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Metabolic Bone Health Unit

Who is at risk of osteoporosis?

  1. Children with certain Chronic Illnesses

Chronic illness

Associated risk factors

Juvenile idiopathic arthritis
Connective tissue diseases
Chronic inflammation, glucocorticoids and other medications, immobilization
Neuromuscular disordersImmobilization, decreased muscle mass and muscle strength
Inflammatory bowel diseases
Celiac disease, Cystic fibrosis
Glucocorticoids, chronic inflammation,
Eating disordersMalnutrition, low calcium and vitamin D intake, hypogonadism
Solid organ transplantationGlucocorticoids and other immunosuppressive medication
Bone marrow transplantation
Medications, radiation therapy, low physical activity, endocrine late effects
Endocrine disordersHypogonadism, growth hormone deficiency, glucocorticoid excess
  1. Children with recurrent fractures (>4)