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Garron Family Cancer Centre


Policy and Economics Research in Childhood Cancer (PERCC)
Goals of PERCC
Strategies to Achieve Goals
PERCC Sponsors
Dr. Gupta discusses PERCC (Video)

Policy and Economics Research in Childhood Cancer (PERCC)

Over 80% of children with cancer live in low- and middle-income countries (LMICs); their cure rates lag far behind those of children in high-income countries (HICs). National Childhood Cancer Strategies hold the potential to increase childhood cancer cure rates across large LMIC populations, but are in place in only a handful of LMIC. Barriers to adoption include a lack of health policy, health economics and implementation research relevant to LMIC paediatric oncology. Through a collaborative approach PERCC will support LMICs in an effort to overcome these barriers.


Goals of PERCC:

  • Conduct health policy and health economics research relevant to the care of children with cancer in LMICs
  • Use the results of such research to inform advocacy and policy efforts at various national and international levels

Strategies to Achieve Goals:

  • Forming associations with both national and international stakeholders
  • Leveraging partnerships with various LMIC childhood cancer centres
  • Obtaining competitive grant funding and support through philanthropic sources
  • Building capacity for health policy and health economics research through graduate and post-graduate level training of individuals from both HICs and LMICs

PERCC Sponsors:

Garron Family Cancer Centre

Centre for Global Child Health

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November 2017 – Update

11th International Conference on Cancer in Africa (AORTIC 2017): November 7-10 Kigali, Rwanda
Members of the PERCC Team participated in the biennial AORTIC International Conference on Cancer in Africa hosted by the African Organisation for Research and Training in Cancer (AORTIC).  AORTIC is a pan-African, bilingual, multi-disciplinary organization dedicated to the promotion of cancer care and control in Africa.

Watch Dr. Denburg and Dr. Gupta’s interviews below:

Treating Burkitt's lymphoma in Kampala – Dr. Avram Denburg
Treating Burkitt S Lymphoma In Kampala
Access to Essential Paediatric Medicines

Affordability of childhood cancer treatments – Dr. Sumit Gupta
Adapting UICC Guidelines for Low Resource Settings

Affordability of Childhood Cancer Treatments

September 2017

Lancet Oncology Commission on Sustainable Paediatric Cancer Care Meeting held at SickKids - September 7-9, 2017
Read more about this meeting on SickKids News “Treating the gaps in childhood cancer care

Watch the Lancet Oncology Commission on Sustainable Paediatric Cancer Care Panel held on Friday, September 8, moderated by Dr. Sumit Gupta

Program Program - PDF

June 2017
New Publication!

Improving childhood cancer care in Latin America and the Caribbean: a PAHO Childhood Cancer Working Group position statement. Avram Denburg, Cristóbal Cuadrado, Cheryl Alexis, Federico Antillón Klussmann, José Carlos Barrantes Zamora, Curt Bodkyn, Myriam Campbell Bull, Gustavo Dufort y Alvarez, Latoya Gooding, Tezer Kutluk, Silvana Luciani, Jessyca Karina Manner Marcillo, Sandro Martins, Monika Metzger, Anyul Milena Vera, Florencia Moreno, Jabibi Noguera, Armando Pena Hernandez, Karina Quintero Delgado, Michelle-Ann Richards-Dawson, Marcelo Scopinaro, Jaime Shalkow Klincovstein, Corrine Sinquee-Brown, Amaranto Suarez, Julie Torode, Caridad Verdecia, Roberto Franklin Vásquez, Sumit Gupta. The Lancet Oncology, Volume 18, Issue 6, p709-711, June 2017.

May 2017
Pan American Health Organization (PAHO) - Regional Childhood Cancer Task Force Meeting Report now available.

February 2017
PAHO Regional Childhood Cancer Task Force meeting in Washington

Regional experts on childhood cancer join forces to reduce inequities and increase access to care

Click on thumbnails below for larger image.


January 2017
New Publication!

Denburg AE, Arora B, Arora RS, Auste C, Bagai P, Barr R, Challinor J, Eden T, Grynzspancholc E, Hoffman R, Link M. Access to essential medicines for children with cancer: A joint SIOP-CCI position statement. Lancet Oncology 2017;18:20-22.

Denburg AE, Wilson MG, Johnson S, Kutluk T, Torode J, Gupta S. Advancing the development of national childhood cancer care strategies in Latin America. Journal of Cancer Policy 2017; 12: 7-15.

Pediatric Cancer Working Group for Latin America and the Caribbean:
PERCC is collaborating with PAHO, UICC and the University of Chile to co-convene and help lead a Pediatric Cancer Working Group for Latin America and the Caribbean, which will hold its inaugural meeting on Feb 2-3, 2017 at the PAHO headquarters in Washington, DC. The meeting brings together MoH representatives from 20 countries in the region to share experiences and challenges faced regarding the provision of childhood cancer care, and to strategize about national and regional approaches to improving systems of care in Latin America and the Caribbean.

