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Research Programs

Scientist/Clinician-Scientist, Protein-RNA Interactions and Assembly

The Hospital for Sick Children (SickKids) Research Institute seeks an outstanding scientist or clinician scientist focused on studies of protein-RNA interactions within micron-scale assemblies and their roles in biology and disease. This position is at the interface between biophysics and cell biology, building on recent discoveries that many cellular bodies and biomaterials are generated by phase separation of protein, often with RNA. The position is at the Scientist level with cross-appointment at the Assistant Professor level to an academic department at the University of Toronto. SickKids is a world renowned Children’s Hospital with seven fully integrated research programs. The appointee will be located in our 21-storey state-of-the-art SickKids Research & Learning Tower in the Discovery District of downtown Toronto, offering a unique environment for medical science discoveries in close proximity to seven other academic hospitals/research centres and Canada’s largest university.

The successful candidate is expected to establish a world-leading research program in the area of higher order protein-RNA association with the intent of elucidating fundamental mechanisms of RNA processing and how these processes become altered in disease. While this area has implications for much of biology, priority will be given for applications to cellular RNA processing and regulation, including control of transcription, splicing and translation, that are essential for understanding and treating cancer and neurodevelopmental disorders. In vitro biophysical, biochemical, cell-based and computational approaches are of primary interest, but other approaches will be considered.

Candidates must have a PhD, MD*, or MD*/PhD, significant postdoctoral experience and a record of scientific accomplishments in the aforementioned research areas. The successful candidate will initiate and maintain an original, competitive, and independently funded research program of international calibre. Potential for collegial interaction will be an important element in attaining the position. The successful candidate will benefit from the extensive research and core facilities of SickKids, the University of Toronto and its affiliated institutions for structure, biophysics, cellular imaging, genomics, proteomics and bioinformatics, as well as inter-institutional initiatives focused on RNA and on phase separation. Salary will be commensurate with qualifications and experience within the range of 120K – 200K CAD. A competitive benefits package is being offered along with support for relocation expenses.

Interested individuals should submit their application in PDF format, to: Chair, Protein-RNA Assembly Search Committee at proteinrna.facultyrecruitment@sickkids.ca. Applications should include: curriculum vitae, description of past research (maximum 1 page), proposed research program (Maximum 3 pages) and copies of three representative publications. Applicants should arrange to have three signed letters of reference sent directly by the referee to proteinrna.facultyrecruitment@sickkids.ca, indicating the applicant’s name in the subject line.

Applicants may direct any informal enquires to:
Protein-RNA Assembly Search Committee
SickKids Research Institute
The Peter Gilgan Centre for Research and Learning
686 Bay Street, RM 20.9702
Toronto, Ontario
M5G 0A4

* Wherein a practicing MD, the successful candidate will have obtained an appropriate Certificate of Registration from the College of Physicians and Surgeons of Ontario (license to practice), and appropriate VISA, if applicable.

Applications will be accepted until November 10, 2017.

SickKids is strongly committed to diversity within its community and especially welcomes applications from members of visible minorities, women, persons with disabilities, Aboriginal persons and others who may contribute to diversity within our organization. All qualified candidates are encouraged to apply; however, candidates legally eligible to work in Canada and permanent residents of Canada will be given priority. Only those applicants selected for the interview will be contacted.