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Awards 2002-2003

Research and Investigations

A population based cohort study of incidence, health care utilizations and outcomes in children with stroke. deVeber GA, To T: Canadian Institute of Health Research ($199,152 2002 – 2004)

The Children’s Stroke Project. deVeber GA: Anonymous Children’s Foundation ($1,850,000 2001 – 2006)

Towards the establishment of standards of practice and the initiation of multi-centre, multi-national clinical trials for neonates and children with stroke. deVeber GA, Ashwal S, Ferriero D,Ichord R, Kirkham F, Lynch J, O’Callaghan F, Pavlakis S, Roach S, Sebire G, Willan A: Child Neurology Society/Child Neurology Foundation Multicentre Clinical Research Grant ($118,102 2002 – 2004)

Theme II: Optimizing acute stroke care in Canada. Networks of Centres of Excellence, Canadian Government (no funds committed to G. deVeber). deVeber GA and 138 Canadian stroke researchers: Canadian Stroke Network ($4,700,000 2000 – 2007)

A double blind placebo controlled randomized clinical trial of fluroxamine and sertraline in childhood autism. Vohra S, Balthazor M, Roberts W: Ontario Mental Health Foundation ($114,688 2000 – 2003)

A multicenter, double-blind, placebo-controlled, randomized trial and an open-label long-term tolerability trial of Zolmitriptan (ZOMIG). MacGregor DL: Astra-Zeneca Pharmaceuticals, Inc. ($15,500 1999 – 2002)

A randomized double-blind trial on add on flunarizine to prevent the cognitive deterioration associated with infantile spasms. Carmant L, Weiss SK: CIHR ($410,000 2003 – 2006)

Atypical Absence Epilepsy: GABAB. Snead OC, Cortez M, Francis E: CIHR ($330,000 2000 – 2003)

Carnitine-responsive cardiomyopathy and the different-affinity carnitine transporters. Tein I: Heart and Stroke Foundation of Ontario Grant-NA 4964 ($154,000 2002 – 2004)

Characterization of patients with childhood autosomal recessive muscular dystrophy. Vajsar J: The Hospital for Sick Children Foundation ($37,900 2000 – 2003)

Clinician Scientist Start-up funds to hire project co-ordinator for Childhood Stroke Research program. deVeber, GA: Hospital for Sick Children Research Institute ($50,000 1999 – 2003)

Commercial applications of gene discovery in the progressive myoclonus epilepsies: From clinical and prenatal diagnosis to protein replacement therapy. Minassian BA: Canadian International Development Agency ($30,000 2002 – 2003)

EEG changes with vagus nerve stimulation. Betty Koo, David Adelson, Brent Tarver: Cyberonics ($450,000 2002 – 2004)

Examination of auditory function in children using MEG. Pang E, Otsubo H, Sharma R, Chuang S: Seed Grant at the Hospital for Sick Children ($19,210 2002 – 2003)

Exploring the gap between knowledge and behavior: A qualitative study of clinician action following an educational intervention. Kennedy T, Lingard, L, Rosenfield J, Roberts W: Physicians Services Incorporated ($7,800 2001 – 2003)

Exploring the gap between physician knowledge and behavior: A qualitative study of clinician action following an educational intervention. Kennedy T, Lingard L, Rosenfield J, Roberts W: CIHR-ACMC ($19,4922001 – 2003)

Generation of carnitine transporter OCTN1 knock-out mouse. Tein I: Hospital for Sick Children Foundation Grant ($60,000 2002 – 2003)

Genetic characterization of congenital muscular dystrophies. Brais B, Banwell B, Hawkins C, Vanasse M, Houde S, Bouchard JP, Mathieu J, Karpati G: The Muscular Dystrophy Association of Canada ($100,000 2003 – 2005)

Genetic epidemiology of autism: Family and molecular studies. Szatmari P, Bryson S, Goldberg J, Patterson A, Mahoney W, Merette C, Zwaigenbaum L, Scherer S, Roberts W: Canadian Institute of Health Research ($725,000 2003 – 2008)

Genetics of ADHD. Barr C, Schachar R, Roberts W, Malone M, Tannock R, Kennedy J: Psychiatry Endowment Fund, The Hospital for Sick Children ($12,680 1997 – 2002)

HEIDI: Healthcare Equity for Intellectually Disabled Individuals. Holden JJA, Benser FP, Yu DCT, Morin D, MacGregor DL: Canadian Institutes of Health Research ($100,000 2003 – 2004)

Hydrocephalus: MRI morphometric and cognitive correlations. Dennis M, MacGregor DL: National Institute of Health ($1,131,141 1998 – 2003)

Identifying early markers of autism: A longitudinal study of infant siblings. Zwaigenbaum L, Szatmari P, Bryson S, Roberts W: National Alliance Autism Research ($250,000 2001 – 2003)