July 2016
The Lancet Oncology Commission on Sustainable Paediatric Cancer Care

Launching in 2018, The Lancet Oncology Commission on Sustainable Paediatric Cancer Care is a joint partnership between PERCC, St. Jude Children’s Research and Hospital and the Harvard T.H. Chan School of Public Health. The Commission will undertake a comprehensive analysis to develop an investment case for funding management and control of childhood cancer. Cancer kills more than 100,000 children each year, and yet 80% of paediatric cancers are treatable with currently available interventions. Notably, the majority of these deaths occur in low-to-middle-income countries (LMIC) where children have poor access to health services. It is crucial that as countries transition to universal health care, childhood cancers are recognised as a priority for inclusion in benefits packages. Yet no reliable data are available in LMIC on current and future burden of childhood cancer; on cost of effective interventions; on current coverage levels for diagnostic, treatment, and care services; or on the cost, feasibility, or health and economic benefits of scaling-up effective coverage. There is an imperative for a comprehensive study to develop an investment framework to establish an evidence-based case for investing in effective interventions to address childhood cancer.
For more information, please visit: http://www.thelancet.com/campaigns/cancer/paediatric-cancer

The First Commissioner’s Meeting took place in Memphis June 17-18, pictured below.

April 2016
Grant Announcement:

Dr. Sumit Gupta is the winner of the Centre for Global Child Health Catalyst Grant for his successful proposal: ‘The Cost and Cost-Effectiveness of Treating Pediatric Hodgkin Lymphoma and Wilms Tumor in a Middle-Income Country.’

March 2016
New Publication:

Sumit Gupta, Joanne F Aitken, Ute Bartels, James Brierley, Mae Dolendo, Paola Friedrich, Soad Fuentes-Alabi, Claudia P Garrido, Gemma Gatta, Mary Gospodarowicz, Thomas Gross, Scott C Howard, Elizabeth Molyneux, Florencia Moreno, Jason D Pole, Kathy Pritchard-Jones, Oscar Ramirez, Lynn A G Ries, Carlos Rodriguez-Galindo, Hee Young Shin, Eva Steliarova-Foucher, Lillian Sung, Eddy Supriyadi, Rajaraman Swaminathan, Julie Torode, Tushar Vora, Tezer Kutluk, A Lindsay Frazier.  Paediatric cancer stage in population-based cancer registries: the Toronto consensus principles and guidelines. Lancet Oncol 2016; 17: e163–72

January 13-15, 2016
Visit to Tata Memorial Centre

Team members from the newly established Unit for Policy and Economics Research in Childhood Cancer (PERCC) made an initial visit to Tata Memorial Centre (TMC) in Mumbai, India. TMC is one of the largest cancer hospitals in the world, seeing 30,000 new patients a year, 1800 of which are under the age of 15. Drs. Horton, Gupta and Denburg met with local pediatric oncologists as well as TMC’s directors and members of the hospital administration to discuss the utility of studies focusing on determining the cost and cost-effectiveness of treating various childhood malignancies in their setting. After three days of enthusiastic meetings and sessions working out study details, PERCC and TMC have decided to collaborate on a pilot study focusing on childhood Wilms and Hodgkin lymphoma. The results will inform advocacy efforts both at TMC as well as at the international level, and will lead to studies of other pediatric cancers.

Left to right: Dr. Sumit Gupta, Sue Horton, Rajesh Dixit, Head of the IARC Mumbai Regional Hub, Dr. Brijesh Arora, Paediatric Oncologist, TMC, Dr. Tushar Vora, Paediatric Oncologist, TMC, Dr. Avi Denburg.

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January 2016

Gelband H, Sankaranarayanan R, Gauvreau CL, Horton S, Anderson BO, Bray F, Cleary J, Dare AJ, Denny L, Gospodarowicz MK, Gupta S, Howard SC, Jaffray DA, Knaul F, Levin C, Rabeneck L, Rajaraman P, Sullivan T, Trimble EL, Jha P, for the Disease Control Priorities-3 Cancer Author Group. Costs, affordability, and feasibility of an essential package of cancer control interventions in low-income and middle-income countries: Key messages from Disease Control Priorities, 3rd edition. Lancet. 2015. Published online before print.

December 1, 2015: Dr. Sumit Gupta contributes to latest Disease Control Priorities 3rd Edition volume on cancer

September is Childhood Cancer  Awareness month. 

Read the Lancet Oncology Commission article which addresses the role of primary care in the control of a global cancer epidemic.

Forum on National Childhood Cancer Strategies in Latin America (June 8-10, 2015: Geneva)

PERCC Leadership play key roles in planning and executing the Forum on National Childhood Cancer Strategies in Latin America (June 8-10, 2015) in Geneva. Links to workshop documents and testimony below.

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Dr. Gupta discusses PERCC