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Secondary CNS Vasculitis

Children ≤18 years of age are diagnosed with secondary CNS vasculitis if they have evidence of 

  • Any newly acquired focal and/or diffuse neurological and/or psychiatric deficit plus 
  • Angiography and/or brain biopsy evidence of CNS vasculitis
  • In the presence of an underlying systemic condition such as an infection, rheumatic disease or other

Secondary CNS vasculitis can be caused by  a large number of underlying conditions. Infection is the most common cause for secondary CNS vasculitis.  A thorough evaluation for an underlying systemic condition is required when a child presents with newly acquired neurological and/or psychiatric deficit.