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CF Cell Lines Available

CF Cell Lines Available

The CF Canada-Sick Kids Program for Individual CF Therapy is now providing samples to CF researchers for academic, non-commercial research purposes. Both CF patient iPS cells and matched patient nasal cells are available. If you wish to receive samples for your research please complete the samples request form and send it as an attachment to peckford@sickkids.ca. Your request will be reviewed by the sample committee in terms of scientific merit and feasibility, and by SickKids Research Ethics Board, if appropriate, before any samples will be delivered. Successful applicants will be required to sign a license agreement.

Collection of samples and initial generation of the cell lines is supported by the CF Canada-SickKids Program in Individualized CF Therapy. Researchers will be charged a fee per nasal cell sample and per iPS cell sample, (plus shipping) to cover costs of sample expansion/aliquot preparation to share these lines.  

The fee is currently $500 per line requested.  

**NOTE: only academic researcher requests for samples for non-commercial purposes may be granted at this time**

Contact the Program Manager, Dr. Paul Eckford, peckford@sickkids, for further information.  

Currently available genotypes for both nasal cells and iPS lines:

-Non-CF/control
-F508del homozygous (multiple lines)
-A small selection of rare mutations (homozygous)

Each line will be provided with a cell line information sheet describing generation of the cell line, genotype, characterization done with that cell line, and thawing and maintenance instructions.  

For further information, please contact the Program Manager, Dr. Paul Eckford, peckford@sickkids.ca.