Douglas Cheyne, PhD
Research Institute
Senior Scientist
Neurosciences & Mental Health
University of Toronto
Associate Professor, Institute of Biomaterials and Biomedical Engineering
Department of Medical Imaging
Phone: 416-813-2168
Fax: 416-813-7362
e-mail: douglas.cheyne@sickkids.ca
Brief Biography
Dr. Cheyne (PhD, 1988, Simon Fraser) is a neuroimaging scientist with a specialization in Magnetoencephalography (MEG). His postdoctoral work at the Neurological Clinical at Vienna General Hospital focused on the application of MEG to the study of human motor control. Dr. Cheyne subsequently worked in the MEG industry in Canada and has held adjunct appointments in Kinesiology and Psychology at Simon Fraser University. He joined the SickKids Research Institute as a Senior Scientist in 2001. Dr. Cheyne is an Associate Professor of Medical Imaging at the University of Toronto with cross-appointments in the Institutes of Biomaterials and Biomedical Engineering and Medical Sciences. His current research is focused on the advancement of neuroimaging techniques for the diagnosis of childhood epilepsy, presurgical functional mapping, and the study of sensory, motor and cognitive processes and their impairments in children and is supported by grants from CIHR, NSERC, and the Canadian Foundation for Innovation.
Research Interests
- Imaging techniques in neuroscience (EEG, MEG and fMRI)
- Mathematical modeling of the electrical activity of the brain
- Motor and sensory systems
- Cognitive neuroscience
Research Activities
My research is focused on the development of neuroimaging methods using Magnetoencephalography (MEG) – a new imaging technology that monitors brain function non-invasively, by detecting small magnetic fields produced by neural activity. We use mathematical models to localize the generators of the measured fields to produce images of activity patterns throughout the brain. This neuromagnetic imaging method has applications in the diagnosis of abnormal brain activity in disorders such as childhood epilepsy, as well as aiding in the localization of various functional cortical areas prior to surgery. My laboratory is currently developing new analysis methods for the application of neuromagnetic imaging to the study of various sensory, motor and cognitive processes and their impairments in adults and children.
Future Research Interests
Projects currently underway include: development of MEG imaging methods for cognitive brain imaging; application of MEG techniques in epilepsy; measuring cortical oscillatory activity associated with proprioception and movement; localization of neural activity associated with visual motion and visuomotor integration.
External Funding
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Canadian Institutes of Health Research (CIHR)
- Canadian Foundation for Innovation
Publications
Cheyne D, Bells S, Ferrari P, Gaetz W, Bostan AC. (2008) Self-paced movements induce high-frequency gamma oscillations in primary motor cortex. NeuroImage 42:332-342.
Pang EM, Drake JM, Otsubo H, Martineau A, Strantzas S, Cheyne D, Gaetz W. (2008) Interoperative confirmation of hand motor area identified preoperatively by magnetoencephalography: a clinical case study. Pediatric Neurosurgery 44:313-317.
Virji-Babul N, Moiseev A, Cheung T, Weeks D, Cheyne D, Ribary U. (2008) Changes in Mu rhythm during action observation and execution in adults with Down syndrome: implications for action representation. Neuroscience Letters 436: 177-180.
Sutcliffe TL, Gaetz W, Logan W, Cheyne D, Fehlings DL. (2007) Cortical reorganization after modified constraint-induced therapy in pediatric hemiplegic cerebral palsy. Journal of Child Neurology 22: 1281-1287.
Cheyne D, Bostan AC, Gaetz W, Pang EW. (2007) Event-related beamforming: a robust method for presurgical functional mapping using MEG. Clinical Neurophysiology 118:1691-1704.
Herdman T, Pang E, Gaetz W, Ressl V, Cheyne D. (2007) Spatiotemporal dynamics of neuromagnetic responses related to language production. Cerebral Cortex 17: 2536-2543.
Martinez-Trujillo J, Cheyne D, Gaetz W, Simine E, Tsotsos J. (2007) Activation of MT/V5+ and right inferior parietal cortex during the detection of transient direction changes in translational motion. Cerebral Cortex 17:1733-1739.
Itier RJ, Herdman AT, George N, Cheyne D, Taylor MJ. (2006) Inversion and contrast-reversal effects of face processing assessed by MEG. Brain Research 1115: 108-120.
Cheyne D, Bakhtazad L, Gaetz W. (2006) Spatiotemporal mapping of cortical activity accompanying voluntary movements using an event-related beamforming approach. Human Brain Mapping 27: 213-229.
Kelso JAS, Fuchs A, Lancaster R, Holroyd T, Cheyne D, Weinberg H. (1998) Dynamic cortical activity in the human brain reveals motor equivalence. Nature 392: 814-818.