Impact of non-invasive ventilation on children and adolescents with neuromuscular conditions. Katz S, Banwell B, MacLusky I, Nicholas D, Vajsar J, Keilty-Lau K, Mitchell M, Boyd J, Anderson P, Balthazor M: Children Foundation ($70,000 2002 – 2004)

Localization brain language in a normal pediatric population: a comparison of functional magnetic resonance imaging (fMRI) and magnetoencephalography/ magnetic source imaging (MEG/MSI) techniques. Logan W, Pang E, Otsubo H: Pediatric Consultants, Research Proposal at the Hospital for Sick Children ($5,000 2002 – 2003)

MEG normal data of children: Functional mapping somatosensory cortex. Xiang J, Otsubo H, Wilson D, Holowka S, Sharma R: Seed Grant – The Hospital for Sick Children ($19,210 2002 – 2003)

Melatonin for sleep induction: Chloral hydrate versus melatonin, randomized controlled study. Weiss SK, Wassmer E, Otsubu H, Koren G, Chu B, Yves S: HSC Research Institute 2003 Seed Grant Competition ($11,430 2003 – 2004)

Mitochondrial encephalomyopathies – MELAS Dichloroacetate Trial. De Vivo DC, Tein I (External Medical Review and Advisory Committee): National Institutes of Health Grant (NICHD) ($1,144,125 1999 – 2004)

Molecular genetics and functional studies in Lafora’s progressive myoclonus epilepsy. Minassian BA: Canadian Institute of Health Research ($866,680 2000 – 2005)

Murine knockout of 4-hydroxybutyrate. Snead OC, Gibson M: NIH ($504,000 2000 – 2004)

Neural correlates of auditory processing in autism and language disorders. Roberts SW, Oram J, Roberts T: Canadian Institute of Health Research, Postdoctoral fellowship for Janis Oram ($80,000 2003 – 2005)

Neurobehavioural outcome of head injury in children – Subcontact $279,021. Dennis M, MacGregor DL: NINDS ($5,186,891 1998 – 2004)

Neuroimaging. Snead OC: Ontario Research Development Challenge Fund ($800,000 2001 – 2006)

New defects of polyamine metabolism. Hyland K, Baylor University, Dallas, Texas, Tein I (Consultant): National Institutes of Health Grant (NINDS) ($869,535 2001 – 2004)

Optimizing primary stroke prevention in children with sickle cell anemia (STOP II). Olivieri N, MacGregor DL: NIH ($195,951 2000 – 2005)

Is lipoprotein (a) a risk factor for recurrent ischemic stroke in children. deVeber GA, Chan AK, Connolly P: Canadian Stroke Network ($45,000 2003 – 2004)

Quality of life for children with longterm disabilities: Instrument development and validation. Renwick R, Friefeld F, Rosenfield J, Raphael D, Brown I: Hospital for Sick Children Foundation ($84,934 2000 – 2002)

Raising serum free polyunsaturates in humans and breath acetone. Cunnane S, Curtis R: Natural Sciences and Engineering Research Council ($317,000 2001 – 2003)

Research Fellowship Award (Dr. M. Frantseva). Snead OC: CIHR – Fellowship Award ($38,500 2001 – 2004)

Role of the carnitine/organic cation transporters in the mammary gland and implications for the suckling infant. Tein Ingrid: Mead-Johnson Grant ($7,500 2003 – 2004)

Serotinergic mechanisms in atypical absence seizures. Snead OC: Hospital For Sick Children, Paediatric Consultants ($5,000 2001 – 2002)

Stroke Investigators Award Research Scholar. deVeber GA: Heart and Stroke Foundation ($260,000 2001 – 2006)

The investigation of genetic factors in ADHD. Barr C, Ickowicz A, Kennedy J, Malone M, Roberts W, Schachar R, Tannock R: Canadian Institute for Health Research ($1,159,600 2002 – 2005)

The role of defective carnitine transport in male infertility. I Tein: Physicians’ Services Incorporated Foundation of Ontario Grant, ($164,000 2001 – 2003)

Training Program In Autism Research. Eric Fombonne, Fombonne E, Paterson A, Scherer S, Roberts W, Smith I, Moore C et al: Canadian Institute Health Research, National Alliance for Autism Research, Fonds de la Recherche en Sante du Quebec ($1,440,000 2003 – 2009)

Using event-related potentials (ERP) to characterize auditory processing deficits in autism spectrum disorders and Landau-Kleffner syndrome. Pang EW, Logan WJ, Roberts W: Cure Autism Now Foundation ($80,000 2002 – 2004)

Virological and immunological features of paediatric multiple sclerosis. Banwell B, Bar-Or A, Krupp L: Wadsworth Foundation ($506,000 2002 – 2005)

Virological studies in pediatric multiplesclerosis. Banwell B, Al-Otaibi S, Tellier R: Directed donation of The Hospital for Sick Children Foundation ($8,000, 2002 – 2003)

Visual function in infants and children treated with vigabatrin. Snead OC (Co-PI), Westall C, Logan W CIHR: ($300,000 2001 – 2004)