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Childhood CNS Vasculitis

Primary and secondary CNS vasculitis 

CNS vasculitis often affects previously healthy children. If the inflammation solely targets the blood vessels of the brain and/or spinal cord in these children, the disease is then referred to as primary CNS vasculitis or childhood Primary Angiitis of the CNS (cPACNS). 

All children require a careful assessment for an associated systemic illness such as an infection, rheumatic disease or malignancy. Children who develop CNS vasculitis in the context of an underlying illness are considered to have Secondary CNS Vasculitis.  

Childhood CNS Vasculitis tree diagram

More information on differential diagnoses and mimics of Childhood CNS Vasculitis can be found here.