Analytical Facility for Bioactive Molecules (AFBM)
The Analytical Facility offers a range of services for quantitative and qualitative analysis of biological samples to the greater scientific community.
Services
Mass Spectrometry
- LC-MS-MS / GC-MS
- Maldi - MS imaging
- Quantitative and investigative analysis of small molecules - metabolites, lipids, amino acids, eicosanoids and drugs
Customized Methods
- Stable isotope metabolic pathway tracing
- Molecular tissue imaging - spatial arrangement and relative abundances of metabolites, drugs, phospholipids, peptides and proteins in tissue samples
- Bio-Analytical
- HPLC-PDA, UV, Vis, fluorescence and ECD
- Nano-HPLC
- ProteomeLab PF 2D
- Luminex – immunoassays, receptor-ligand, molecular biology and enzymatic
- ProteOn – protein/protein interactions
Contact Information
Mass Spectrometry
Michael Leadley
Monday to Friday, 10 a.m. to 6 p.m.
Tel: 416-813-8706
email: michael.leadley@sickkids.ca
Bio-Analytical
Denis Reynaud
Monday to Friday, 9 a.m. to 5 p.m.
Tel: 416-813.8707
email: dreynaud@sickkids.ca