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Translational Medicine

Doria Lab

Principal Investigator

Andrea Doria, MD, PhD, M.Sc.

Research Activities

My main research interests involve the investigation of potential imaging markers to test measurement properties (reliability, validity, responsiveness, sensitivity, specificity) to track angiogenesis-related factors (cause) and early cartilage degeneration (effect) in musculoskeletal disorders in the paediatric population using novel MRI and ultrasound techniques.


Doria AS, Lundin B, Kilcoyne RF, Babyn PS, Miller S, Nuss R, Rivard G, Stephens D, Pettersson H. Reliability of progressive and additive MRI scoring systems for evaluation of haemophilic arthropathy in children: Expert MRI Working Group of the International Prophylaxis Study Group. Haemophilia. 2005;11(3): 245-53

Lundin B, Nuss R, Kilcoyne R, Doria AS, Babyn PS, Miller S, Rivard G, Ljung R, Pettersson H. Compatible scales for progressive and additive magnetic resonance imaging assessments of haemophilic arthropathy. Haemophilia 2005; 11 (2): 109-115

Doria AS, Dick PT. Region-of-interest-based analysis of clustered BOLD MRI data in experimental arthritis. Acad Radiol 2005; 12 (7): 841-852

Doria AS, Castro CC, Kiss MH, Sernik RA, Vitule LF, Silva CHM, Zerbini CAF, Arantes PR, Lucato L, Germano MAN, Cerri GG. Inter- and intra-reader variability in the interpretation of two radiographic classification systems for juvenile rheumatoid arthritis. Pediatr Radiol 2003; 33 (10): 673-681

Doria AS, Babyn PS, Crawley A, Noseworthy M, Pritzker K, Salter RB. Understanding the functional angiogenic process in an antigen-induced arthritis model: correlative BOLD MR Imaging (fMRI) of the stages of synovitis along the time course of the disease. (abstract) Radiology 2002; 225 (P): 379

Doria AS, Babyn PS, Burns P, Kharchakdjian R, Mohanta A, Holowka S. Contrast-enhanced triggered harmonic sonography for quantification of synovial blood flow in an antigen-induced arthritis model: preliminary results of microbubble destruction-reperfusion and wash-in / wash-out curves. Pediatr Radiol 2002; 32 (Suppl. 1): S53

Doria AS, Guarniero R, Cunha FG, Modena M, Godoy Jr. RM, Luzo C, Boelliger Neto R, Molnar LJ, Cerri GG. Contrast-enhanced power Doppler sonography: assessment of revascularization flow in Legg-Calve-Perthes’ disease. Ultrasound Med Biol 2002; 28 (2): 171-182

Doria AS, Guarniero R, Godoy Jr. RM, Buchpiguel C, Modena M, Cunha FG, Luzo C, Molnar LJ, Sapienza MT, Cerri GG. Contrast-enhanced power Doppler US: comparison with scintigraphic phases of revascularization of the femoral head in Legg-Calve-Perthes’ disease. J. Pediatr. Orthop. 2002; 22 (4): 471-478

Doria AS, Kiss MH, Lotito APN, Molnar LJ, Castro CC, Medeiros CC, Cerri GG. Juvenile rheumatoid arthritis of the knee: evaluation with contrast-enhanced color Doppler US. Pediatr. Radiol. 2001; 31 (7): 524-531

Doria AS, Guarniero R, Molnar LJ, Modena M, Cunha FG, de Godoy Jr. R, Cerri GG. Three-dimensional (3D) contrast-enhanced power Doppler imaging in Legg-Calvé-Perthes disease. Pediatr. Radiol. 2000, 30 (12): 871-874

Contact Information

Senior Secretary
Seetha Srirahan
e-mail:  seetha.srirahan@sickkids.ca 

Mailing Address
Peter Gilgan Research and Learning Centre
686 Bay St. Room 08.9710
Toronto, ON M5G 0A4

Tel.: (416) 813-7654 ext. 306079
Fax: (416) 813-7591
e-mail: andrea.doria@sickkids.ca