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Arthur & Sonia Labatt Brain Tumour Research Centre

BTRC News 2007

November 2007

Michael Taylor, neurosurgeon from The Hospital for Sick Children, is the first Canadian to be awarded a three year grant from the Sontag Foundation of the United States.http://www.sontagfoundation.com.

His project entitled “Multiple Genetic Events Converge to Target Histone 3 Lysine 9 Methylation in Pediatric Medulloblastoma” was one of three projects awarded in North America.

For his success with the Sontag Foundation, we congratulate Michael Taylor.

February 2007

In 1997, the Labatts presented SickKids with an unprecedented donation of $5 million to help establish the world-leading Arthur and Sonia Labatt Brain Tumour Research Centre. As the first centre of its kind in Canada dedicated to basic science and the first in North America to focus on both paediatric and adult brain tumours, the goal was to create an institution where scientists and clinicians from SickKids, the University Health Network and the University of Toronto could share ideas, resources and equipment, and integrate groundbreaking lab research with patients being treated at SickKids.

An additional $5 million from today’s gift will go towards the Arthur and Sonia Labatt Brain Tumour Research Centre, increasing their support that has transformed the understanding of and ability to treat brain tumours.

"Since our first investment in SickKids 10 years ago, we have witnessed results from Rutka and his team that are above and beyond anything we had anticipated," said Arthur Labatt. "This concrete impact on both their medical advances and scientific discovery inspired us to build on these strengths with our continued support of the Brain Tumour Research Centre and the establishment of the Paediatric Heart Centre. Our hope is that the new heart centre under the able guidance of Redington will not only help hundreds of children from across Canada who suffer from congenital heart disease, but through its cardiovascular research, will further the understanding of paediatric cardiology around the world."

Arthur Labatt co-founded Trimark Financial Corporation, now AIM Trimark Investments, one of Canada’s largest mutual fund companies. He was elected to Fellowship of the Institute of Chartered Accountants of Ontario in March 1997. Highlights of his volunteer activities include directorships at SickKids Foundation, Parkinson Foundation of Canada, Canadian Opera Company, Young People’s Theatre, Toronto French School and the African Medical and Research Foundation. In October 2004, Mr. Labatt was installed as Chancellor of the University of Western Ontario, a position he continues to hold today. For his outstanding business and community leadership, Mr. Labatt was named an Officer of the Order of Canada in July 1996.

Sonia Labatt is an Associate Faculty Member at the Centre for Environment at the University of Toronto. Both her teaching and research focus on issues of corporate environmental management. Labatt’s volunteer activities included directorships at the National Ballet of Canada and the Wellesley Hospital Foundation. She also was a director of the Art Gallery of Ontario and co-chaired Havergal College’s ‘Fund for Tomorrow’ campaign. Currently, Labatt is a director of World Wildlife Fund Canada, sits on the Dean’s Advisory Board, Faculty of Arts and Science, University of Toronto and is a member of the Board of Trustees at SickKids.

January 2007

Uri Tabori will join the Arthur and Sonia Labatt Research Centre as a Scientist and Principal Investigator in the fall of 2007.

Tabori received his MD degree from Hadassah School of Medicine, Hebrew University, in Jerusalem, Israel. He then completed his paediatrics in Sorasky Medical Center, Tel-Aviv; and paediatric hematology/oncology Chaim Sheba Medical Center, Tel-Hashomer, Israel. Tabori then came to SickKids in 2003 to undertake a three-year postdoctoral research fellowship in neuro-oncology under the guidance of Drs. Eric Bouffet and David Malkin.

While working in the laboratory, Tabori identified that maintenance of telomeres in paediatric low grade gliomas and ependymomas is inversely correlated with patient outcome

At the present time, Tabori’s research focuses on mechanisms which enable tumors to recur and continue to progress. Tabori hopes to utilize his research efforts now to identify novel therapeutic approaches to help children with brain tumours. Welcome Uri!