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Centre for Global Child Health

Matiari emPowerment and Preconception Supplementation (MaPPS) Trial

Principal Investigator: Dr. Zulfiqar A.Bhutta, Inaugural Robert Harding Chair in Global Child Health at the Hospital for Sick Children (SickKids), Toronto, Co-Director of the SickKids Centre for Global Child Health and the Founding Director of the Centre of Excellence in Women and Child Health at the Aga Khan University.

The Matiari emPowerment and Preconception Supplementation (MaPPS) Trial is a large, cluster-randomized, controlled trial evaluating the effectiveness of multiple micronutrient (MMN) supplementation provided from preconception among young women (15-24 years of age) in rural Pakistan. MMN are being provided as tablets via lady health workers, and are consistent with UNIMMAP composition. There are three study phases: preconception phase, pregnancy phase, and postpartum phase. The primary aim of this study is to evaluate the effect of MMN supplementation provided from preconception on low birth weight, compared to providing the standard of care.

Project collaborators include Aga Khan University.

Supported by: Global Affairs Canada and the Bill & Melinda Gates Foundation.

The study protocols are published in BMC's Reproductive Health:

Effect of life skills building education and micronutrient supplements provided from preconception versus the standard of care on low birth weight births among adolescent and young Pakistani women (15–24 years): a prospective, population-based cluster-randomized trial

Feasibility and effect of life skills building education and multiple micronutrient supplements versus the standard of care on anemia among non-pregnant adolescent and young Pakistani women (15–24 years): a prospective, population-based cluster-randomized trial