens such as oxymethalone
- Immunosuppressive therapy (ATG and cyclosporin)
- hematopoietic stem cell transplantation from related or unrelated donors. Sources are bone marrow, peripheral blood or cord blood. This treatment is given in our highly-qualified and highly experienced blood and marrow transplantation unit.